Flourishing Field Research Articles

Prospects of geothermal field development in Gandhar, Gujarat, India

Field development is an important part of natural resource utilization and exploration because it involves a systematic evaluation and optimization of a specific area. This study examines the geothermal field development in the Gandhar region of Gujarat, India. Gandhar for the past several decades has been a flourishing field for hydrocarbon extraction. However, as the world is dealing with environmental issues and the need to shift to cleaner and more sustainable energy sources, geothermal energy has emerged as a feasible and ecologically sound option. This study aims to understand the potential of regions in and around Gandhar as a prospective geothermal field of the west coast continental margin of India. Three primary disciplines namely geological, geochemical, and geophysical surveys are employed on the surface to assess the potential of Gandhar's geothermal resources. Geological assessments provide information about underlying geological formations, which might help to locate possible geothermal resources. The Deccan basement is a prominent source of magmatic heat, with a thermal gradient ranging from 1.29 to 1.87 W/K. This enhances Gandhar's geothermal potential by heating the underlying water in conjunction with radionuclides found in the Earth's core. The temperatures range from 60 to 80 °C according to Giggenbach triangle method. Gandhar's geothermal potential is further highlighted by the fact that its water is bicarbonate-rich, which connects it to possible subterranean aquifers. These results are verified by geophysical studies. Prospective geothermal reserves and four way closures can be found by as anomalies. Gravity survey reveal a doubly plunging antiform, with gravity high value of 5.4 and 5.3 mGa l respectively, which is corroborated by magnetic peaks of 58 and 56.2 nT Areas with higher conductivity are identified by resistivity studies, which also indicate possible fluid paths and geothermal reservoirs. The paper outlines a conceptual field development plan for the identified prospect. The basic infrastructure and the cost associated with it for field development is worked out. The cost of production/MWe of energy generation is also highlighted.

Teaching the difficult heritage of Italian Fascism

AbstractIn recent years, the architectural legacy and so-called ‘difficult heritage’ of Fascist Italy has become a flourishing field of research. These topics have also begun to make their way into the undergraduate classroom. To date, however, there has been little research carried out into the methods we use to teach the history of Fascism in particular. In this short article, we outline how we have applied problem-based learning and scenario-based learning approaches to tackle this topic. After presenting three assignments, we explain the benefits associated with a PBL/SBL approach, summarised under the headings of interdisciplinarity, creativity and authenticity, before highlighting some aspects on which colleagues may wish to reflect if they are considering adopting a similar approach in their teaching.

Structuration of Water in Microporous CAU-10-H under Gigapascal Pressure.

Employing metal-organic frameworks (MOFs) as water adsorbents has become a flourishing field in recent years. Aluminum isophthalate [Al(OH)(bdc)]·nH2O, referred to as CAU-10-H, is renowned for its high physical and chemical stability under external mechanical stimuli, which is crucial for use in sorption-based heat exchange. We report pressure-induced structural changes and water uptake/release of CAU-10-H in the gigapascal regime. CAU-10-H displays four different phases during pressurization in water up to 4.08(1) GPa. Upon immersion in water at ambient conditions, the unit cell volume expands by 1.3(1)%, by increasing water content from 78.7(1) to 85.6(1) H2O per unit cell. Upon pressurization to 1.08(1) GPa, the water content increases gradually to 112.5(1) H2O per unit cell and reduces the symmetry to P1 phase. At 1.72(1) GPa, a correlated "gate-opening/channel-closing" transition to a centrosymmetric Pnma phase occurs to increase the unit cell volume by 6.9(1)% and water content to 138.8(1) H2O per unit cell. Further increase in pressure to 4.08(1) GPa then leads to a gradual decrease in water content to 119.2(1) H2O per unit cell and redistribution of the inserted water molecules during a "gate-closing/channel-opening" transition to an I41/amd phase. After pressure removal, CAU-10-H reverts to its initial state in terms of crystallinity and water content. This pressure-induced water adsorption/desorption and concerted movements of gate-constraining ligands provides a detailed understanding of the water-MOF interplay, which can be used as a basis for designing new materials, possibly utilizing pressure as a tool for chemical modifications.

Enantioselective Synthesis of Atropisomers via Vinylidene ortho-Quinone Methides (VQMs).

Atropisomers, arising from conformational restriction, are inherently chiral due to the intersecting dissymmetric planes. Since there are numerous applications of enantiopure atropisomers in catalyst design, drug discovery, and material science, the asymmetric preparation of these highly prized molecules has become a flourishing field in synthetic chemistry. A number of catalysts, synthetic procedures, and novel concepts have been developed for the manufacture of the atropisomeric molecules. However, due to the intrinsic properties of different types of atropisomers featuring biaryl, hetero-biaryl, or non-biaryl architectures, only very few methods pass the rigorous inspection and are considered generally applicable. The development of a broadly applicable synthetic strategy for various atropisomers is a challenge. In this Account, we summarize our recent studies on the enantioselective synthesis of atropisomers using the vinylidene ortho-quinone methides (VQMs) as pluripotent intermediates.The most appealing features of VQMs are the disturbed aromaticity and axial chirality of the allene fragment. At the outset, the applications of VQMs in organic synthesis have been neglected due to their principal liabilities: ephemeral nature, extraordinary reactivity, and multireaction sites. The domestication of this transient intermediate was demonstrated by in situ catalytic asymmetric generation of VQMs, and the reactivity and selectivity were fully explored by judiciously modifying precursors and tuning catalytic systems. A variety of axially chiral heterocycles were achieved through five-, six-, seven- and nine-membered ring formation of VQM intermediates with different kinds of branched nucleophilic functional groups. The axially chiral C-N axis could be constructed from VQM intermediates via N-annulation or desymmetrization of preformed C-N scaffolds. We take advantage of the high electrophilicity of VQMs toward a series of sulfur and carbon based nucleophiles leading to atropisomeric vinyl arenes. Furthermore, chiral helical compounds were realized by cycloaddition or consecutive annulation of VQM intermediates. These achievements demonstrated that the VQMs could work as a nuclear parent for the collective synthesis of distinct and complex optically active atropisomers. Recently, we have realized the isolation and structural characterization of the elusive VQMs, which were questioned as putative intermediates for decades. The successful isolation of VQMs provided direct evidence for their existence and an unprecedented opportunity to directly investigate their reactivity. The good thermal stability and reserved reactivity of the isolated VQMs demonstrated their great potential as synthetic reagents and expanded the border of VQM chemistry.

Organocatalysis: A recent development on stereoselective synthesis of o-glycosides

ABSTRACT Organocatalysis is the use of non-stoichiometric amounts of low-molecular-weight organic molecules made up of C, H, N, O, S, and P to accelerate stereoselective chemical transformations. Despite having a long history, the use of small organic molecules as chiral catalysts in enantioselective synthesis has only recently intrigued scientists interest. However, in synthetic and medicinal chemistry, there has been a resurgence of interest in performing asymmetric synthesis of a variety of important targets by utilizing an organocatalytic approach as a leading reaction. The development of an asymmetric protocol for the synthesis of enantioenriched molecules of therapeutic relevance is crucial in the development of new drug candidates. Modern asymmetric catalysis is based on three pillars: (i) biocatalysts (i.e., enzymes), (ii) transition metal catalysis, and (iii) organocatalysis. Among these catalytic systems, organocatalysis has become the most flourishing field within the field of a catalytic regime that offers many significant benefits to synthetic and medicinal chemists. In contrast to many metal-based catalytic models, most organocatalysts have a high tolerance capability for air and moisture, easy availability, easy handling, non-toxic and enantiomeric purity, etc. They are often derived from natural resources of high enantiomeric virtue with the desired stereocentre or easily synthesized in the laboratory in some simple synthetic operations. This perspective aims to draw readers’ attention to the power of asymmetric organocatalysis in assembling glycosyl donors and acceptors in the synthesis of biologically significant stereodefined O-glycosides. Glycosylation is a fundamental chemical transformation and is ubiquitous in both nature and chemical laboratories. In nature, the glycosylation processes are carried out by enzyme catalysis. We were interested in portraying the recent impressive progress achieved by the scientific community in the field of chemical glycosylation, specifically O-glycosylation. Poly-functionalized sugar moieties offer many opportunities to discover new drug candidates in which the modification of aglycone through the glycosylation process is a key reaction.

Stewardship practice and the performance of citizenship: Greening tree-pits in the streets of Berlin

Hands-on activities of shaping and maintaining urban public green spaces, in short, “stewardship,” have become a flourishing field of civic engagement. It is the aim of this article to find out how citizenship is enacted in the everyday practice of stewardship, and how such an analysis can benefit from theories of “material participation” and “practice.” It explores this theme through a case study of the greening of tree-pits in Berlin. The article asks: (1) how people, through their doing of stewardship, engage with the tangible places that they take care of, and (2) how connections between stewardship, its focal places, and other practices shape and sustain wider public concerns. Thereby, it identifies three intersecting and materially grounded “civic nexuses of practices,” which each imply specific constructions of citizenship: civic neighboring, managed volunteering, and political mobilization. It explores how each of these nexuses emerges from the convergence of practices around the tree-pit, and probes the tensions and conflicts that they entail. In contrast to authors who have either cherished stewardship as a form of citizen empowerment, or, in line with Foucauldian governmentality studies, as the formation of governable citizen-subjects, the article emphasizes the politically ambiguous dynamics through which stewards practice their citizenship.

Between Stress and Response: Function and Localization of Mechanosensitive Ca2+ Channels in Herbaceous and Perennial Plants.

Over the past three decades, how plants sense and respond to mechanical stress has become a flourishing field of research. The pivotal role of mechanosensing in organogenesis and acclimation was demonstrated in various plants, and links are emerging between gene regulatory networks and physical forces exerted on tissues. However, how plant cells convert physical signals into chemical signals remains unclear. Numerous studies have focused on the role played by mechanosensitive (MS) calcium ion channels MCA, Piezo and OSCA. To complement these data, we combined data mining and visualization approaches to compare the tissue-specific expression of these genes, taking advantage of recent single-cell RNA-sequencing data obtained in the root apex and the stem of Arabidopsis and the Populus stem. These analyses raise questions about the relationships between the localization of MS channels and the localization of stress and responses. Such tissue-specific expression studies could help to elucidate the functions of MS channels. Finally, we stress the need for a better understanding of such mechanisms in trees, which are facing mechanical challenges of much higher magnitudes and over much longer time scales than herbaceous plants, and we mention practical applications of plant responsiveness to mechanical stress in agriculture and forestry.

Individual need and societal claims: Challenging the understanding of universalism versus selectivism in social policy

AbstractIn this article, we argue that basic social policy concepts can fertilise the discussion on active labour market policy (ALMP). During the last decades, research on ALMP has become a flourishing field. This is an overall positive development. However, the development tends to fractionate the wider picture of social policy and distance the discussion from social policy seen as a multifold set of government measures that have a direct impact on the welfare of the citizens, by providing services and/or income. We analyse a local ALMP programme in the light of three classical social policy concepts: universalism, selectivism and need. To understand what is going on in ALMP programmes, we argue that it is as important to uncover claims made by the state as it is to satisfy the human needs most often presented as the objectives of ALMP programmes. We propose that the programme under study be characterised as a hybrid, combining elements frequently perceived as dichotomies in social policy literature. Selectivism and universalism are both present as principles and the programme consists of benefits in cash and in kind.

Paths taken towards NK cell-mediated immunotherapy of human cancer-a personal reflection.

The discovery that NK cells are able to specifically recognize cells lacking the expression of self‐MHC class I molecules provided the first insight into NK cell recognition of tumour cells. It started a flourishing field of NK cell research aimed at exploring the molecular nature of NK cell receptors involved in tumour cell recognition. While much of the important early work was conducted in murine experimental model systems, studies of human NK cells rapidly followed. Over the years, human NK cell research has swiftly progressed, aided by new detailed molecular information on human NK cell development, differentiation, molecular specificity, tissue heterogeneity and functional capacity. NK cells have also been studied in many different diseases aside from cancer, including viral diseases, autoimmunity, allergy and primary immunodeficiencies. These fields of research have all, indirectly or directly, provided further insights into NK cell‐mediated recognition of target cells and paved the way for the development of NK cell‐based immunotherapies for human cancer. Excitingly, NK cell‐based immunotherapy now opens up for novel strategies aimed towards treating malignant diseases, either alone or in combination with other drugs. Reviewed here are some personal reflections of select contributions leading up to the current state‐of‐the‐art in the field, with a particular emphasis on contributions from our own laboratory. This review is part of a series of articles on immunology in Scandinavia, published in conjunction with the 50th anniversary of the Scandinavian Society for Immunology.

A Brief Review of L2MSS: Its History and Development

Motivation is a significant factor affecting L2 learning. It is not only the source power for L2 learning, but also a continuous driving force in the long and boring L2 learning process, which acts as the important emotional factor in sustaining learners’ passion for L2. So research on L2 motivation has always been a flourishing field in SLA studies for the past five decades. Since the 1970s, more and more L2 learning researchers have turned to language learners, and learning motivation has thus become the focus of their attention. This paper summarizes the four developmental stages of second language motivation theory, combs the previous studies on L2MSS at home and abroad, and introduces the background and main contents of the L2MSS theory, as well as giving a brief comment on L2MSS as the latest development in the second language motivation research.

Constitutional reasoning: A flourishing field of research in comparative law

Constitutional reasoning has been a flourishing field of research in comparative constitutional law in the past decade. This essay reviews two books that have made a significant contribution to the ...

Best practice in research - Overcoming common challenges in phytopharmacological research.

The pharmacology, toxicology and pharmacokinetics of bioactive preparations derived from natural sources has become a flourishing field of research. However, researching complex extracts and natural products faces numerous challenges. More broadly in recent years the critique of pharmacological research, and specifically its design, the methods used and reporting has intensified. This consensus document provides a perspective on what constitutes best practice in pharmacological research on bioactive preparations derived from natural sources, providing a perspective of what the leading specialist journals in the field consider as the core characteristics of good research. The editors-in-chief of seven journals developed this best practice statement in an iterative process. A first draft of the guidelines (prepared by MH) was then discussed and amended by the other editors. Core to this contribution is a table which provides detailed advice including simple points like a use of appropriate controls and the full taxonomic validity of the material under investigation (see also below), to the relevance of the model for the question being researched (e.g., can specific in silico or in vitro models really address the species anti-inflammatory activity?). Therefore, obviously, researchers must pay detailed attention to reporting and discussing such studies. This information must be discussed critically (as much as it is possible based on the published papers) in terms of their scientific quality and validity. While these points are obvious, as editors, we are aware that they are often not properly implemented. We call for an approach which incorporates a careful design, meticulous execution and a detailed reporting of studies focusing on the pharmacology/bioactivity of bioactive preparations. Clearly testable research questions must be developed and investigated experimentally. As the founder of pharmacology Claude Bernard put it already in 1865: '…. either the experimenter's hypothesis will be disproved or it will be proved by experiment. When experiment disproves its preconceived ideas, the experimenter must discard or modify it.'

Exploring A Teacher Educator’s Experiences in Modeling TPACK to Create English Language Multimedia in Technology Courses

TPACK framework as an established term for describing what teachers need to know to integrate technology effectively into their teaching practices has been widely addressed by teachers and teacher educators and it has been a flourishing field of investigation. However, teacher educators’ model in the context of using varieties of software in exploiting the benefits of technology by looking at how the framework could be implemented is restricted. Therefore the aim of this study is to explore a teacher educator’s experiences in modelling his teaching and learning based on the TPACK framework using qualitative research into biographical case study narrative. Two data collection techniques (i.e; interview and observation) were used to support the data collection process. The findings of this study suggest that it is important for teacher educators to incorporate Project Based Learning in TPACK and to combine varieties of software for creating English language multimedia as it could develop both teacher educator’s and pre-service teachers’ knowledge on content, technology, and pedagogy and their intersections. Furthermore, the use of blended learning would allow pre-service teachers to directly see, learn, observe, and experience how to learn and how to teach English using technology.

Culture and Ecology

Ecological psychology has boomed from a rare form of psychology to a flourishing field, including psychologists, sociologists, and economists. We review the development of the field from early studies to more recent advances in subsistence theories, environmental challenges, human environments, economic environments, and political environments. We also discuss frequent challenges in ecological psychology, such as reverse causality and ecological determinism, as well as ways to address these challenges. Finally, we outline paths forward including understudied regions and micro cultures.

‘Filosofie – waar is dat goed voor?’

Abstract ‘Philosophy – what is the use of it?’ Dutch philosophers about education in philosophy This article gives an overview of the ideas of twentieth-century Dutch philosophers on the use and function of education in philosophy, both in a university context and in secondary schools. In the first half of the twentieth century, there was a very strong emphasis on expanding the place of philosophy in other academic programmes, which was related to the neokantian conception of philosophy as the examination of the fundamental assumptions and the interconnectedness of the sciences. After the Second World War, this view had a unique institutional effect, in the form of the establishment of a ‘centrale interfaculteit’ at all Dutch universities, where philosophy was to be practised in relation to other disciplines. This institutional experiment was brought to an end in the 1980s. Since then, there has been a tendency to regard philosophy as an academic discipline in its own right, and less as a place for creating meaningful connections between other disciplines. From the 1970s onwards, the focus of thinking about philosophy education in the Netherlands has shifted from the universities to the secondary schools. Whereas philosophy was practically non-existent as a secondary-school subject in 1970, nowadays it has a remarkably strong presence as an elective in Dutch upper secondary education. Simultaneously, the didactics of philosophy became a flourishing field in the Netherlands, exploring the way in which secondary-school pupils can learn the skill of philosophical thinking.

TV is the Devil, the Devil is on TV: Wild Religion and Wild Media in South Africa

In keeping with trends in the academy and the rapidly increasing presence, power, and persuasion of digital and electronic media on the African continent and in the global economy, the study of religion and the media in South Africa has become a flourishing field of intellectual inquiry. The expanse of the field in terms of approaches, both methodological and theoretical, demonstrates the multiple and complex interactions between religion and the media in a diverse range of societies and settings. In light of its recent history of apartheid and transition into democracy in the middle 1990s, when paradigmatic constitutional and political changes took place in which the relationship between religion and the media was reconstituted, the South African context, in particular, is ripe for exploring media technology and practices in relation to the political economy of the sacred. This essay pays tribute to David Chidester by testing the possibilities of his theory of 'wild religion' against two vignettes of wild media in South Africa. The first, characterized as TV is the devil explores the apartheid government's pre-emptive religiously saturated ban on television. The second example, described as the devil is on TV assesses viewers' responses to the television program, Lucifer. I argue that when read with Chidester's theorization of the 'wild ambivalence of the sacred', these examples evoke the hitherto under-explored wild character of both religion and the media.

Combining different methods of data collection in public service interpreting doctoral research: examples from the Spanish context

During the past ten years, public service interpreting (PSI) has become a flourishing field of research. Different kinds of studies have explored issues such as the role of public service interpreters, accuracy and deviations in their renditions, or primary participants’ views on and expectations of PSI. In terms of research methods, it is becoming increasingly popular to combine different data collection methods in the field of PSI, especially in large research projects. The aim of this article is to describe how multiple datasets have been used in a sample of studies. It presents a review of PhD dissertations in Spain that have combined different kinds of surveys, focus groups and/or direct observation. This is followed by a description of how a multimethod approach can contribute to the advance of PSI research and how it can compensate for the limitations of certain single-method approaches to PSI. It argues that, while multimethod research may be more demanding and time-consuming from the researcher’s point of view, it is more effective in terms of providing a holistic view of the object of study.

Designing new ferroelectrics with a general strategy

The presence of a switchable spontaneous electric polarization makes ferroelectrics ideal candidates for the use in many applications such as memory and sensors devices. Since known ferroelectrics are rather limited, finding new ferroelectric materials has become a flourishing field. One promising route is to design the improper ferroelectrics. However, previous approach based on the Landau theory is not easily adopted for systems that are unrelated to the Pbnm perovskite structure. To this end, we develop a general design rule that is applicable to any system. By combining this rule with the density functional theory calculations, we identify previously unrecognized classes of ferroelectric materials. It is shown that the Rbar{3}c perovskite structure can become ferroelectric by substituting half of the B-site cations. Compound ZnSrO2 with a non-perovskite layered structure can also be ferroelectric through the anion substitution. Moreover, our approach can be used to design new multiferroics as illustrated in the case of fluorine substituted LaMnO3.

Advances in Functionalized Materials Research

In the last years, due to the rapid progress of technology, new materials at nanometric scale with special properties have become a flourishing field of research in materials science. The unique physicochemical properties of materials induced by various parameters such as mean size, shape, purity, crystallographic structure, and surface can generate effective solutions to challenging environmental and biomed-ical problems. As a result of this approach a large number of techniques were developed that enable obtaining novel materials at nanometric scale with specific and reproducible properties and parameters. Below will be highlighted studies on promising properties on the applicability of new materials that could lead to innovative applications in the medical field. Therefore, this special issue is focused on expected advances in the area of functionalized materials at nanometric scale. Due to multidisciplinarity of this topic, this special issue is comprised of a wide range of original research articles as well as review papers on the design and synthesis of functionalized nanomaterials, their structural, morphological, and biological characterization, and their potential uses in medical and environmental applications

PROVINCIALIZING AMERICA: NEW AND NOT SO NEW INTELLECTUAL HISTORIES OF WEIMAR GERMANY

Together the two volumes under review contain over forty essays on the intellectual history of Weimar Germany and its legacy today. The wide interdisciplinary field of authors, historians, philosophers, theologians, and literary, legal, and religious scholars, as well as social and political scientists, testifies to the continuing fascination of this era of thought in Anglo-American academia. With the exceptions of Mitchell G. Ash, Michael Krois, and Klaus Tanner, the authors teach at American, British or Canadian universities and represent major tendencies of the anglophone engagement with Weimar's intellectual history. Despite the fact that intellectual history of the Weimar Republic has been a flourishing field of research in Germany over the last decades, the volumes contain no contributions by German historians. This observation is by no means negligible in an age of transnational academic exchange, as may be exemplified by the recentOxford Handbook of Modern German History, which contains contributions by German, American, and British experts in their fields.