Abstract Introduction Given the rise of digital health applications and direct-to-consumer (DTC) testosterone platforms, testosterone-related mobile applications (apps) pose significant challenges for both consumers and healthcare professionals. Objective The purpose of this study is to investigate trends and characterize the landscape of currently offered testosterone-related mobile health applications. Methods A search query of the term “testosterone” was conducted on the Apple app store. A comprehensive analysis of 23 testosterone-related apps was conducted, evaluating them based on categorization, primary service, specific health topics addressed, release years, cost model, user ratings, and evidence base. Apps were also evaluated on an established misinformation index score from one to five, whereby a score of five indicated complete accuracy and one, complete inaccuracy. Results Most apps were categorized as Health and Fitness apps, focused on sexual performance optimization, and addressed specific testosterone-related issues. A marked 600% increase in app releases were observed from 2020-22 when compared to prior to 2018. Apps frequently claimed to improve testosterone-related issues, but few cited scientific literature, resulting in a mean misinformation index score of 3.0. Conclusions The findings highlight the urgent need for healthcare professionals' active involvement in guiding patients through the digital health landscape. It is crucial to establish guidelines that ensure the provision of accurate, evidence-based information in health apps. Further research should focus on assessing the real-world impact of these apps on patient outcomes and developing strategies to mitigate digital health misinformation risks. Disclosure No.