This paper describes teaching building design. The project, designed for the teaching building, prioritizes safety in its main structure, a reinforced concrete frame with six floors above ground. The story heights are 4.2m, 3.9m, 3.9m, 3.9m, 3.9m and 3.9m, respectively, and the building's total height is 27.6m. The construction site category is classified as type II, and the first group's seismic fortification intensity is 7 degrees. The process includes architectural design, structural design, and PKPM checking calculation. Architectural design mainly consists of a general description. The plan, elevation, section, and draft of the corresponding building are drawn according to the relevant information and requirements provided by the design task book. Structural design mainly includes load statistics, calculation of internal force and displacement of the frame, a combination of internal force, and calculation of staircase, slab roof, floor slab and frame structure. The calculation of displacement, internal force, and reinforcement of the whole frame structure is carried. Out using PKPM. In the course of architectural design, safety is a paramount consideration, in line with the principles of safety, applicability, beauty, economy, and energy-saving requirements, referring to national standards and relevant materials, and strictly following the requirements of relevant architectural design standards, the design of each link is not only a comprehensive scientific consideration of its own but also a related discussion with teachers, as detailed in the construction plan. The frame structure is adopted,in this structural type. It mainly includes structure layout and calculation sketch determination, load calculation, internal force calculation, internal force combination, main beam section design, and reinforcement calculation, frame column section design and reinforcement calculation, secondary beam section design and reinforcement calculation, floor and roof design, staircase design etc. Among them, the D-value method is used to calculate the internal force of the structure under horizontal load, and the distribution method is used to calculate the internal force of the structure under vertical load (dead load and live load).