Flash floods are catastrophic phenomena that pose a serious risk to coastal infrastructures, towns, villages, and cities. This study assesses the risk of flash floods in the ungauged Mekkah province region based on specific and effective morphometric and topographic features characterizing the study region. Shuttle Radar Topography Mission (SRTM) data were employed to construct a digital elevation model (DEM) for a detailed analysis, and the geographical information systems software 10.4 (GIS) was utilized to assess the linear, area, and relief aspects of the morphometric parameters. The ArcHydro tool was used to prepare the primary parameters, including the watershed border, flow accumulation, flow direction, flow length, and stream ordering. The study region’s flash flood hazard degrees were assessed using several morphometric characteristics that were measured, computed, and connected. Two different and effective methods were used to independently develop two models of flood vulnerability behaviors. The integrated method analysis revealed that most of the eastern and western parts of the studied province provide high levels of flood vulnerability. Due to it being one of the most helpful topographic indices, the integrated flood vulnerability final map was overlayed with the topographic position index (TPI). The integrated results aided in understanding the link between the general basins’ morphometric characteristics and their topographical features for mapping the different flood susceptibility locations over the entire studied province. Thus, this can be applied to investigate a surface-specific reduction plan against the impacts of flood hazards in the studied landscape.