In recent years, the word sustainability has been used in multiple domains ranging from finance to packaging, and the list of products and activities claiming to be sustainable grows day after day. However, a general and unambiguous definition of the term sustainability is not available and might not even be advisable because sustainability is a multifaceted concept that takes its meaning from the context of use and cannot provide a set of rules applicable everywhere (Ramsey 2015). Therefore, it remains a task for all the fields that strive to be sustainable to carve out a working definition that suits their needs. Addressing the meaning of sustainability in biodiversity informatics requires paying special attention to the data practices and infrastructures of this discipline. Over time, there has been a steep increase in the amount of biodiversity data created and shared and, at the same time, a rapid proliferation of use cases for biodiversity data. For instance, fields as different as spacial planning (Underwood et al. 2018), climate change research (Hirsch 2017), and finance (Elliot et al. 2024) rely now on biodiversity data. This growth can become unmanageable for biodiversity science, if its data practices and infrastructures do not scale up efficiently and are not sufficiently flexible to cater to the needs of a larger and more varied group of stakeholders. Biodiversity informatics has mainly addressed the financial sustainability of its infrastructures so far (Cook and Cochrane 2023; Kalfatovic et al. 2023). However, environmental and social sustainability are equally important to ensure that biodiversity science achieves its full potential. For instance, data infrastructures with lower environmental impact typically require less electricity to run continuously, and this will save money in the long run, especially at times of significant fluctuations in energy prices. Again, if biodiversity data are collected and shared while keeping in mind the necessities of multiple stakeholders, the user community will become larger and this, in turn, will offer the chance to develop fairer cost contribution agreements for running data infrastructures. More examples could be added to make the case that the three pillars of sustainability—economy, society, environment (Purvis et al. 2018)—are all equally relevant when examining data practices and infrastructures in biodiversity science. Hence, there is a need to open up a discussion on sustainability within the biodiversity community, and to promote an exchange on the topic among different stakeholders interested in biodiversity data and working with them. A community effort is required to agree upon an effective definition of sustainability in biodiversity informatics. Only such a community effort can translate this definition into practical criteria and recommendations for the sustainability of biodiversity data and infrastructures, and set milestones for their implementation. The Society for the Preservation of Natural History Collections and Biodiversity Information Standards (TDWG) are authoritative members of the biodiversity community. The aim of the talk is to involve their members in the discussion on data practices and infrastructures, addressing all the three pillars of sustainability: economy, society, and environment.