Introduction: Proximal humerus fractures are amongst the most common upper extremity fractures that are found in elderly as well as young age groups. Although majority of them are treated conservatively, due to the demand for early return to the daily activities and problems of late collapse/ displacement with conservative measures there arise a need for plate ostesynthesis. Amongst the various methods of fixation, Proximal humerus intrlocking plates designs promise an opportunity to minimize the common complicsations. However, a gap still exists between in vitro results and clinical outcomes. Addressing to the limitations and need to evaluate the efficacy of the currently available proximal humerual interlocking plates, the purpose of this study will be to evaluate the short and medium term functional resultys with fixation of proximal humerus fracture and review the common complications associated. Materials and methods: In this prospective observational study, conducted at a tertiary care centre, patients from 18-85 age group were selected according to the inclusion and exclusion criteria.