Urban flooding occurs more frequently these days due to the increase of abnormal rainfall. A number of old city centers in South Korea have been participating in the urban regeneration project to improve their competitiveness, and low impact development (LID) practices have been used as one of the crucial measures to secure urban resilience and sustainability. By employing the LIDMOD3 simulation tool, this study examines and compares the runoff reduction effect of LID practices across different scenarios. Two existing urban regeneration project areas in Incheon were chosen as the study area, including ‘Bupyeong 11th Avenue’ in Bupyeong-gu and ‘Village of Empathy’ in Jung-gu. The results show that the annual runoff depth reduced by 39-64% and the infiltration depth increased by 252-423% in Bupyeong-gu, depending on each scenario. The runoff depth also diminished in Jung-gu by 41-69% and the infiltration depth escalated by 268-457%, varying by scenario. This study has significance by identifying the appropriate types and locations of various LID measures, in linkage with the actual regeneration projects. The findings of this study can provide a practical guideline for local governments in establishing long-term policy alternatives for flood mitigation using LID practices during the development of an urban revitalization plan.