This study focuses on deriving and presenting an infinite series as the analytical solution for transient electroosmotic and pressure-driven flows in microtubes. Such a mathematical presentation of fluid dynamics under simultaneous electric field and pressure gradients leverages governing equations derived from the generalized continuity and momentum equations simplified for laminar and axisymmetric flow. Velocity profile developments, apparent slip-induced flow rates, and shear stress distributions were analyzed by varying values of the ratio of microtube radius to Debye length and the electroosmotic slip velocity. Additionally, the “retarded time” in terms of hydraulic diameter, kinematic viscosity, and slip-induced flow rate was derived. A simpler polynomial series approximation for steady electroosmotic flow is also proposed for engineering convenience. The analytical solutions obtained in this study not only enhance the fundamental understanding of the electroosmotic flow characteristics within microtubes, emphasizing the interplay between electroosmotic and pressure-driven mechanisms, but also serve as a benchmark for validating computational fluid dynamics models for electroosmotic flow simulations in more complex flow domains. Moreover, the analytical approach aids in the parametric analysis, providing deeper insights into the impact of physical parameters on electroosmotic and pressure-driven flow behavior, which is critical for optimizing device performance in practical applications. These findings also offer insightful implications for diagnostic and therapeutic strategies in healthcare, particularly enhancing the capabilities of lab-on-a-chip technologies and paving the way for future research in the development and optimization of microfluidic systems.