Fluid-filled piping system are widely used in power cooling, fuel transportation and underwater vessel, which not only produce vibration along the system, but also transmit to the connecting structure to generate noise in ambient environment. Most investigations have concentrated on either the vibration characteristics of piping systems or of combined shells separately. In this work, an analytical impedance synthesis method (ISM) is proposed to analyze the vibration characteristics of a pipe-hull coupled system, in which the hull can be simplified to a combined conical-stiffened cylindrical-hemisphere shell. The piping system is modeled by fluid-filled beams in three-dimensional configuration. Wave function and power series solution are used to describe the displacements of cylindrical and conical shell respectively. Based on exact analytical solutions, the impedance matrix of each segment is established separately and assembled in the global coordinate by displacement continuity and force balance boundary conditions. Forced responses are compared with the experimental results to verify the correctness of the method.