Fixation Time Research Articles

Impact of various types of provocative advertisements on brand recall and attention engagement: Pilot study report

AbstractThe study's main goal was to investigate the impact of various types of shocking content of provocative advertisements on brand recall and visual attention engagement. The experiment used the eye‐tracker (iViewX RED500) to record the eye movements. Forty‐one participants were divided into two groups. Provocative (drastic, religious, and erotic) advertisements were presented experimental group while the control group was shown modified illustrations without provocative content. The study revealed that the average fixation time and fixation counts on erotic element were significantly higher in provocative advertisements than in their non‐provocative equivalents. Average fixations time on the brand was significantly greater in non‐provocative advertisements than in erotic versions of these ads. It was found that the shocking element and brand were better remembered in provocative advertisements containing religious content than in their non‐provocative equivalents. In contrast, these elements were less remembered in advertisements containing drastic content than in their non‐provocative equivalents.

Hybrid fitness effects modify fixation probabilities of introgressed alleles.

Hybridization is a common occurrence in natural populations, and introgression is a major source of genetic variation. Despite the evolutionary importance of adaptive introgression, classical population genetics theory does not take into account hybrid fitness effects. Specifically, heterosis (i.e. hybrid vigor) and Dobzhansky–Muller incompatibilities influence the fates of introgressed alleles. Here, we explicitly account for polygenic, unlinked hybrid fitness effects when tracking a rare introgressed marker allele. These hybrid fitness effects quickly decay over time due to repeated backcrossing, enabling a separation-of-timescales approach. Using diffusion and branching process theory in combination with computer simulations, we formalize the intuition behind how hybrid fitness effects affect introgressed alleles. We find that hybrid fitness effects can significantly hinder or boost the fixation probability of introgressed alleles, depending on the relative strength of heterosis and Dobzhansky–Muller incompatibilities effects. We show that the inclusion of a correction factor (α, representing the compounded effects of hybrid fitness effects over time) into classic population genetics theory yields accurate fixation probabilities. Despite having a strong impact on the probability of fixation, hybrid fitness effects only subtly change the distribution of fitness effects of introgressed alleles that reach fixation. Although strong Dobzhansky–Muller incompatibility effects may expedite the loss of introgressed alleles, fixation times are largely unchanged by hybrid fitness effects.

A Video-Based, Eye-Tracking Study to Investigate the Effect of eHMI Modalities and Locations on Pedestrian–Automated Vehicle Interaction

Numerous studies have emerged on the external human–machine interface (eHMI) to facilitate the communication between automated vehicles (AVs) and other road users. However, it remains to be determined which eHMI modality and location are proper for the pedestrian–AV interaction. Therefore, a video-based, eye-tracking study was performed to investigate how pedestrians responded to AVs with eHMIs in different modalities (flashing text, smiley, light band, sweeping pedestrian icon, arrow, and light bar) and locations (grill, windshield, and roof). Moreover, the effects of pedestrian-related factors (e.g., gender, sensation-seeking level, and traffic accident involvement) were also included and evaluated. The dependent variables included pedestrians’ clarity-rating scores towards these eHMI concepts, road-crossing decision time, and gaze-based metrics (e.g., fixation counts, dwell time, and first fixation duration). The results showed that the text, icon, and arrow-based eHMIs resulted in the shortest decision time, highest clarity scores, and centralized visual attention. The light strip-based eHMIs yielded no significant decrease in decision time yet longer fixation time, indicating difficulties in comprehension of their meaning without learning. The eHMI location had no effect on pedestrians’ decision time but a substantial influence on their visual searching strategy, with a roof eHMI contradicting pedestrians’ inherent scanning pattern. These findings provide implications for the standardized design of future eHMIs.

Martingales and the fixation time of evolutionary graphs with arbitrary dimensionality.

Evolutionary graph theory (EGT) investigates the Moran birth–death process constrained by graphs. Its two principal goals are to find the fixation probability and time for some initial population of mutants on the graph. The fixation probability of graphs has received considerable attention. Less is known about the distribution of fixation time. We derive clean, exact expressions for the full conditional characteristic functions (CCFs) of a close proxy to fixation and extinction times. That proxy is the number of times that the mutant population size changes before fixation or extinction. We derive these CCFs from a product martingale that we identify for an evolutionary graph with any number of partitions. The existence of that martingale only requires that the connections between those partitions are of a certain type. Our results are the first expressions for the CCFs of any proxy to fixation time on a graph with any number of partitions. The parameter dependence of our CCFs is explicit, so we can explore how they depend on graph structure. Martingales are a powerful approach to study principal problems of EGT. Their applicability is invariant to the number of partitions in a graph, so we can study entire families of graphs simultaneously.

In-Hospital Morbidity and Mortality With Delays in Femoral Shaft Fracture Fixation.

To investigate trends in the timing of femur fracture fixation in trauma centers in the United States, identify predictors for delayed treatment, and analyze the association of timing of fixation with in-hospital morbidity and mortality using data from the National Trauma Data Bank. Patients with femoral shaft fractures treated from 2007 to 2015 were identified from the National Trauma Data Bank and grouped by timing of femur fixation: <24, 24-48 hours, and >48 hours after hospital presentation. The primary outcome measure was in-hospital postoperative mortality rate. Secondary outcomes included complication rates, hospital length of stay (LOS), days spent in the intensive care unit LOS (ICU LOS), and days on a ventilator. Among the 108,825 unilateral femoral shaft fractures identified, 74.2% was fixed within 24 hours, 16.5% between 24 and 48 hours, and 9.4% >48 hours. The mortality rate was 1.6% overall for the group. When fixation was delayed >48 hours, patients were at risk of significantly higher mortality rate [odds ratio (OR) 3.60; 95% confidence interval (CI), 3.13-4.14], longer LOS (OR 2.14; CI 2.06-2.22), longer intensive care unit LOS (OR 3.92; CI 3.66-4.20), more days on a ventilator (OR 5.38; CI 4.89-5.91), and more postoperative complications (OR 2.05; CI 1.94-2.17; P < 0.0001). Our study confirms that delayed fixation of femoral shaft fractures is associated with increased patient morbidity and mortality. Patients who underwent fixation >48 hours after presentation were at the greatest risk of increased morbidity and mortality. Although some patients require optimization/resuscitation before fracture fixation, efforts should be made to expedite operative fixation. Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.

Surgical Management of Distal Clavicle Fractures in Skeletally Immature Athletes

Background:Distal clavicle fractures account for a significant proportion of clavicle fractures in the pediatric and adolescent age groups, but clinical decision making to date has largely been informed by adult studies. However, surgical treatment in this younger population may have unique technical and clinical considerations, due to distinct fracture patterns, increased healing potential and periosteal thickness.Hypothesis/Purpose:The objective of this study was to characterize distal clavicle fractures in a cohort of pediatric and adolescent athletes who underwent operative treatment at a single, tertiary-care pediatric center, including surgical techniques used and resultant clinical outcomes.Methods:A retrospective review was performed of all operatively-treated clavicle fractures extending to the coracoclavicular ligaments or lateral, between 2005-2020. Patients >19 years-old or those with pathological fractures were excluded. Radiographic characteristics, surgical fixation construct, time to radiographic healing, return to sports, and complications were analyzed.Results:Fifty-two patients were identified, with mean age 13.8 ± 2.2 years. The majority of fractures were classified as Nenopoulus type IIB (transverse, displaced; 42.3%) or type IIIB (oblique, displaced; 26.9%), with type IIA (transverse, minor displacement; 3.8%), IV (comminuted; 11.6%) , and V (AC dislocation; 15.4%) patterns also observed. Primary direction of displacement was posterior in 90% of cases and superior in 10%. Plate fixation was performed in 53.8% of surgeries, with locking plate (26.9%) and hook plate (17.3%) most frequent. Suture-based fixation was performed in 32.7% of cases (Figure 1). Rate of removal of implants was 66% after plate fixation, the majority of which (72.2%) were planned at the time of primary fixation. Patient age was comparable in suture and plate cohorts (12.9 vs. 13.5, p = 0.19). Total complication rate, including unplanned removal of implants, was higher in the plate fixation group (25%) than in the suture-based fixation group (11.2%). Time to radiographic healing was not significantly different between plate and suture-based constructs (2.9 vs. 2.9 months, p = 0.96) though patients with suture-based constructs returned to sport faster (2.5 vs. 3.6 months, p = 0.014).Conclusion:The vast majority of distal clavicle fractures treated operatively in pediatric and adolescent athletes are posteriorly displaced fractures. When chosen in the appropriate patient, suture-only constructs can lead to similar healing and faster return to sports compared to plate-based constructs, with greatly reduced need for removal of hardware. These data provide a foundation for future comparative research further elucidating precise surgical indications and optimal treatment approaches.Table 1.Fixation Methods for Distal Clavicle Fractures

Paper 12: Biomechanical Comparison of Anatomic Restoration of the Ulnar Footprint Versus Traditional Ulnar Tunnels in Ulnar Collateral Ligament Reconstruction

Objectives:Current techniques for ulnar collateral ligament (UCL) do not reproduce the anatomic ulnar footprint of the UCL. The purpose of this study was to describe a novel UCL reconstruction technique that utilizes proximal-to-distal ulnar bone tunnels to better recreate the anatomy of the UCL and compare the biomechanical profile at time zero between this technique, the native UCL, and the traditional docking technique. Our hypothesis was that the biomechanical profile of the anatomic technique is similar to the native UCL and traditional docking technique.Methods:Ten matched cadaveric elbows were potted with the forearm in neutral rotation. The palmaris longus tendon graft was harvested, and bones were sectioned 14 cm proximal and distal to the elbow joint. Specimen testing included: (1) native UCL testing performed at 90° flexion with 0.5 Nm valgus moment preload, (2) cyclic loading from 0.5-to-5 Nm valgus moment for 1000 cycles at 1 Hz, and (3) load to failure at 0.2 mm/s. Elbows then underwent UCL reconstruction with one elbow of each pair receiving the classic docking technique using either anatomic (proximal-to-distal) or traditional (anterior-to-posterior) tunnel locations. Specimen testing was then repeated, as described above.Results:There was no difference between maximum load at failure or valgus angle between the anatomic or traditional tunnel location techniques (34.90 ± 10.65 Nm vs. 37.28 ± 14.26 Nm, P = 0.644) or the native UCL (45.83 ± 17.03 Nm, P = 0.099). Additionally, there was no difference in valgus angle after 1000 cycles across the anatomic (4.58 ± 1.47°), traditional (4.08 ± 1.28°), or native UCL (4.07 ± 1.99°). Anatomic group and the native UCL had similar valgus angles at failure (24.13 ± 5.86° vs. 20.13 ± 5.70°, P = 0.083), while the traditional group had a higher valgus angle at failure compared to the native UCL (24.88 ± 6.18° vs. 19.44 ± 5.86°, P = 0.015).Conclusions:UCL reconstruction with the docking technique utilizing proximal-to-distal ulnar tunnels to restore the anatomic ulnar footprint better recreates the anatomy of the UCL while providing valgus stability comparable to reconstruction with docking technique using traditional anterior-to-posterior ulnar tunnel locations. These results suggest that utilization of the anatomic tunnel location in UCL reconstruction has similar biomechanical properties compared to the traditional method at the time of initial fixation (i.e., not accounting for healing following reconstruction in vivo) while keeping the ulnar tunnels further from the ulnar nerve. Further studies are warranted to determine if an anatomically based UCL reconstruction results in differing outcomes compared to traditional reconstruction techniques.

Application of special exercises to develop the fixation time and the skills of forehand and backhand groundstrokes in tennis players

The present study was conducted on the Misan tennis clubs advanced players, in the premises of the tennis court of the Technical Institute in Misan. The study was conducted within the timeframe of August 2020 to December 2020. In the current study, the research community was represented by the players of the Misan Governorate team. A total of 8 players were selected as the participants for the study. All the participants were randomly allocated into two groups with n=4 in each group. The researcher formulated a set of exercises. These exercises were performed by the participants of the experimental group during their preparation phase and in the main training phase. The control group participants received training by exercises developed by the training coaches. The total number of training exercises was 8. In each training dose 4 exercises were included. In the present study the researchers concluded that there was a positive effect of the special exercises in developing the fixation time during the performance of the forehand and backhand groundstrokes.

Driver's Visual Attention Characteristics and Their Emotional Influencing Mechanism under Different Cognitive Tasks.

The visual attention system is the gateway to the human information processing system, and emotion is an important part of the human perceptual system. In this paper, the driver’s visual attention characteristics and the influences of typical driving emotions on those were explored through analyzing driver’s fixation time and identification accuracy to different visual cognitive tasks during driving. The results showed that: the increasing complexity of the cognitive object led to the improvement of visual identification speed. The memory and recall process increased drivers’ fixation time to cognitive objects, and the recall accuracy decreased with the increase in time interval. The increase in the number of cognitive objects resulted in the driver improving the visual identification speed for the cognitive object at the end of the sequence consciously. The results also showed that: the visual cognitive efficiency was improved in the emotional states of anger and contempt, and was decreased in the emotional states of surprise, fear, anxiety, helplessness and pleasure, and the emotional state of relief had no significant effect on the visual cognitive efficiency. The findings reveal the driver’s visual information processing mechanism to a certain extent, which are of great significance to understand the inner micro-psychology of driver’s cognition.

Can a Fully Articulating Electromechanical Laparoscopic Needle Driver Compare with a Robotic Platform in Transabdominal Preperitoneal Inguinal Hernia Repair?

Background: Enhanced laparoscopic instruments are filling the gap between straight-stick laparoscopic equipment and robotic platforms. We sought to evaluate the performance and cost of the HandX™ device during mesh fixation and peritoneal flap closure of transabdominal preperitoneal (TAPP) inguinal hernia repairs. Methods: The video recordings of a consecutive series of TAPP surgeries using the articulated needle driver device were compared with a series of surgeries on the DaVinci robotic platform by a single surgeon. Two critical steps of the procedure were analyzed: mesh fixation and peritoneal closure. A cost analysis between the two platforms was completed. Results: We analyzed 27 cases using the new needle driver and 27 cases using the DaVinci Surgical Robotic system. To evaluate the learning curve (LC) with the HandX device, we created three groups (G1, G2, and G3). The two latter groups were combined and called after LC. Mean fixation time using the DaVinci system was 258.1 seconds (±100.4) compared with 391.5 (±95.9) using the articulating handheld laparoscopic needle driver after LC (P < .001). The average time for peritoneal closure was 418.6 (±192.1) seconds for DaVinci and 634.5 (±159.5) seconds for HandX (P < .001). When comparing the after-LC HandX cases and the DaVinci system stratified by side, there was no significant difference in peritoneal closure in the right side (520.1 seconds (84.3) with the HandX versus 444.2 seconds (229.7) using the DaVinci system (P = .353). When evaluating direct cost of the instruments, HandX cases had a lower cost (310 USD) when compared with the cost of using DaVinci (973 USD). Conclusions: The new smart articulating needle driver may be a cost-effective means of bringing some of the benefits of the robotic platform to laparoscopy.

Compression devices for temporary hemostasis in injuries of the abdomen and adjacent ileo‑inguinal areas (literature review)

The review analyzes the available literature on the experimental justification and experience of practical application of existing promising devices for stopping intra‑abdominal and external bleeding in the ilio‑inguinal regions by creating an external local compression. Objective : to analyze the order of application, effectiveness and parameters of safe use of “abdominal tourniquet” for local compression of the abdomen and ilio‑inguinal areas with continued bleeding into the peritoneal cavity and pelvic tissue, damage to the vessels of the ilio‑femoral segment, as well as with high hip detachments, when it is impossible to fix the classic tourniquet. Materials and methods. The analysis of modern domestic and foreign literature, the sacred relevance of the pathology under consideration, the constructive features of the main models of devices for creating external compression in the abdomen and adjacent areas of the body, the experience and results of their application in laboratory and real conditions is carried out. Results. The obtained data allow us to assert that today the following four models belong to the main products of the above‑described purpose: AAJT (Abdominal Aortic and Junctional Tourniquet), CRoC (Combat Ready Clamp), JETT (Junctional Emergency Treatment Tool), SJT (SAM Junctional Tourniquet). The considered devices for creating local compression provide temporary hemostasis in intra‑abdominal bleeding, injury of large vessels of the ilio‑inguinal regions and high separation of the thighs, but their use has a number of features that affect the effectiveness of stopping blood flow. Conclusion. The considered compression devices have design features and limitations, so when creating a domestic analog, additional data on the algorithm of use is needed, depending on the area of the wound and the intended source of bleeding, the timing of fixation, as well as the possible combination of this method of temporary hemostasis with other promising methods of stopping bleeding at the pre‑hospital stage.

Prediction of Human-Computer Interaction Intention Based on Eye Movement and Electroencephalograph Characteristics.

In order to solve the problem of unsmooth and inefficient human-computer interaction process in the information age, a method for human-computer interaction intention prediction based on electroencephalograph (EEG) signals and eye movement signals is proposed. This approach is different from previous methods where researchers predict using data from human-computer interaction and a single physiological signal. This method uses the eye movements and EEG signals that clearly characterized the interaction intention as the prediction basis. In addition, this approach is not only tested with multiple human-computer interaction intentions, but also takes into account the operator in different cognitive states. The experimental results show that this method has some advantages over the methods proposed by other researchers. In Experiment 1, using the eye movement signal fixation point abscissa Position X (PX), fixation point ordinate Position Y (PY), and saccade amplitude (SA) to judge the interaction intention, the accuracy reached 92%, In experiment 2, only relying on the pupil diameter, pupil size (PS) and fixed time, fixed time (FD) of eye movement signals can not achieve higher accuracy of the operator’s cognitive state, so EEG signals are added. The cognitive state was identified separately by combining the screened EEG parameters Rα/β with the eye movement signal pupil diameter and fixation time, with an accuracy of 91.67%. The experimental combination of eye movement and EEG signal features can be used to predict the operator’s interaction intention and cognitive state.

The Kocher-Langenbeck approach combined with robot-aided percutaneous anterior column screw fixation for transverse-oriented acetabular fractures: a retrospective study

ObjectiveTransverse-oriented acetabular fractures (TOAFs), including transverse, transverse with posterior wall and T-shaped fractures, are always challenging for double-column reduction and fixation with minimally invasive method. The purpose of this study is to compare the therapeutic effects of robot-aided percutaneous anterior column screw fixation versus minimally invasive anterior plate fixation for TOAFs based on the Kocher-Langenbeck (K-L) approach.MethodsPatients suffering TOAFs that were fixed by robot-aided percutaneous anterior column screw fixation or minimally invasive anterior plate fixation associated with posterior fixation via the K-L approach were divided into two groups: group A (screw fixation) and group B (plate fixation). Surgical time, blood loss, incision length for anterior fixation and complications were recorded. Fracture reduction quality was evaluated using criteria described by Matta. Fracture healing was assessed on the series of pelvic radiographs at each follow-up. Functional outcomes were investigated using the modified Postel Merle D’Aubigne score at the final follow-up.ResultsTwenty-nine patients with TOAFs, including 12 patients in group A and 17 patients in group B, were evaluated for study eligibility. The mean surgical time of anterior fracture fixation was 18.7 ± 4.6 min in group A and 33.4 ± 5.0 min in group B (P < 0.001). The amount of intraoperative blood loss was 615.6 ± 178.7 ml in group A and 719.3 ± 199.0 ml in group B (P < 0.001). Incision length for anterior fixation was 9.0 ± 1.8 mm in group A and 81.2 ± 7.3 mm in group B (P < 0.001). The complications related to the surgery of anterior column only occurred in group B (lateral femoral cutaneous nerve palsy in 1 patient and groin discomfort in 1 patient). No significant differences in reduction quality, hospital stay, fracture healing time and functional results were noted between the two groups.ConclusionThe K-L approach combined with robot-aided anterior column screw fixation is a safe and effective option for TOAFs. Compared with minimally invasive anterior plate fixation, robot-aided screw fixation has obvious advantages on surgical time, blood loss, and invasiveness. The K-L approach combined with minimally invasive anterior plate fixation can also be a reliable alternative for TOAFs, with the similar reduction quality and functional results.

Acute shortening and re-lengthening versus antibiotic calcium sulfate-loaded bone transport for the management of large segmental tibial defects after trauma

BackgroundThe purpose of this paper was to compare the clinical effects of acute shortening and re-lengthening (ASR) technique with antibiotic calcium sulfate-loaded bone transport (ACSBT) technique for the management of large segmental tibial defects after trauma.MethodsIn this retrospective study, 68 patients with large segmental tibial defects were included and completely followed. The bone loss was 3–10 cm. ASR group included 32 patients, while ACSBT group contained 36. There was no significant difference in demographic information between the two groups. The external fixation time (EFT) and external fixation index (EFI) were compared. Bone defect healing and limb functions were evaluated according to the Association for the Study and Application of the Method of Ilizarov (ASAMI) criteria. Complications were compared by Paley classification.ResultsThe mean EFT was 9.2 ± 1.8 months in ASR group and 10.1 ± 2.0 months in ACSBT group, respectively. The mean EFI was 1.5 ± 0.2 month/cm and 1.4 ± 0.3 month/cm. According to the ASAMI criteria, in ASR group bone defect healing was excellent in 22 cases, good in 7 cases and fair in 3 cases. In ACSBT group, it was excellent in 23 cases, good in 11 cases and fair in 2 cases. In ASR group, the limb function was excellent in 15 cases, good in 7 cases and fair in 10 cases, while it was excellent in 14 cases, good in 9 cases and fair in 13 cases with ACSBT group. There was no significant difference in EFI, bone defect healing and limb functions between the two groups (p > 0.05). The mean number of complications per patient in ACSBT group was significantly lower than that in ASR group (p < 0.05).ConclusionBoth techniques can be successfully used for the management of large segmental tibial defects after trauma. There was no significant difference in EFI, limb functions and bone defect healing between the two groups. Compared with ASR group, the complication incidence in ACSBT group was lower, especially the infection-related complications. Therefore, for patients with large segmental bone defects caused by infection or osteomyelitis, ACSBT technique could be the first choice.

Retrospective clinical outcomes in the definitive treatment of high-energy tibial diaphyseal fractures using hexapod external fixator versus monolateral external fixator

BackgroundExternal fixation, which can preserve the biomechanical microenvironment of fracture healing, plays an important role in managing the high-energy fractures with poor surrounding soft tissues. The purpose of this study was to determine the differences of clinical outcomes, if any, between hexapod external fixator and monolateral external fixator in the definitive treatment of high-energy tibial diaphyseal fractures.MethodsA total of 53 patients with high-energy tibial diaphyseal fractures and definitively treated by the hexapod external fixator (HEF) or monolateral external fixator (MEF) were retrospectively collected and analyzed, from March 2015 to June 2019. There were 31 patients in the HEF treatment, and the other 22 patients were managed by the MEF. The demographic data, surgical duration, external fixation time, final radiological results, complications, and clinical outcomes were documented and analyzed. Difficulties that occurred during the treatment were classified according to Paley. The clinical outcomes were evaluated by the Association for the Study and Application of the Method of Ilizarov criteria (ASAMI) at the last clinical visit.ResultsThe mean surgical duration in the HEF group (62.4 ± 8.3 min) was shorter than that in the MEF group (91.4 ± 6.9 min) (P < 0.05). All patients acquired complete bone union finally. Patients in the HEF group (24.2 ± 3.1 weeks) underwent a shorter average external fixation time than that in the MEF group (26.3 ± 3.8 weeks) (P < 0.05). Satisfactory alignment was achieved in all patients without the need for remanipulation. The residual sagittal plane deformities in the HEF group were all less than that in the MEF group (P < 0.05). The complication rate was 35.5% in the HEF group, while 45.5% in the MEF group. There was no statistically significant difference between the two groups in ASAMI scores (P > 0.05).ConclusionThere is no statistically significant difference in finally clinical outcomes between hexapod external fixator and monolateral external fixator in the definitive treatment of high-energy tibial diaphyseal fractures. The hexapod external fixation treatment is a superior effective method, including advantages of stable fixation, less surgical duration, postoperatively satisfactory fracture reduction, and fewer complications.

A Study of Surgical Management of Floating Knee in Adults

&#x0D; &#x0D; Background: Floating knee injury is a term used to denote ipsilateral femoral and tibial metaphyseal injuries. But recent literature has however expanded this term to include most ipsilateral fractures of the femur and tibia. These areextremely heterogeneous groups of injuries. They usually occur due to very high energy trauma. These are relativelyuncommon injuries. These are always associated with high morbidity. Most of these injuries result in some permanent disability. There are no specific guidelines for the management. The implant choice needs to be determined depending onnature of fracture and soft tissue injuries.&#x0D; Material and Methods: This study is about the Functional Outcome of Surgical Managements of Floating Knee For this study 17 consecutive patients with ipsilateral femur and tibia fractures, All cases of ipsilateral tibia and femur fractures were included. Study duration of two years. Detailed history will be obtained using Performa with special attention to mechanism of injury. Evaluations including base line clinical features. Examination of other associated symptoms will bebased on history and physical examination. The plan of management for the given patient was made depending on the nature of fracture, location of fracture, associated soft tissue injuries. &#x0D; Conclusion: Patients who undergo primary nailing will have Excellent or Good results. The most important factors which determine the functional outcomes were the type of fractures (open or closed), nature of comminution including intraarticular extensions, timing of fixations and post operative infections. &#x0D; &#x0D; &#x0D; Keywords: Floating knee; primary nailing, intraarticular extension, comminution, metaphysic.

Differences between inexperienced and experienced safety supervisors in identifying construction hazards: Seeking insights for training the inexperienced

The hazard identification ability of frontline safety supervisors is essential to ensure site safety. As experience can benefit the identification performance, this study investigates the gaps between inexperienced and experienced safety supervisors. Thirty-five experienced safety supervisors and 35 novices were invited to identify hazards in 18 virtual construction sites created by 360-degree panoramas. Their identification results, attention allocation, and adopted scanpaths during the identification process were compared. It is found that the experienced significantly spent more fixation time, had more fixations, and gave a larger proportion of attention to hazardous areas. In contrast, the inexperienced had no idea about where might exist hazards in a scenario. They missed hazards due to ignoring the hazardous areas. Besides, it was hard for the inexperienced to recognize hazards requiring in-depth knowledge of safety regulations. They significantly identified fewer hazards except for the relatively obvious hazards: improper use of PPE and struck-by hazards. The scanpaths were more consistent among the experienced. They observed the scene sequentially, without consciously adopting any specific searching patterns from which the novices could learn. Therefore, it is suggested to train the inexperienced to be aware of hazardous areas in workplaces in addition to educating them on safety norms; and provide them chances to practice hazard identification to retain their learned knowledge. The findings reveal the gaps between inexperienced and experienced safety supervisors, providing insights for training the inexperienced and thus helping ensure the job site safety.

The Defender's Vision-Gaze Behavior of One-on-One Defenders in Basketball.

In fast-paced team sports, anticipation is one important element in defense strategies. The primary objective of this study was to examine the recommendation for action and use of defensive gaze strategies by defensive players in basketball. Four national-level expert-basketball coaches were interviewed and a field study with mobile eye-tracking devices was conducted on 16 expert and 16 novice players defending in a one-on-one situation. Differences in relative fixation times between experts and novices were elaborated for the predetermined gaze zones-head, ball, torso, and feet-as given by the expert coaches. This was done for three phases of the movement sequence: receiving, dribbling, and shooting. The results of the interviews with expert coaches indicated that the existing coaching doctrine instructs players to look at the torso of an opponent to avoid being vulnerable to fakes. Surprisingly, our findings with the players showed a discrepancy in the evaluated gaze behavior of the experts and novices. For the receiving and dribbling phase, experts mainly fixated their gaze on the head while novices focused on the ball. For the final shooting phase, both the groups mainly fixated their gaze on the ball. Fixating the gaze on the ball or head makes the player potentially vulnerable to deceptive movements, as video-based research has shown. Expert coaches also indicated that peripheral vision is of importance to defenders, contradicting the existing assumption in the literature that focusing on the task-relevant areas is key for anticipation performance.

Interactive Computer Thresholding of Central Acuity under Conditions of Contrast and Luminance Simulating Real World Environments: Evaluation of the Effects of Aging and Optical Correction

Purpose: The Central Vision Analyzer (CVA) is an interactive computer device that has been reported to measure functional resolution at fixation under contrast and luminance conditions and fixation times which mimic a number of vision tasks of day and evening activities. The program presents Landolt C’s that are flashed at fixation for 250 msec and tumbled 1 of 4 directions; the program thresholds for the smallest C the position of which is correctly recognized. In sequential fashion, the CVA tests 3 mesopic environments (98% Michelson Contrast, MC, against a background of 1.6 cd/m2, 25% MC against 5 cd/m2, then 50% MC against 1.6 cd/m2) and 3 glare environments (98%, 10% and 8% MC, all against a background of 220 cd/m2). This report evaluates the impact of aging and optical correction method on the resolution acuity measured in normal eyes.

The effect of prolonged formalin fixation on the expression of proteins in human brain tissues

Formalin-fixed, paraffin-embedded (FFPE) tissues have been widely used in researches. Proteins and nucleic acids in prolonged FFPE tissues display different degrees of degradation. We investigated the effect of prolonged formalin fixation on protein expression in human brain tissues. Twenty-eight middle prefrontal front cortex tissue blocks from human brains prefixed in formalin were obtained from a brain bank. The tissue blocks were divided into two groups, the control group and the prolonged fixation group. Quantitative immunocytochemistry was used to analyse the biological markers of Fox-3, Rbfox3 (NeuN), glial fibrillary acidic protein (GFAP), ionized calcium binding adapter molecule-1 (IBA-1) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH). Nissl staining showed that positive signaling of Nissl body was significantly decreased by 16.6% in the prolonged fixation group. In addition, the staining intensity of Nissl body was negatively correlated with fixation time. The level of NeuN immunoreactivity (ir) was significantly reduced by 19.31% in the prolonged fixation group. Moreover, there was a significant negative correlation between NeuN-ir and fixation time. There were no significant changes in GFAP-ir, IBA-1-ir and GAPDH-ir between control group and the prolonged fixation group. Prolonged formalin-fixed tissues showed time- and molecule-dependent protein changes, which may be potential confounders in the clinic and researches. Our study suggested short formalin fixation time is recommended when using PPFE brain tissues.