Abstract Downstream vortex generators that involve a pair of rectangular plates arranged in an open V-shape placed just downstream of each film-cooling hole were shown to create flow and vortical structures that entrain lifted film-cooling flow back to the surface and increase its lateral spreading on the surface (GT2020–14317). In this study, computations and measurements were performed to examine the flow mechanisms this vortex generator induces to improve film-cooling effectiveness of a flat plate with the cooling flow emanating from one row of inclined holes. Parameters studied include blowing ratio (BR = 0.75 and 1.0) and temperature ratio (TR = 1.07 and 1.9). The computational study is based on steady Reynolds-averaged Navier–Stokes (RANS) closed by the shear-stress transport (SST) turbulence model with and without conjugate analysis. The experimental study was conducted by using a conjugate heat transfer test rig with a plenum, where cooling flow is introduced. Measurements made include velocity and temperature profiles upstream and downstream of the film-cooling holes as well as the temperature at several locations on the hot and cold sides of the film-cooled flat plate. The computational study was validated by comparing computed results with those from measurements at BR = 0.75 and 1.0 and TR = 1.9. Computational and experimental results are presented to show the effects of BR and TR on the flow structures and how those structures improve the effectiveness of film cooling with and without the downstream vortex generators and with and without conjugate heat transfer.