Flexible Test Platform Research Articles

Flexible Test Platform for Accelerating the Validation of Fuel Cell Powertrains

Flexible Test Platform for Accelerating the Validation of Fuel Cell Powertrains

Flexible Test Platform for Accelerating the Validation of Fuel Cell Powertrains

Flexible Test Platform for Accelerating the Validation of Fuel Cell Powertrains

An examination of the usability of the Mayo Test Drive remote cognitive testing platform in older adults with and without cognitive impairment

AbstractBackgroundMayo Test Drive (MTD): Test Development through Rapid Iteration, Validation and Expansion, is a web‐based platform for self‐administered assessment for novel (Stricker Learning Span) and open access (Symbols Test) cognitive measures with previously demonstrated validity and reliability. Our study aim was to examine the usability of MTD, defined as the extent to which MTD was used to achieve the desired study goal of completing a testing session among participants willing to engage in an all‐remote study.Methods248 Mayo Clinic Study of Aging and Mayo Alzheimer’s Disease Research Center participants were invited to participate in this ancillary, uncompensated remote pilot study via email. To examine 1) willingness to participate in a remote cognitive assessment study and 2) usability of MTD, the initiation and completion rates of MTD were examined by cognitively unimpaired (CU; n = 142) and cognitively impaired (CI; n = 106) groups (see Figure 1). These rates and other factors associated with MTD feasibility were further explored across age in CU (i.e., 50–69, 70–79, and 80+ years) and specific diagnostic groups in CI (i.e., individuals with dementia, mild cognitive impairment (MCI), and possible MCI).ResultsSession completion rate (usability) was 98% across all participants who chose to participate, and, surprisingly, completion rates did not vary by age or diagnostic groups (p = .69; see Table 1). As expected, more individuals chose to participate in the CU (77%) versus CI (52%) group (p < .001). In terms of feasibility, individuals over 80 and with CI were more likely to have some contact with the study coordinator. Use of smartphones decreased with age, with most CU individuals over 70 using a personal computer (69‐73%; Table 2).ConclusionsThough the CI group was less likely to choose to participate than the CU group, out of those that did choose to participate the rate of completion was 98%. This demonstrates high usability of MTD. Study coordinator support and a flexible testing platform is critical for facilitating participation in remote testing across the aging population, and more supports and incentives may be needed for individuals with cognitive impairment to improve participation rates.

An examination of the usability of the Mayo Test Drive remote cognitive testing platform in older adults with and without cognitive impairment.

Mayo Test Drive (MTD): Test Development through Rapid Iteration, Validation and Expansion, is a web-based platform for self-administered assessment for novel (Stricker Learning Span) and open access (Symbols Test) cognitive measures with previously demonstrated validity and reliability. Our study aim was to examine the usability of MTD, defined as the extent to which MTD was used to achieve the desired study goal of completing a testing session among participants willing to engage in an all-remote study. 248 Mayo Clinic Study of Aging and Mayo Alzheimer's Disease Research Center participants were invited to participate in this ancillary, uncompensated remote pilot study via email. To examine 1) willingness to participate in a remote cognitive assessment study and 2) usability of MTD, the initiation and completion rates of MTD were examined by cognitively unimpaired (CU; n = 142) and cognitively impaired (CI; n = 106) groups (see Figure 1). These rates and other factors associated with MTD feasibility were further explored across age in CU (i.e., 50-69, 70-79, and 80+ years) and specific diagnostic groups in CI (i.e., individuals with dementia, mild cognitive impairment (MCI), and possible MCI). Session completion rate (usability) was 98% across all participants who chose to participate, and, surprisingly, completion rates did not vary by age or diagnostic groups (p =.69; see Table 1). As expected, more individuals chose to participate in the CU (77%) versus CI (52%) group (p < .001). In terms of feasibility, individuals over 80 and with CI were more likely to have some contact with the study coordinator. Use of smartphones decreased with age, with most CU individuals over 70 using a personal computer (69-73%; Table 2). Though the CI group was less likely to choose to participate than the CU group, out of those that did choose to participate the rate of completion was 98%. This demonstrates high usability of MTD. Study coordinator support and a flexible testing platform is critical for facilitating participation in remote testing across the aging population, and more supports and incentives may be needed for individuals with cognitive impairment to improve participation rates.

An Integrated Testing Solution for Piezoelectric Sensors and Energy Harvesting Devices

Abstract With the fast growth of wireless communications between nodes and sensor units and the increase of devices installed in remote places, and the development of IIoT applications, new requirements for power energy supply are needed to assure device functionality and data communication capabilities during extended periods of time. For these applications, energy harvesting takes place as a good solution to increase the autonomy of remote measuring solutions, since the usage of conventional power supply solutions has clear limitations in terms of equipment access and increased maintenance costs. In this context, regenerative energy sources such as thermoelectric, magnetic and piezoelectric based, as well as renewable energy sources, such as photovoltaic and wind based, among others, make the development of different powering solutions for remote sensing units possible. The main purpose of this paper is to present a flexible testing platform to characterize piezoelectric devices and to evaluate their performance in terms of harvesting energy. The power harvesting solutions are focused on converting the energy from mechanical vibrations, provided by different types of equipment and mechanical structures, to electrical energy. This study is carried out taking into account the power supply capabilities of piezoelectric devices as a function of the amplitude, frequency and spectral contents of the vibration stimulus. Several experimental results using, as an example, a specific piezoelectric module, are included in the paper.

A Comprehensive Study and Validation of a Power-HIL Testbed for Evaluating Grid-Connected EV Chargers

Integration of excessive electric vehicle (EV) chargers into the low-voltage (LV) network may introduce new challenges. Power hardware in the loop (PHIL) simulations can be used for evaluating such systems as it provides a flexible testing platform to study the overall system as well as individual devices. To facilitate a proper PHIL simulation, a precise mathematical model of the PHIL testbed is required. This article presents a comprehensive small-signal model capable of describing the dynamics of a PHIL testbed developed for evaluating grid-connected EV chargers. The PHIL testbed consists of a PHIL-based battery emulator (BE) and a grid emulator (GE) to mimic the dc side battery energy storage system (BESS) and the ac side LV grid behavior, respectively. A mathematical framework is developed to analyze the stability and predict the accuracy of both PHIL-based emulators. The BE in this article considers a switch-mode power amplifier (PA). Thus, design strategies for its linear controller are also discussed in the context of cascaded dc–dc configuration. An experimental PHIL platform based on a real-time simulator (RTS) has been used to validate theoretical predictions and confirm developed models. Finally, the validated PHIL test has been employed for analyzing the performance of a commercial EV charger and its interactions with a weak LV network simulated in RSCAD/EMTDC.

A Functionalized Paper Strip‐Based Platform for Rapid Detection of Anticancer Drug Concentrations

This article presents a compact, low‐cost, robust, and flexible test platform for determining the concentration of drugs in fluids. This device is based on a PVC foil card containing copper conductive foils in which disposable paper test strips are inserted. The paper test strips are overlaid with deposition of multiwalled carbon nanotubes (MWCNTs) acting as a sensing layer. When a paper test strip is inserted into the test card, the conductive path between two copper lines is established. A drop of test fluid on the sensing MWCNT layer changes the conductivity in a concentration‐dependent manner, enabling calculation of the drug concentration after measurement of the electrical resistance at the copper terminals. An equivalent electrical circuit was also proposed to model the response of the fabricated sensor. It was shown that model parameters are dependent on the concentration of the cytostatic drug methotrexate. Additionally, the fabricated sensor demonstrated the ability to differentiate the same concentration of methotrexate and cyclophosphamide. The complete readout electronics and polynomial transfer function for calculating drug concentrations were also developed and are presented.

Validation of a Test Platform to Qualify Miniaturized Electric Propulsion Systems

Miniaturized electric propulsion systems are one of the main technologies that could increase interest in CubeSats for future space missions. However, the integration of miniaturized propulsion systems in modern CubeSat platforms presents some issues due to the mutual interactions in terms of power consumption, chemical contamination and generated thermal and electro-magnetic environments. The present paper deals with the validation of a flexible test platform to assess the interaction of propulsion systems with CubeSat-technologies from mechanical, electrical, magnetic, and chemical perspectives. The test platform is a 6U CubeSat hosting an electric propulsion system and able to manage a variety of electric propulsion systems. The platform can regulate and distribute electric power (up to 60 W), exchange data according to several protocols (e.g., CAN bus, UART, I2C, SPI), and provide different mechanical layouts in 4U box completely dedicated to the propulsion system. Moreover, the data gathered by the onboard sensors are combined with the data from external devices and tools providing unprecedented information about the mutual behavior of a CubeSat platform and an electric propulsion system.

Implementation and Quality Control of Lung Cancer EGFR Genetic Testing by MALDI-TOF Mass Spectrometry in Taiwan Clinical Practice.

Molecular diagnostics in cancer pharmacogenomics is indispensable for making targeted therapy decisions especially in lung cancer. For routine clinical practice, the flexible testing platform and implemented quality system are important for failure rate and turnaround time (TAT) reduction. We established and validated the multiplex EGFR testing by MALDI-TOF MS according to ISO15189 regulation and CLIA recommendation in Taiwan. Totally 8,147 cases from Aug-2011 to Jul-2015 were assayed and statistical characteristics were reported. The intra-run precision of EGFR mutation frequency was CV 2.15% (L858R) and 2.77% (T790M); the inter-run precision was CV 3.50% (L858R) and 2.84% (T790M). Accuracy tests by consensus reference biomaterials showed 100% consistence with datasheet (public database). Both analytical sensitivity and specificity were 100% while taking Sanger sequencing as the gold-standard method for comparison. EGFR mutation frequency of peripheral blood mononuclear cell for reference range determination was 0.002 ± 0.016% (95% CI: 0.000–0.036) (L858R) and 0.292 ± 0.289% (95% CI: 0.000–0.871) (T790M). The average TAT was 4.5 working days and the failure rate was less than 0.1%. In conclusion, this study provides a comprehensive report of lung cancer EGFR mutation detection from platform establishment, method validation to clinical routine practice. It may be a reference model for molecular diagnostics in cancer pharmacogenomics.

Flexible testing platform for employment of RFID-enabled multi-agent system on flexible assembly line

The success of a flexible assembly line (FAL) depends on efficacious scheduling and control architecture. However, the scheduling and control architectures currently employed in FALs lack the flexibility and reconfiguration capacity to manage disturbances when they occur. Consequently, the system performance rapidly degrades when the system operation is interrupted. The objective of this study is to examine the potential enhancement of FAL performance through the use of a radio-frequency-identification-enabled multi-agent scheduling and control system (RFID-enabled MASCS). A simulation test platform is developed for the examination of an RFID-enabled MASCS in a FAL, and several system performance measures are considered in the simulation test platform. The results indicate that the RFID-enabled MASCS can increase the uptime productivity and production rate of a FAL. A real case-study test is performed, and a 22% decrease in lead time along with significant improvements in other system performance indicators are observed, especially when a series of disturbances occur within the examined assembly machine.

A highly sensitive and flexible magnetic nanoprobe labeled immunochromatographic assay platform for pathogen Vibrio parahaemolyticus

A magnetic nanoprobe labeled immunochromatographic test strip (MNP/ICTS) was developed to detect food-borne pathogen Vibrio parahaemolyticus. Specific antibody against V. parahaemolyticus was used as test line by coating onto the nitrocellulose membrane. Magnetic nanoprobe was prepared by immobilizing the specific antibody onto the surface of superparamagnetic nanoparticles. Specificity and sensitivity of the MNP/ICTS system were verified by artificially contaminated shrimp homogenate samples. Reliability and application feasibility of the MNP/ICTS system were demonstrated by using seafood samples (n=36). Comparing with polymerase chain reaction (PCR) and traditional culture methods, the MNP/ICTS system is found to be not only a rapid qualitative analysis (~10min), but also an accurately quantitative detection platform. Through its rapid magnetic separation property, the MNP/ICTS system is capable to flexibly combine with a sample enrichment and pre-incubation process. This combination makes the qualitative sensitivity for the food samples surged more than 100-fold. A naked-eye observation of 1.58×102CFU/g V. parahaemolyticus was realized. This sensitivity could meet the V. parahaemolyticus test threshold value in many countries. Also, the total sample pre-treatment plus MNP/ICTS assay only needs about 4.5h. Namely, we can get test results in a day. Hence, the developed MNP/ICTS assay platform is simple, rapid and highly sensitive. It is a flexible test platform for pathogen detection. The favorable comparison with PCR and culture methods further proves that the developed MNP/ICTS is applicable into food-borne pathogen or other areas where a simple, rapid, sensitive and point-of-care analysis is desirable.

Ozone Sensor on Flexible Substrate by ZnO Nanoparticles

In this work the ozone detection in flexible substrate has been investigated. The flexible test platform with an integrated heater was designed and then characterized by thermal simulations using finite elements and its electrical properties have been studied. ZnO nanoparticles were deposited by drop coating process on the flexible substrate with platinum interdigited electrodes for gas detection. The gas sensing properties were determined by ozone exposure at different concentrations and temperatures. The gas sensing measurements present good response at different gas concentrations, good repeatability and fast recovery.