AbstractLate Paleocene to Middle Eocene strata in the easternmost part of the Southern Pyrenees, up to 4 km thick, provide information on tectono‐sedimentary evolution of faults transversal to the Pyrenean chain. To know how changes in tectonic plate processes control the structural evolution of transverse faults and the synchronous thickness and lithological distribution of sedimentary strata in a foreland basin, field observations, interpretation of 2D seismic lines tied to lithostratigraphic data of exploration wells and gravity modelling constrains were carried out. This resulted in the following two tectono‐sedimentary phases in a foreland basin: first phase, dominated by transverse extensional faulting, synchronous with deposition of marine carbonates (ca. 57 to 51 Ma); and second phase, characterized by transverse contractional faulting, coeval to accumulation of marine and transitional siliciclastics (51 to 44 Ma). During the first phase, Iberia and Adria were moving to the east and west respectively. Therefore, lithospheric flexure in the easternmost part of the Iberian plate was developed due to that Sardinia was over‐thrusting Iberia. Consequently, activation of E‐dipping normal faults was generated giving rise to thick‐deep and thin‐shallow carbonate platform deposits across the hanging walls and footwalls of the transverse structures. During the second phase, a shearing interaction between Iberia and Sardinia prevailed re‐activating the transverse faults as contractional structures generating thin‐shelf and thick‐submarine fan deposits across the hanging walls and footwalls of the transverse structures. In the transition between the first and second phases, evaporitic conditions dominated in the basin suggesting a tectonic control on basin marine restriction. The results of our study demonstrate how thickness and lithology distribution, controlled by transverse faulting in a compressional regimen, are influenced by phases related to processes affecting motions and interactions between tectonic plates and continental blocks.