This comprehensive review explores the forefront of nanohybrid materials, focusing on the integration of coordination materials in various applications, with a spotlight on their role in the development of flexible solar cells. coordination material-based nanohybrids, characterized by their unique properties and multifunctionality, have garnered significant attention in fields ranging from catalysis and sensing to drug delivery and energy storage. the discussion investigates the synthesis methods, properties, and potential applications of these nanohybrids, underscoring their versatility in materials science. Additionally, the review investigates the integration of coordination nanohybrids in perovskite solar cells (PSCs), showcasing their ability to enhance the performance and stability of next-generation photovoltaic devices. the narrative further expands to encompass the synthesis of luminescent nanohybrids for bioimaging purposes and the development of layered two-dimensional (2D) material-based nanostructured hybrids for energy storage and conversion. the exploration culminates in an examination of the synthesis of conductive polymer nanostructures, elucidating their potential in drug delivery systems. lastly, the article discusses the cutting-edge realm of flexible solar cells, emphasizing their adaptability and lightweight design. Through a systematic examination of these diverse nanohybrid materials, this review sheds light on the current state of the art, challenges, and prospects, providing valuable insights for researchers and practitioners in the fields of materials science, nanotechnology, and renewable energy.