QCD bounds on the leading-order (LO) hadronic vacuum polarization (HVP) contribution to the anomalous magnetic moment of the muon [aμHVP,LO, aμ=(g−2)μ/2] are determined by imposing Hölder inequalities and related inequality constraints on systems of finite-energy QCD sum rules. This novel methodology is complementary to lattice QCD and data-driven approaches to determining aμHVP,LO. For the light-quark (u, d, s) contributions up to five-loop order in perturbation theory in the chiral limit, LO in light-quark mass corrections, next-to-leading order in dimension-four QCD condensates, and to LO in dimension-six QCD condensates, we find that (657.0±34.8)×10−10≤aμHVP,LO≤(788.4±41.8)×10−10, bridging the range between lattice QCD and data-driven values. Published by the American Physical Society 2024