The BRST structure of the extended Bondi-Metzner-Sachs symmetry group of asymptotically flat manifolds is investigated using the recently introduced framework of the Beltrami field parametrization of four-dimensional metrics. The latter identifies geometrically the two physical degrees of freedom of the graviton as fundamental fields. The graded BRST BMS4 nilpotent differential operator relies on four horizontality conditions giving a Lagrangian reformulation of the asymptotic BMS4 symmetry. A series of cocycles is found which indicate the possibility of anomalies for three-dimensional Lagrangian theories to be built in the null boundaries of asymptotically flat spaces from the principle of BRST BMS4 invariance.