Introduction: Fine needle aspiration cytology (FNAC) is slightly invasive, cost effective and gold standard for thyroid nodule diagnosis. Aim: The aim of the study is to correlate the pre-operative and post-operative findings of FNAC with histopathology and detect pitfills of FNAC. Materials and methods: The study is retrospective and consists of about 100 cases which were recruited from department of pathology, GEMS & Hospital for a period of September 2017 to February 2019. The available cases from department were considered for the study. Fine needle aspiration results were compared with histological diagnosis. Observation and results: FNAC diagnosis showed benign lesions in 86 patients, malignant in 14 patients and histopathological findings exhibited benign in 88 and malignant in 7 cases. Sensitivity, specificity and accuracy of the study to diagnose malignant lesions were calculated and are 75%, 98% and 98.3% respectively. Conclusion: FNAC has evolved as most accurate, sensitive and specific tool for screening of thyroid patients initially and hence minimized the takeover of un-necessary surgeries. However, histopathological diagnosis remains to be confirmatory.