Dr. Peters and colleagues continue to define pelvic pain and interstitial cystitis (IC). 1 Peters K.M. Carrico D.J. Kalinowski S.E. et al. Prevalence of pelvic floor dysfunction in patients with interstitial cystitis. Urology. 2007; 70: 16-18 Abstract Full Text Full Text PDF PubMed Scopus (101) Google Scholar The examiner identified “levator pain” using digital pressure at the ischial spines. In addition, “patients get referred pain to their low back, suprapubic area, groin, or thighs.” Reply to Letter-to-the-Editor: Prevalence of Pelvic Floor Dysfunction in Patients With Interstitial Cystitis. Urology 71: 1231, 2008UrologyVol. 71Issue 6PreviewWe appreciate the thoughtful comments regarding our paper on pelvic floor dysfunction in patients with interstitial cystitis (IC). We agree that many etiologies may be involved in the pain associated with IC and the bladder may be an “innocent bystander” in a more diffuse process. Many patients with IC suffer from other co-morbidities such as fibromyalgia, chronic fatigue syndrome, vulvodynia, and irritable bowel syndrome.1 It is doubtful that pudendal neuropathy alone would account for all of these co-morbidities. Full-Text PDF