Fixed Orthodontic Appliances Research Articles

Sectional Fixed Orthodontic Appliance for Management of a Pseudo Class III Malocclusion. Case Report

Background: Proper diagnosis and treatment planning are the first steps in the management of pseudo-Class III malocclusion.
 Case Presentation: An 11 years old male patient with pseudo- class III malocclusion.
 Conclusion: A class I molar with average overjet and overbite was achieved with a sectional fixed orthodontic appliance.
 Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 262-265

Treatment Satisfaction and Quality of Life Changes in Patients Receiving Conventional Fixed Orthodontic Appliances and Clear Aligner Therapy: A Questionnaire Based Cross-sectional Study

Introduction: The orthodontic outcome is mainly decided by the objective evaluation by orthodontists with minimal subjective considerations. Although there is increasing patient acceptance of orthodontic aligners for malocclusion treatment, minimal evidence exists regarding their efficacy and adverse effects compared to conventional fixed orthodontic appliances. Aim: To assess patient satisfaction and quality of life changes after these two modalities of orthodontic treatment and to analyse the influencing co-factors. Materials and Methods: A web-based three-part questionnaire survey was done amongst 303 participants who underwent either fixed orthodontic therapy or invisalign treatment. The first part collected the participants’ demographic details and their treatment type. The second part of five questions addressed their preferences, facilitators, and factors preventing them from undergoing orthodontic treatment. The final part of ten questions measured the satisfaction ratio on a five-point Likert scale. Descriptive statistics were computed to provide an overview of responses using frequencies and percentages. Inferential statistics were computed using the chi-square test, and a p-value less than 0.05 was considered statistically significant. Results: This study of 303 orthodontic patients found no significant difference in overall satisfaction between fixed braces and clear aligners (p=0.989), although aligners were favoured for facial appearance, increased treatment costs were a concern for the majority. Female participants (185, 61.1%) constituted the majority of the participants, with 178 (58.7%) aged between 19- 29 years. Clear aligner users experienced more discomfort with additional visits and appointment booking, while fixed braces users had greater concerns about appearance and increased brushing time. Younger patients reported higher satisfaction across several treatment aspects (p=0.013). Men were more satisfied with treatment duration and costs than women. Conclusion: In conclusion, while clear aligners provide aesthetic and hygiene benefits, overall satisfaction was comparable to fixed braces, with cost being a significant factor. Comprehensive consultations are essential to align treatment with patient needs. Future research should involve larger, more diverse samples for validation.

Effects of Fixed Orthodontic Appliance with Antihypertensive Drugs on the Body Weight of Experimental Rats

Background: This study aims to investigate the effect of fixed orthodontic appliances and/or antihypertensive drugs on the weight of experimental rats. Materials and Methods: Thir-ty-six male Wistar albino rats were subjected to a split-mouth design study, in which an orthodontic appliance was inserted in one side to move the first molar mesially for 2 weeks while the other side acted as a control to tooth movement. The rats were allocated into three groups: group A (n = 12), without any pharmacological treatment; group B (n = 12), subcu-taneous injection of bisoprolol fumarate (5 mg/kg) daily; and group C (n = 12), subcutaneous injection of valsartan (10 mg/kg) daily. A fixed orthodontic appliance with a closing coil spring delivering 50 gm of force was used to move the first molar mesially while the incisors served as an anchor unit. The weight of the rats was measured on days 1 (the day of appli-ance insertion), 7, and 14. Results: No significant (P > 0.05) difference in the body weight of rats was found among the three groups at each time point; however, significant (P < 0.05) weight loss was noted after the first and second week of the experiment in all study groups. Conclusion: The body weight loss of rats following the insertion of a fixed orthodontic ap-pliance could be related to the effects of the appliance rather than the administered antihy-pertensive drugs.

Knowledge, Attitude, and Practice of Oral Healthcare Among Patients With Fixed Orthodontic Appliance: A Cross-sectional Survey in Yazd City, Iran

Knowledge, Attitude, and Practice of Oral Healthcare Among Patients With Fixed Orthodontic Appliance: A Cross-sectional Survey in Yazd City, Iran

Corrosion of Fixed Orthodontic Appliances: Causes, Concerns, and Mitigation Strategies

The orthodontic supply market is a prosperous billion-dollar industry, driven by an increasing demand for orthodontic appliances. The supremacy of metallic first-generation biomaterials is evident for manufacturing brackets, archwires, bands, and other components due to their well-recognized chemical inertness, spontaneous passivation, biocompatibility, and favorable mechanical properties combination. However, the oral cavity is the ultimate corrosion-promoting environment for any metallic material. In this work, the general picture of the intraoral degradation of fixed orthodontic appliances is first addressed, from the causes to the harmful effects and their oral clinical implications. Current mitigation strategies are also pointed out, including the alloys’ bulk composition adjustment combined with new and advanced manufacturing processes and/or their surface treatment or coating deposition. The versatile use of thin films and coatings stands out with different deposition technologies: Many in vivo and in vitro efforts have been devoted to oral aging, from monolithic to composite architectures and micro- to nano-scale materials, to meet the best and safest oral practice demands. Unfortunately, literature data suggest that even the existing commercially available protective coatings have drawbacks and are fallible. Further multidisciplinary research is still required to effectively mitigate the corrosion behavior of fixed orthodontic appliances.

Comparative Evaluation of Postoperative Facial Swelling and Occlusion in Orthognathic Treatment with Clear Aligners versus Fixed Orthodontic Appliances: A Systematic Review

The purpose of this systematic review was to assess the postoperative facial swelling (FS) and occlusion attained with clear aligner therapy (CAT) and fixed orthodontic therapy (OT) after orthognathic surgery (OS). The focused question was “Is there a difference in postoperative FS and occlusion attained with CAT and fixed OT after OS?” Indexed databases were searched up to and including October 2023 using different keywords. Original clinical studies that compared postoperative FS and occlusion attained with CAT and fixed OT after OS were included. Risk of bias (RoB) and quality of evidence were also assessed. Four retrospective studies were included. One study reported no difference in postoperative FS among patients that underwent CAT or fixed OT after OS. In one study, patients treated with CAT demonstrated less FS in the first post-surgical week than individuals that underwent fixed OT. In one study, postoperative occlusion was comparable among patients that underwent CAT or fixed OT, whereas in another, postoperative occlusion was better in patients that underwent fixed OT than CAT. All studies had a moderate RoB and none of the investigations were based on power-adjusted data. Based upon the sparsity and questionable quality of available evidence, there is a need to render a firm conclusion. However, it seems that CAT and fixed OT are comparable in relation to postoperative occlusion and FS after OS.

Changes in the pH and the Flow Rate of Saliva During Orthodontic Treatment with Fixed Orthodontic Appliances: A Systematic Review.

This systematic review aimed to assess salivary flow and pH changes at various stages of orthodontic treatment with fixed appliances. A comprehensive searches in electronic databases, including Medline, ResearchGate, Web of Science, SAGE Journals, Cochrane Oral Health Group's Trials Register, and ScienceDirect, without any publication date restrictions until January 2022 was conducted. The Pre-ferred Reporting Items for Reporting Systematic Reviews and Meta Analyses (PRISMA 2020 version) protocol was adopted and the risk of bias assessments were performed using the Cochrane ROBINS-I tool for non-randomized studies. Out of 4902 articles, 25 were fully evaluated, and seven studies that met the inclusion criteria were included in the review. The results showed that orthodontic treatment with fixed orthodontic appliances increased the stimulated salivary flow rate during various stages of treatment. However, the unstimulated salivary flow rate showed different changes. Furthermore, stimulated salivary pH increased, whereas unstimulated salivary pH significantly decreased, depending on the specific period of orthodontic treatment. Overall, fixed orthodontic appliances have an impact on salivary flow rate and pH during different stages of treatment. Nevertheless, the current literature is insufficient to draw definitive conclusions. More well-designedrandomized studies with larger sample sizes are necessary to confirm these findings.

Inflammatory parameters and color alterations of dental bleaching in patients wearing fixed orthodontic appliance: a randomized clinical trial

BackgroundMany orthodontic patients request dental bleaching during orthodontic treatment to achieve a faster aesthetic resolution, however, no attention has been paid to the inflammatory processes that can occur when both therapies are indicated together. So, this clinical trial evaluated the inflammatory parameters and color alterations associated with dental bleaching in patients wearing a fixed orthodontic appliance.MethodsThirty individuals aged between 18 and 40 years were equally and randomly allocated into three groups: FOA (fixed orthodontic appliance), BLE (dental bleaching), and FOA + BLE (fixed orthodontic appliance + dental bleaching). The orthodontic appliances and the bleaching procedures were performed in the maxillary premolars and molars. For dental bleaching a 35% hydrogen peroxide was used. The gingival crevicular fluid (GCF) and nitric oxide (NO-) levels were evaluated at different time-points. Color evaluation was performed using an Easyshade spectrophotometer at baseline (FOA, FOA + BLE, BLE), one month after (FOA + BLE) and 21 days after appliance removing (FOA + BLE and FOA groups), in each tooth bleached. The ANOVA and Tukey’s tests, with a significance level of 5%, were used for statistical analysis.ResultsThe GCF volume in the FOA + BLE and FOA groups significantly increased at the time points evaluated (p < 0.001); however, this did not occur in the BLE group (p > 0.05). On the other hand, NO- levels significantly decreased during dental bleaching with or without fixed orthodontic appliances (FOA + BLE and BLE groups; p < 0.05), while no significant changes were observed in the FOA group (p > 0.05). Significant changes in color were observed in the FOA + BLE and BLE groups compared to in the FOA group (p < 0.01). However, the presence of fixed orthodontic appliance (FOA + BLE) negatively affected the bleaching efficacy compared to BLE group (p < 0.01).ConclusionsDental bleaching did not increase the inflammatory parameters in patients wearing fixed orthodontic appliance. However, in the presence of orthodontic appliances, the bleaching efficacy was lower than that of bleaching teeth without orthodontic appliances.Trial registrationRBR-3sqsh8 (first trial registration: 09/07/2018).

Studying the Corrosion Effect of Fixed Orthodontic Appliances on Thyroid Hormones

This study aimed to determine the nickel (Ni), and chromium (Cr) ions amounts and investigate their potential effects on thyroid hormones in patients' saliva who were receiving treatment with fixed orthodontic appliances (FOA). In this study, 42 FOA volunteers participated, and all samples were obtained from a specialized center for manufacturing and orthodontics in Bab Al-Moadham, Baghdad, Iraq. According to the findings, individuals with fixed orthodontics have significantly higher levels of the thyroid hormones (P&lt;0.05) FT3 and FT4 than those who did not have orthodontic treatment, whereas there were no significant changes in TSH (P=0.599). Additionally, the amounts of Ni+2 and Cr+3 were considerably higher in the individuals receiving metallic orthodontic treatment (P &lt;0.0001). The findings of this investigation support the hypothesis that corrosion metals from the FOA have a meaningful impact on the concentration of Ni and Cr ions and, consequently, on the thyroid and salivary functioning of the patient group.

Effect of Mobile Phone with and without Earphones Usage on Nickel Ion Release from Fixed Orthodontic Appliance.

This study is an attempt to assess whether the usage of headphones could minimize the nickel ion release from fixed orthodontic appliance compared with hand-held mobile phones. The aim of the study is to validate the hypothesis whether there is a significant variation in nickel ion release from fixed orthodontic appliance among the patients using hand-held mobile phones and patients using mobile earphones. This is a cross-sectional study where a total of 60 healthy individuals who were undergoing fixed orthodontic treatment in the Department of Orthodontics and Dentofacial Orthopedics, Adhiparasakthi Dental College and Hospital, Melmaruvathur, Chennai, India, and all these individuals were bonded and banded. All of them are class I malocclusion with bimaxillary protrusion. Salivary samples were collected in their regular checkup after two months and 7th, 14th, and 21st days salivary nickel level was evaluated based on their usage of mobile phones with earphones and without earphones. In this study, paired and independent t-tests were used. On basis of statistics results, the mean of nickel release in both male and female participants using mobile phones without earphones were significantly higher than the participants using mobile phone with earphones. By our study, we concluded that usage of mobile phones with earphones has a significant reduced effect on metal ion release from fixed orthodontic appliance when compared to usage of mobile phones without earphones.

Traumatic Ulcers in a Patient Using Fixed Orthodontic Appliances with Moderate Oral Hygiene

Traumatic Ulcers in a Patient Using Fixed Orthodontic Appliances with Moderate Oral Hygiene

Toxicity of Metal Ions Released from a Fixed Orthodontic Appliance to Gastrointestinal Tract Cell Lines.

The mechanism of toxicity and cellular response to metal ions present in the environment is still a very current area of research. In this work, which is a continuation of the study of the toxicity of metal ions released by fixed orthodontic appliances, eluates of archwires, brackets, ligatures, and bands are used to test the prooxidant effect, cytotoxicity, and genotoxicity on cell lines of the gastrointestinal tract. Eluates obtained after three immersion periods (3, 7, and 14 days) and with known amounts and types of metal ions were used. Four cell lines-CAL 27 (human tongue), Hep-G2 (liver), AGS (stomach) and CaCo-2 (colon)-were treated with each type of eluate at four concentrations (0.1×, 0.5×, 1.0×, and 2.0×) for 24 h. Most eluates had toxic effects on CAL 27 cells over the entire concentration range regardless of exposure time, while CaCo-2 proved to be the most resistant. In AGS and Hep-G2 cells, all samples tested induced free radical formation, with the highest concentration (2×) causing a decrease in free radicals formed compared to the lowest concentrations. Eluates containing Cr, Mn, and Al showed a slight pro-oxidant effect on DNA (on plasmid φX-174 RF I) and slight genotoxicity (comet assay), but these effects are not so great that the human body could not "resist" them. Statistical analysis of data on chemical composition, cytotoxicity, ROS, genotoxicity, and prooxidative DNA damage shows the influence of metal ions present in some eluates on the toxicity obtained. Fe and Ni are responsible for the production of ROS, while Mn and Cr have a great influence on hydroxyl radicals, which cause single-strand breaks in supercoiled plasmid DNA in addition to the production of ROS. On the other hand, Fe, Cr, Mn, and Al are responsible for the cytotoxic effect of the studied eluates. The obtained results confirm that this type of research is useful and brings us closer to more accurate in vivo conditions.

PATIENT'S DISCOMFORT ASSOCIATED WITH FIXED ORTHODONTIC APPLIANCES TREATMENT

To determine the prevalence and factors causing discomfort during fixed orthodontic treatment. Two hundred patients of fixed orthodontic patients in UiTM clinics who were willing to participate and could consent to the research were selected. The participants were randomly selected for this research in the odd number sequence from the population size of 740 individuals. Data was collected employing an Oral Impact on Daily Performance questionnaire to assess discomfort intensity and bio-psychosocial variables. Statistical analysis used was descriptive statistics and chi-squared statistics. The prevalence of discomfort in patients with fixed orthodontic appliances was 92% (mean: 0.92, standard deviation: 0.27), which covers 184 of the samples. Eating food (68%), speaking clearly (37%), cleaning teeth (64%), sleeping (21%), smiling and laughing, and showing teeth without embarrassment (21%) remained independently associated with a greater prevalence of discomfort (P ≤ 0.05). The patient wearing fixed orthodontics appliances has a high prevalence of discomfort. The factors associated with the discomfort included eating food, speaking, cleaning teeth, sleeping, and smiling and laughing, showing teeth without embarrassment.

Treatment Effectiveness of Clear Aligners in Correcting Complicated and Severe Malocclusion Cases Compared to Fixed Orthodontic Appliances: A Systematic Review.

This systematic review aimed to critically assess the available evidence regarding the effectiveness and efficiency of clear aligners in the comprehensive treatment of complex cases accompanied by premolars extraction. An electronic literature search by two reviewers was independently done on 27 February 2023 in the following databases without time and language limitations: Pubmed®, Scoups®, Google Scholar, Cochrane Library database, Web of Science™, and Proquest Database Open. Randomized controlled trials (RCTs) of any type, non-randomized clinical trials (CCT), cohort studies, and prospective, retrospective, and cross-sectional studies were reviewed. The risk of bias in included studies was assessed using the Risk of Bias (RoB 2.0) tool for randomized trials and the Risk of Bias in Non-randomized Studies (ROBINS-I) tool for non-randomized studies. After carefully searching the literature, six trials were included in this systematic review, three RCTs, two retrospective cohort studies, and one CCT. Two hundred eighty-three patients were included (186 females, 97 males). Three studies found that there were no differences between the clear aligners and fixed appliances when evaluations were done using the American Board of Orthodontists Objective Grading System (ABO-OGS) or the Peer Assessment Rating (PAR) index. Two studies found that there were some differences between predicted and achieved tooth movements when clear aligners were used in premolars extraction cases. Based on the included studies, the duration of treatment was shorter with fixed appliances than the clear aligners when applied to orthodontic extraction cases. Both clear aligners and fixed appliances were found effective in the orthodontic treatment of premolar extraction-based cases. Fixed appliances have the advantage of achieving better buccolingual inclination and occlusal contacts in a shorter treatment duration. Treatment with clear aligners might be associated with differences between predicted and achieved tooth movements. Therefore, the characteristics of these techniques should be considered when making a treatment decision.

The Changes in Nickel and Chromium Ion Levels in Saliva with Fixed Orthodontic Appliances: A Systematic Review

Fixed orthodontic appliances (braces systems) contain variable amounts of nickel and chromium, which can lead to immune responses and allergic reactions. The objective of the present review was to evaluate the changes in the quantity of nickel and chromium in saliva among patients wearing braces systems. The electronic databases used to perform the search were Pubmed, ReasearchGate, and Google scholar. After an initial search of these electronic databases, 12 studies were included in the systematic literature review. Overall, 554 patients wearing non-removable orthodontic appliances participated in the research that we reviewed. The age of the subjects ranged from 11 to 35 years. The quantity of chromium and nickel ions in saliva was measured before the braces systems were placed and after some period of having them. After evaluating the changes in nickel and chromium levels in saliva during orthodontic treatment with fixed brackets, it can be concluded that there is an increase in the levels of nickel and chromium ions in saliva. There is a significant increase in these ions after placement of the orthodontic appliances, peaking from three to six months, but not reaching toxic levels. The levels then gradually decrease. A full and detailed examination of the patient before starting orthodontic treatment is important, and alternative orthodontic appliances for patients who are allergic to nickel and/or chromium should be recommended.

MALDI-TOF/MS Profiling of Whole Saliva and Gingival Crevicular Fluid in Patients with the Invisalign System and Fixed Orthodontic Appliances.

The movement of teeth by orthodontic treatment with the Invisalign (IN) system and fixed orthodontic appliances (FOA) is characterized by the reconstruction of periodontal ligaments, alveolar bone, and gingiva. A reflection of these phenomena can be found in the composition of gingival crevicular fluid (GCF). A total of 90 samples from 45 participants (45 whole saliva and 45 GCF), including 15 patients with FOA, 15 patients with IN, and 15 patients with oral health, were subjected to matrix-assisted laser desorption/ionization mass spectrometry (MALDI-TOF/MS) analysis. Mass fingerprints were generated for each sample. Three models were tested: a quick classifier (QC), a genetic algorithm (GA), and a supervised neural network (SNN). For both groups of samples (saliva and GCF), the GA model showed the highest recognition abilities of 88.89% (saliva) and 95.56% (GCF). Differences between the treated (FOA and IN) groups and the control group in saliva and GCF samples were determined using cluster analysis. In addition, we monitored the effect of long-term orthodontic treatment (after 6 months) in the lag phase of orthodontic tooth movement. The results show increased levels of inflammatory markers (α-defensins), which may indicate an ongoing inflammatory process even after 21 days from force application.

Curcumin Gel Versus Chlorhexidine Gel for Treatment of Chronic Gingivitis Associated with Fixed Orthodontic Appliance

Background and aims: Gingivitis in orthodontic treatment remains a challenging and undesirable consequence of orthodontic treatment. Hence, a variety of chemical or herbal agents, methods, and techniques have been investigated to prevent or reduce gingivitis that occurs in orthodontic treatment. In this study, we will evaluate and compare the effect of curcumin (CMN) gel with chlorhexidine (CHX) gel on clinical parameters (plaque and gingival index) and oral bacterial number (total bacterial count test) in fixed orthodontic patients that have gingivitis. We are the first to use curcumin gel for patients that have gingivitis with fixed orthodontic appliances. Samples and Methods: Forty-five patients with fixed orthodontic appliances with metallic brackets that have generalized chronic dental plaque-induced gingivitis were selected randomly and divided into three groups - Group I (control), Group II (CMN), and Group III (CHX), respectively. Clinical parameters which are plaque index (PI) and gingival index (GI) were recorded at the baseline, 14 days, and 21 days of treatment, and a total bacterial count test (TBCT) was done for all the participants before and after treatment. Results: Both Curcumin and Chlorhexidine gel groups showed a significant reduction (P&lt;0.05) in PI, GI, and TBCT compared to the control group at the end of treatment (after 21 days). However, there was no significant difference between Curcumin and Chlorhexidine gel groups (P&gt;0.05). Conclusion: The results of this study show that curcumin and chlorhexidine gel have comparable anti-plaque, anti-gingivitis, and antibacterial activities and that both can be used to effectively treat plaque-induced gingivitis.

Study the Effect of a Fixed Orthodontic Appliance on the Oral Microbial Cavity

Background: Orthodontics is that branch of dentistry specialty dealing with diagnosis, prevention, and correction of malocclusion aiming to enhance oral health, dental function, and esthetics. The presence of a fixed orthodontic appliance within the oral cavity can alter the microbial balance and so the composition of dental plaque. However, the presence of a fixed appliance alters the physiological characteristics of the oral cavity, causing impaired hygiene, a raise in dental plaque collection, and a delay in the spontaneous physiological processes of tooth cleaning that result in pathogenic bacteria colonization, which causes gingival inflammation, periodontal support degradation, and enamel surface alterations. Objective: The study’s objectives were isolated, identification, and molecular detection of microbes associated with orthodontic appliance patients. Materials and Methods: A total of 88 study samples (68 case; 20 control), 29 males and 59 females, aged 14–35 years, underwent fixed orthodontics during the initial stage of treatment. The samples were cultured on enrichment media and selective media, including mitis-salivarius agar, Mitis-Salivarius Bacitracin agar, Lactobacillus MRS agar, Eosin Methylene Blue agar, and Mannitol agar. They cultured in aerobic and anaerobic (10% CO2) conditions. Results: The positive samples were then purified and identified using morphological and biochemical tests. Among the microbial species gram-positive bacteria accounted for 82.3%, gram-negative bacteria 16.2%, and fungi 1.5%. Our results show that on one hand, gram-positive bacteria, Streptococcus mutans make higher percentage (48.5%) compared to other types. On the other hand, the Escherichia coli with 11.7% is the highest percentage of gram-negative bacteria. Conclusion: Bacteria colonization of orthodontic patients was found to be remarkably high compared to that of controls. Finally, the most common bacteria are S. mutans identify using PCR utilizing Sm.479.F/R primer combination.

Clinical Performance Evaluation of a Hyaluronic Acid Dental Gel for the Treatment of Traumatic Ulcers in Patients with Fixed Orthodontic Appliances: A Randomized Controlled Trial.

A newly available gel containing hyaluronic acid (HA) and polyvinylpyrrolidone was tested for efficacy on traumatic oral ulcers (TOU) caused by fixed orthodontic appliances. A double-blind RCT was conducted to test the new gel versus a placebo. According to the sample size calculation, a total of 60 patients were considered sufficient and randomly allocated to one of the two groups out of a pool of 100 total patients who initially agreed to participate in the study. A VAS scale test and lesion measurements at T0, T1, and T2 were performed on the patients. A total of 70 patients developed TOU, with 8 drop-outs; the intergroup comparison showed a statistically significant greater dimension of the lesion in the control group at T2 when compared to the test group. The pain experienced by the patients belonging to the test group was significantly lower than the pain in the patients in the control group Conclusions: Under the limitations of the study, the new formula might provide faster healing with less pain experienced by the patient when compared to a placebo.

Sequelae of Unreplaced Tooth Loss in Orthodontic Patients: A Cross-Sectional Study in Najran, Kingdom of Saudi Arabia.

The early tooth loss has an adverse effect on the overall well-being of an individual. The aim of the current study was to highlight the orthodontic complications of long-term tooth loss in the city of Najran. This was a cohort study of patients presenting for orthodontic rehabilitation. A total of 326 patients that presented for orthodontic rehabilitation were examined clinically and data such as age, gender, number of missing teeth, missing teeth, duration of missing teeth, tipping, and overerupted and rotated teeth were recorded. Patients that can be treated with orthodontic space closure were excluded from the study. Patients' data were analyzed using IBM SPSS Statistics and results were presented as simple frequencies and descriptive statistics. Out of 326 patients that presented for orthodontic rehabilitation, 259 patients had missing teeth with its sequelae that will demand prosthodontic rehabilitation with a prevalence rate of 79.4%. There are 97 (37.5%) males and 162 (62.5%) females with M:F ratio of 1:1.7. The age ranged from 15 to 52 years with mean ± standard deviation (28.5 ± 8.5). The age group 21-30 years constitutes the group with the highest number of missing teeth. A total number of 595 (60.2%) teeth were missing, 173 (17.5%) teeth were tipped, and 124 (12.5%) teeth were overerupted, whereas only 97 (9.8%) teeth were rotated (n = 989). Fixed orthodontic appliances (FOAs) were used for all cases with rotation and FOAs + Mini Screws were used for all cases with tipping, overeruption, and/or combinations. The dental loss was managed by prosthesis depending on patients' choice and financial capability ranging from removable/fixed prosthesis and dental implants. Orthodontic consequences of early tooth loss include tipping and rotation of adjacent teeth and overeruption of opposing teeth. Early acknowledgment of tooth replacement after tooth loss is essential in preventing long-term orthodontic adverse effects.