This paper continues the study that began in [1,2] of the Cauchy problem for ( x , t ) ∈ R N × R + for three higher-order degenerate quasilinear partial differential equations (PDEs), as basic models, u t = ( − 1 ) m + 1 Δ m ( | u | n u ) + | u | n u , u t t = ( − 1 ) m + 1 Δ m ( | u | n u ) + | u | n u , u t = ( − 1 ) m + 1 [ Δ m ( | u | n u ) ] x 1 + ( | u | n u ) x 1 , where n > 0 is a fixed exponent and Δ m is the ( m ≥ 2 ) th iteration of the Laplacian. A diverse class of degenerate PDEs from various areas of applications of three types: parabolic, hyperbolic, and nonlinear dispersion, is dealt with. General local, global, and blow-up features of such PDEs are studied on the basis of their blow-up similarity or traveling wave (for the last one) solutions. In [1,2], the Lusternik–Schnirel’man category theory of variational calculus and fibering methods were applied. The case m = 2 and n > 0 was studied in greater detail analytically and numerically. Here, more attention is paid to a combination of a Cartesian approximation and fibering to get new compactly supported similarity patterns. Using numerics, such compactly supported solutions are constructed for m = 3 and for higher orders. The “smother” case of negative n < 0 is included, with a typical “fast diffusion–absorption” parabolic PDE: u t = ( − 1 ) m + 1 Δ m ( | u | n u ) − | u | n u , where n ∈ ( − 1 , 0 ) , which admits finite-time extinction rather than blow-up. Finally, a homotopy approach is developed for some kind of classification of various patterns obtained by variational and other methods. Using a variety of analytic, variational, qualitative, and numerical methods allows us to justify that the above PDEs admit an infinite countable set of countable families of compactly supported blow-up (extinction) or traveling wave solutions.