A tidal turbine can benefit from exquisitely designed morphing blades with a flexible trailing edge by mitigating up to 90% of the load fluctuation in harsh ocean environments, which reduces the overall cost of tidal energy. However, existing fluid–structure interaction (FSI) methods of resolving flow-induced deformation of the blades is computationally expensive, which poses an important challenge to effective morphing blade design. This paper presents a novel static FSI tool based on deep learning to cost-efficiently analyze the fluid–structure coupling of a hydrofoil. Specifically, adopting a convolutional neural network (CNN) to predict the fluid force and finite element method (FEM) to solve the solid structure response, a new CNN-FEM framework with an iterative scheme for solving the FSI problem is developed to achieve equilibrium between the fluid and structural forces. The new framework is used to predict the elastic deformation of the flexible blade section of the hydrofoil to demonstrate its effectiveness in the FSI evaluation. Comparison of the results to those produced by commercially developed software (i.e., Ansys Workbench) shows that this method yields extremely close prediction results of average equivalent stress and an accuracy of more than 92%. Moreover, it is 100 times more computationally efficient than the commercial Ansys Workbench software, requiring less than 3s for one-way FSI calculation. Taking advantage of this cost-effectiveness, the CNN-FEM can be used to achieve the accurate prediction of the deformation characteristics of the flexible hydrofoil under various flow scenarios that lay a foundation for advanced morphing blade design in the future.