In this work, synthesis of chitosan beads impregnated with nano-γ-Al2O3 (AlCB) was carried out. The characteristics of the synthesized adsorbent were obtained by using Brunauer Emmett and Teller technique and Scanning Electron Microscopy method. The use of AlCB in continuous removal of chromium, lead, nickel and cadmium ions from liquid solution was studied using fixed-bed column system. Bed depths and flow rate effects on breakthrough and uptake capacity of the adsorbent in column were also examined. Dynamic parameters of the adsorption were calculated by using bed depth service time (BDST) and Thomas models. In both models, the data were analyzed by error analyzing and combining the values of determined coefficient (R 2) from regression analysis. The adsorption capacities of AlCB in breakthrough were 158.33, 183.33, 63.33 and 31.67 mg/g for chromium, lead, nickel and cadmium, respectively. In addition, BDST model was found to be an acceptable kinetic model to describe the experimental data.