Although accidental fire scenes and explosions are frequently caused by more than one spark, the influencing mechanism of explosion evolution under the case of more than one spark has yet to be determined. Hence a small cuboid channel with two symmetrical sparks was deigned to investigate the effects of spark locations (IpD) and vent coefficient (Kv) on explosion flames propagation and pressures formation, which were simulated to reveal the symmetrical flame fronts and flow field interaction using a large-eddy simulation (LES). Following ignition, two symmetrical flames developed practically simultaneously until they merged to expel, at which moment, due to flow vortexes, a hollow area formed near the channel bottom beneath each configuration. The proposed correlation in this work may adequately explain the trend of experimental flame propagation velocity (v) vsKv following membrane burst. The vent pressure (Pb) and associated peak (dp/dt) remained constant while IpD changed, yet rose as Kv decreased. Surprisingly, the pressure would continue to grow after flame ejection under small IpD and Kv. The increasing trend between the maximum pressure (Pmax) and IpD was found to be met with a sigmoid function, and the Pmax also grew as the Kv climbed, a quadratic relation was discovered. This research can further understand influencing mechanism of explosion evolution in the event of more than one spark.