A case of an abscess in the root of the mesenterium and a case of a rectovesicular fistula, caused by fishbone penetration out of the intestinal tract, are reported. In addition, 121 previously reported cases of fishbone penetration out of the intestinal tract in Japan were reviewed. This condition has most commonly occurred in persons between 40 and 60 years old, and the male/female ratio is 3 to 1. In examining the length of the penetrating fishbone, rather small ones, ranging from 2.0 to 2.5cm showed the highest incidence. The clinical pictures as well as the produced lesions varied; therefore accurate preoperative diagnosis was difficult. Clinical courses such as those in the present cases have not been reported. Penetration appeared to occur anywhere in the gastrointestinal tract, preferably in the lower intestinal tract. It has long been believed that these penetrations were often at the site of physiological stricture or fixed intestine, which could not be confirmed in this review. The presence of a solid stool may be responsible for the frequent occurrence in the lower intestinal tract. For accurate pre-operative diagnosis of this disease, a careful barium X-ray examination is recommended.