Filiform Papillae Research Articles

Antillean manatee (Trichechus manatus manatus Linnaeus, 1758) Tongue Morphology and Adaptive Herbivorous Implications.

Morphological study of the tongue is an interesting way of understanding evolutionary processes associated with feeding habits. Therefore, the aim of the present study was to describe the tongue morphology of the Antillean manatee and to understand possible morphological relationships with its way of capturing food. Macroscopic dissections and light and scanning electron microscopy analyses of seven manatee tongues were performed. The tongue in Antillean manatees is a muscular and robust organ, divided into apex, body, and root. It is firmly adhered to the floor of the oral cavity. Lingual papillae were distributed over the entire tongue surface. They were identified as filiform papillae concentrated in the apex. Fungiform papillae were present on the apex and lateral regions. Foliate papillae were located on the dorsolateral portion of the root. Lentiform papillae were located across the dorsal tongue surface. The mucosa was lined by a keratinized stratified squamous epithelium presenting compound tubuloacinar glands and taste buds in the foliate papillae. The tongue of the Antillean manatee is similar to other Sirenia species, both of which share a completely herbivorous diet.

Lingual Ultrastructural and Histochemical Study in the Patagonian Mara (Rodentia: Caviidae, Dolichotis patagonum) in Relation to Other Hystricomorphs.

The study describes the ultrastructure of the tongue in the Patagonian mara (Dolichotis patagonum) using light and scanning electron microscopy. Histochemical methods were used for evaluation of lingual salivary glands. The tongue is divided into a small and rounded apex, a narrow corpus, and a significantly wider radix, with a well-developed lingual prominence. The tip of the apex is free of papillae. The caudal part of the apex and the corpus are covered by filiform papillae. Round fungiform papillae are scattered among them. Papillae on the narrow stalk are conical. The radix contains caudally bent papillae forming wide flat prominences, slender, hook shaped filiform papillae, foliate papillae, and two oval vallate papillae. Taste buds were found on the lateral sides of the foliate and vallate papillae. Purely serous salivary glands are beneath the vallate and foliate papillae. Serous acini and mucous tubules are in the lingual radix. The Patagonian mara is the only hystricomorph rodent with described hyaline cartilage strengthening the lingual radix. Some typical signs of adaptation to herbivorous diet were found. The structure of the tongue is adapted to grass-feeding, as grasses form the main component of their diet.

Machine learning and topological data analysis identify unique features of human papillae in 3D scans

The tongue surface houses a range of papillae that are integral to the mechanics and chemistry of taste and textural sensation. Although gustatory function of papillae is well investigated, the uniqueness of papillae within and across individuals remains elusive. Here, we present the first machine learning framework on 3D microscopic scans of human papillae (n=2092\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$n=2092$$\\end{document}), uncovering the uniqueness of geometric and topological features of papillae. The finer differences in shapes of papillae are investigated computationally based on a number of features derived from discrete differential geometry and computational topology. Interpretable machine learning techniques show that persistent homology features of the papillae shape are the most effective in predicting the biological variables. Models trained on these features with small volumes of data samples predict the type of papillae with an accuracy of 85%. The papillae type classification models can map the spatial arrangement of filiform and fungiform papillae on a surface. Remarkably, the papillae are found to be distinctive across individuals and an individual can be identified with an accuracy of 48% among the 15 participants from a single papillae. Collectively, this is the first evidence demonstrating that tongue papillae can serve as a unique identifier, and inspires a new research direction for food preferences and oral diagnostics.

Development of the Goose Tongue Filiform Papillae: Could it be Tooth-Like Sense Organs?

Development of the Goose Tongue Filiform Papillae: Could it be Tooth-Like Sense Organs?

Geographic tongue: What is this disease?

Geographic tongue or benign migratory glossitis, is a unique and peculiar tongue condition, producing a map-like appearance with filiform papillae atrophy, on different parts of the tongue. The lesions change in shape with time. The exact etiology remains unknown, although it has been suggested relating the lingual microbiota of a patient. The association between geographictongue and psoriasis has long been pointed out, and histological similarities existed between both as well. Increasingly, recent findings suggest the involvement of certain oral bacteria. Here, we discuss these findings with an overview of the recent literature.

Tongue of the Egyptian Endemic Bridled Skink (Heremites vittatus; Olivier, 1804): Gross, Electron Microscopy, Histochemistry, and Immunohistochemical Analysis.

The present study used light and scanning electron microscopy to describe the integrative morphological description of the tongue and laryngeal mound of Heremites vittatus, an endemic lizard of Saharan Africa. Additionally, ultrastructure, histology, histochemistry, and immunohistochemical approaches were used to characterize the lingual apparatus adaptations. In the present study, Heremites vittatus consisted of a complex lingual papillary system in which the ventral apical surface of the foretongue comprised conical papillae. The dorsal surface consisted of different filiform papillary (papillae filiformes) types: the anterior section had two types (bifid and pointed), and the posterior section had four types (triangular, trifid, quadrifid, and pentafid) papillae. The dorsal midtongue surface exhibits scale-like, serrated filiform papillae with anterior gland openings. The hindtongue consisted of two overlapping filiform papillae: scale-like, board-serrated papillae on the median portion and finger-like papillae on the wings. The dorsal surface of the laryngeal mound had 18 longitudinal folds with glandular openings. Histologically, the foretongue was covered by a slightly keratinized layer that was absent in the mid- and hindtongue. The lingual glands were absent from the foretongue but present in the interpapillary space in the mid- and hindtongues. We observed a few rounded taste buds in the conical papilla epithelium. Histochemical analysis revealed strong glandular Alcian Blue (AB)-positive and Periodic Acid-Schiff (PAS)-positive reactions. Immunohistochemistry showed strong cytokeratin immunopositivity in all parts of the tongue. In conclusion, the obtained data about the lingual characterizations have been consistent with the active foraging behavior of the species and its environmental conditions.

A Comparative Histological And Histochemical Study Of The Tongue Of Local Adult Ducks And Geese

Our study aimed to determine the histological and histochemical composition of the tongue of both ducks (Anas Platyrhynchos) and geese (Anserini). Our histological study showed that the mucous membrane covering the tongue in local ducks and geese consists of a multi-layered epithelium covering the lamina propria, which differs in the degree of keratinization according to its location in the tongue, and that the thickness of the epithelium of the dorsal surface of the tongue gradually decreases from the front towards the root, while the epithelium increases in thickness towards the root. The ossified epithelium is located at the top and beginning of the body of the tongue, forming what is known as the nail of the tongue in both ducks and geese. The small and large conical papillae in various parts of the tongue, as well as the filiform papillae, are covered with erosive ossified epithelium

Pantoprazole induced black hairy tongue: a case report

Black hairy tongue (BHT) is characterized by abnormally hypertrophied and elongated filiform papillae, appearing as blackish discoloration on the dorsal surface of the tongue. BHT has been reported as an adverse drug reaction to different categories of drugs. However, pantoprazole induced BHT has been rarely reported. We present the case of a 42-year-old female, admitted in the surgery ward with postoperative wound infection, for which she was prescribed oral clarithromycin and pantoprazole. On the third day of starting medications, she complained of blackish discoloration on the dorsal surface of the tongue with an alteration of taste sensation, which was clinically and microscopically diagnosed as BHT. Suspecting BHT as an adverse drug reaction to pantoprazole, it was stopped, while clarithromycin was continued for the full course. She was also advised to scrape her tongue thrice daily, drink adequate fluids and maintain good oral hygiene. On the third day after stopping pantoprazole, black discoloration and alteration of taste sensation resolved completely. WHO-UMC causality assessment scale showed a ‘probable’ association of the adverse drug reaction with pantoprazole. Physicians should be aware of the possibility of BHT with the use of pantoprazole and that it completely resolves on stoppage of the drug, mechanical debridement and good oral hygiene.

A morphological investigation of the tongue of roe deer (Capreolus capreolus Linnaeus, 1758).

The morphological structure of the tongue and papillae that occur on it vary according to an animal's lifestyle, nutrition, and adaptation to various environmental conditions. This study aimed to reveal in detail the morphological, histological, and electron microscopic structure of the tongue of roe deer (Capreolus capreolus Linnaeus, 1758). In this study, nine roe tongues were used. The tongue consists of three parts: the apex, body, and root. When the dorsal surface of the tongue was examined in detail, five different papillae were observed: filiform, lenticular, conical, fungiform, and vallate. Filiform papillae differed in having secondary papillae according to their localization. The opening holes of taste buds were observed on the surface of the round and flat fungiform papillae. The free ends of the filiform papillae were more pointed and thinner than those of the other papillae, while the width of the lenticular papillae was thicker, the surface was flat, and the free ends were blunt. Triangular-shaped conical papillae were observed differently regarding the presence or absence of secondary papillae. The vallate papillae were caudolateral to the lingual torus. On the surface of the vallate papillae, circumferenced by a deep groove, were the opening holes of the taste buds and microridges. From this analysis, it appears to be characteristic of roe deer that mechanical function, filiform, and conical papillae contain secondary papillae; lenticular papillae, absent in many deer species, are found; and a prominent papillary groove surrounds all mechanical and gustatory papillae. RESEARCH HIGHLIGHTS: The lingual papillae of roe deer (Capreolus capreolus Linnaeus, 1758) were examined with this study in detail for the first time. Similarities and differences with ruminant species were determined.

The tongue morphology of Pteropus vampyrus from Timor Island, Indonesia: New insights from scanning electron and light microscopic studies

Abstract. Selan YN, Wihadmadyatami H, Haryanto A, Kusindarta DL. 2023. The tongue morphology of Pteropus vampyrus from Timor Island, Indonesia: New insights from scanning electron and light microscopic studies. Biodiversitas 24: 3512-3518. The large flying fox (Pteropus vampyrus Linnaeus, 1758) is a Southeast Asian megabat species includes with frugivorous bats. The tongue plays a pivotal role in taking, chewing, and swallowing food. The structure of the bat tongue hampers considerable variation, mainly in the papilla. Variations occur owing to the feeding habits, environment, and adaptation of bats to their environments. The aim of this study was to clarify the morphological structure of the tongue of P. vampyrus obtained from the island of Timor, East Nusa Tenggara, Indonesia, by using Scanning Electron Microscope (SEM) and Light Microscopy(LM). This study included six adult bats regardless of sex. Macroscopically, the tongue of P. vampyrus consists of three parts: the apex, corpus, and radix. SEM and LM confirmed that the apex presents filiform papillae of several subtypes, including scale-like filiform, giant trifid, and small crown-like papillae. In addition, the apex features fungiform and transitional papillae between the giant trifid and small crown-like papillae. Furthermore, the corpus consists of filiform papillae (leaf-like filiform and large crown-like papillae) and fungiform papillae. The radix consists of filiform papillae (long conical, leaf-like filiform, and short conical papillae), fungiform papillae, and three V-shaped circumvallate papillae pointing to the larynx.

Novel oral microscope gives mechanistic insights into colloidal drivers of friction in oral biofilms

Texture and mouthfeel are central to the sensory enjoyment of food and beverages. Yet our incomplete understanding of how food boluses are transformed in the mouth limits our texture prediction ability. As well as thin film tribology, the interaction of food colloids with the oral tissue and salivary biofilms plays a key role in texture perception via mechanoreceptors in the papillae. In this study we describe the development of an oral microscope capable of quantitative characterization of the inactions of food colloids with papillae and their concurrent saliva biofilm. We also highlight how the oral microscope revealed key microstructural drivers of several topical phenomena (oral residue formation, coalescence in-mouth, grittiness of protein aggregates and finally microstructural origin of polyphenol astringency) in the domain of texture creation.The coupling of a fluorescent food grade dye with image analysis enabled specific and quantitative determination of the microstructural changes in mouth. Emulsions either underwent no aggregation, small aggregation, or extensive aggregation depending on whether their surface charge facilitated complexation with the saliva biofilm. Quite surprisingly cationic gelatin emulsions that were already aggregated with saliva in mouth underwent coalescence if subsequently exposed to tea polyphenols (EGCG). Large protein aggregates were found to aggregate with the saliva coated papillae, increasing their size tenfold and possibly explaining why there are perceived as gritty. An exciting observation was the oral microstructural changes that occurred upon exposure to tea polyphenols (EGCG). Filiform papillae shrunk, and the saliva biofilm was seen to precipitate/collapse, exposing a very rough tissue surface. These tentative early steps are the first in vivo microstructural insights into the different food oral transformations that are drivers of key texture sensation.

Morphological identification of the squirrel (Callosciurus notatus) tongue through Scanning Electron Microscopy (SEM) and histochemistry

Abstract. Megawati EI, Pradipta SID, Damia U, Kustiati U, Wihadmadyatami H, Kusindarta DL. 2023. Morphological identification of the squirrel (Callosciurus notatus) tongue through Scanning Electron Microscopy (SEM) and histochemistry. Biodiversitas 24: 2302-2314. Squirrel (Callosciurus notatus) plays an important role in the agricultural ecosystem.Their urine and feces kill coconut tree pests and help preserve coconut farming productivity. This research focuses on the morphological identification of the tongue and lingual papillae distribution of the Callosciurus notatus’stongue. The tongue morphology and lingual papillae distribution of Callosciurus notatus were investigated through two different methods: using scanning electron microscopy (SEM) and histology. This paper provides macroscopic and histological tongue morphology and lingual papillae distribution of Callosciurus notatus. Macroscopically, the tongue is divided into the apex, corpus, and radix. The dorsal surface of the apex the groove and lateral prominence were occur. SEM and light microscopy observation showed that the apex bears three types of papillae: leaf-like filiform, bifid filiform, and fungiform. The corpus includes wide leaf-like filiform papillae, saw-like filiform papillae, bifid filiform papillae, and fungiform papillae. On the radix, there are conical like filiform papillae, fungiform papillae, conical and vallatae papillae. The lateral part of radix showed Weber’s glands that react strongly positively by Alcian Blue (AB) pH 2.5 and periodic acid Schiff (PAS) staining; Weber’s glands consist of neutral and acidic mucin. Von Ebner’s glands were at the textus muscularis striatus syncytialis near the vallatae papillae, which react weakly positively to PAS stain and did not react to AB pH 2.5 stain; von Ebner’s glands consist of neutral mucin. Masson Trichromestain revealed collagen structure on lamina propria mucosae and textus muscularis striatus syncytialis of apex; moderately on lamina propria mucosae and lesser on textus muscularis striatus syncytialis of the corpus and radix.

Comparative Studies of the Tongue of Postnatal (Lactating), Young and Adult Between Two Species of Mammalian Animals of Different Feeding Habit Rattus Rattus and Orcytolagus Cuniculus

Background: The study of tongue of mammals is important because the different species of animals with different feeding, so the present study was attended to observe the relation between various feeding and the morphological shape of tongue of present stages of both R. rattus and O. cunniculus using histological, histochemical techniques, ultra structural examination and Statistical analysis. Results: The Egyptian herbivorous rabbit O. cunniculus and the rodent R. rattus showed that the tongue is elongated with rounded apex. In both species the thicknesses of the tongue increase gradually toward the pharynx. The tongue length of adult rabbit was large than the adult rat. In the studied animals, the anterior end of the tongue of the herbivorous rabbit O. cunniculus is covered with short horny filiform papillae at the anterior part and giant circumvallate papilla at the posterior part with taste buds, also large enormous numbers of mucus and serous glands but in the rodent Rattus is covered with short pointed horny filiform papillae and others small elongated ones. Few numbers of fungiform papillae and numbers of mucus and serous glands are scattered among the skeletal muscles. The Tongue of adult R. rattus and O. cunniculus have different shapes of filiform papillae, fungiform papillae distributed between the filiform ones, two circumvallate on the surface, number of serrate glands and mucous gland. Give strong reaction with Periodic Acid Schiff (PAS). In young and lactating some undifferentiated and poor developed papillae were observed and serrate and mucous glands less than that in adult stage Conclusion: The different feeding habit of both rat (rodents and Rabbit (herbivorous) give different shapes of papilla and give different reaction with histochemical stains.

Detection of SARS-CoV-2 and Its Related Factors on the Mucosal Epithelium of the Tongue

SARS-CoV-2 infects a variety of tissues, including the oral cavity. However, there are few reports examining the association of SARS-CoV-2 with tongue mucosal tissues with sticky tongue debris. This study investigated the presence of SARS-CoV-2 and its associated molecules by dissecting tongue tissue from autopsy specimens of 23 patients who died of COVID-19-related illness (pneumonia). Immunohistochemical staining, electron microscopy, and PCR analysis were performed on the tongue tissue specimens. The mucosal epithelium of the tongue formed a very thick keratinized with well-developed filiform papillae in all cases. ACE2 and TMPRSS2 were consistently co-expressed in all samples in the epithelium. The S-protein was strongly expressed in basal cells and the epithelial surface. S-protein-positive viral particles were detected in the tongue's stratified squamous epithelium via an immunoelectron microscope. Based on PCR amplification of the N1 and N2 regions, the SARS-CoV-2 gene was detected on the tongue epithelium, tongue submucosa, and in tongue debris. This suggests that tongue debris, including the squamous epithelial tissue, could be a source of SARS-CoV-2 in saliva. Furthermore, removing tongue debris may decrease the amount of SARS-CoV-2 in the oral cavity.

Clinical atrophy patterns of filiform papillae of the tongue and their relationship with the serum levels of iron, vitamin B12 and folic acid in patients with systemic diseases.

The purpose of the study was to evaluate the clinical patterns of atrophy of the filiform papillae (FP) of the tongue and their relationship with the serum levels of iron and vitamin B12 among patients with systemic diseases, in a tertiary care center. A cross-sectional, analytical, research study was designed. A systematic tongue examination was performed to evaluate the presence and clinical patterns of FP atrophy. We collected epidemiologic, clinical, and laboratory data. Statistical analysis included χ2 test, Fisher's exact test, Kruskal-Wallis test, and a logistic regression analysis. A total of 87 patients (83.9% females) were included [median age = 55 (range 20-89) years]. Endocrinopathy (60.9%) was the most frequent comorbidity. We found atrophy of the FP in 90.8% of the patients; the atrophy was mild in 83.5% of the cases, and severe in 16.5%. The most common atrophic patterns were as follows: focalized in 64 (73.6%) cases, "U"-shaped pattern in 60 (69%), and generalized in 30 (34.5%). Geographic tongue and median rhomboid glossitis were observed in 12 (13.8%) and 11 (12.6%) subjects, respectively. Lower titers of serum iron were detected in cases with focal (median = 71 vs. 110 mcg/dl) and generalized (median = 55 vs. 78 mcg/dl) FP atrophy (P = 0.03 and P = 0.009, respectively), than their counterparts. The presence of symptomatology was related to the focal pattern of atrophy (P = 0.038). A high frequency of filiform papillary atrophy of the tongue was observed in patients with comorbidities. Some atrophic patterns of the tongue were significantly associated with certain medical conditions.

Comparative Study of Lingual Papillae, Lingual Glands and Lyssa of the Tongue of Selected Wild Felids (Carnivora, Felidae) in Biological Aspects.

Although much attention has been paid in the literature to the morphology of the tongue in various animal species, including some Felidae, it has not yet been described in detail in the vulnerable Neofelis nebulosa and Panthera leo bleyenberghi and the last concern Lynx lynx and Otocolobus manul. Therefore, the present study aimed to characterize the features of the tongue surface, lingual glands and lyssa in the above-mentioned four selected wild species of the Pantherinae and Felinae subfamilies. Macroscopic, histological, histochemical and ultrastructural analyzes were used in the present work. Comparative analyzes of the dorsal tongue surface showed the presence of mechanical lingual papillae on five subtypes of filiform papillae on the apex and body and conical papillae on the root of the tongue. Gustatory papillae in the four analyzed species were fungiform papillae and various numbers of vallate papillae. Foliate papillae were absent in P. leo bleyenberghi and L. lynx, while delicate smooth folds, which were separated by parallel grooves but without taste buds, were present in N. nebulosa. The vallate and foliate papillae were accompanied by lingual glands, which produced a serous secretion, whereas the mixed lingual glands of the lingual root were with a predominance of mucus secretions comparable to four captive Felidae species. In the median plane on the ventral surface of the apex under its epithelium and within the muscle fibers, the lyssa was also observed to a varying degree, with the least developed, and thought about the size of the entire tongue, was in P. leo bleyenberghi. The lyssa structure in the four species was dominated by adipose tissue. The obtained results contribute knowledge concerning the functional anatomy of the tongue in four selected Felidae species, especially in terms of comparative anatomy.

Lingual morphology ofdomesticated Asian small-clawed otters inYogyakarta, Indonesia.

This study aimed toobserve the lingual morphology ofthe domesticated Asian small-clawed otter, Aonyx cinereus (A.cinereus), from Yogyakarta, Indonesia. Six domesticated A.cinereus adults were obtained from alocal otter breeder inYogyakarta, with noregard tosex. The animals were acclimated tothe laboratory for one day, following this, the animals underwent macroscopy identification and scanning electron microscopy (SEM) and light microscopy (LM) analysis. Macroscopically, the tongue ofdomesticated A.cinereus isdivided into three parts: the apex, corpus, and radix. The apex isthe shortest part and can move freely. Amedian groove isbent along the corpus. Typically, the radix contains circumvallate papillae and the epiglottic valleculae. The SEM and LM observations revealed that the lingual morphology ofA.cinereus consisted oftwo types ofpapillae: mechanical papillae (horny filiform, leaf-like filiform, bifid filiform, trifid filiform, elongated leaf-like filiform, triangular filiform and conical papillae) and gustatory papillae (fungiform and circumvallate papillae). The lingual glands consisted ofWeber's glands and von Ebner's glands secreting acid and neutral mucins. Collagen fibres are found inthe lamina propria and muscular layer. Inconclusion, the papillae ofthe Asian short-clawed otter have the same structure asthose ofother Mustelidae family members.

Scanning electron microscopic characterizations of the tongue of the Nubian goat (Capra aegagrus hircus): A specialized focus on its papillary system adaptation to Egyptian environmental conditions.

The current investigation was focused on describing the gross and scanning electron features of the Nubian goat (Capra aegagrus hircus) tongue, with new insights into its papillary adaptation to the Egyptian environment. The elongated tongue had a rostral free and the caudal fixed. The ventral apical surface is classified into the smaller rostral papillary region on the tip and the larger non-papillary region by the U-line of filiform papillae. Functionally, there are two papillary types: mechanical (filiform, conical and lentiform in addition to the longitudinal row of large conical papilla on the lateral of the body) and gustatory (fungiform and circumvallate). Filiform papillae were densely distributed on the dorsal surface of the apex and body, and on the lateral apical border and lateral surface of the body and root, in addition to the ventral surface of the tip. This filiform papillary system gives a raspy appearance to the dorsal surface. The conical and lentiform papillae were limited to the torus linguae. Circumvallate papillae are surrounded by an annular groove and slightly vallum. The lingual root was devoid of any papillae. Lingual papillary subtypes are filiform papillae (elongated and triangular), conical papillae (elongated and oval) and fungiform papillae (round and ovoid). The investigated Nubian goat may have developed a specialized papillary system due to regional differences in the distribution, structure and subtypes of the system, allowing it to adapt to the dried grasses and leaves of trees and bushes that are available in Upper Egypt's dry, hot climate.

Stripping mechanism and Gaussian distribution model of a concave bionic comb for stripping prior to cutting

Stripping prior to cutting is a harvesting technique that only strips rice grains and obtains complete straws. This paper aims to solve the problems of high loss rate and short throwing distance for stripping prior to cutting. A concave bionic comb was developed based on the filiform papilla structure on the surface of a cattle tongue tip. The mechanism analysis and comparative research of the flat comb and the bionic comb were carried out. The results showed that when the arc radius was 5.0 mm, the magnification ratio of filiform papilla was 4.0, and the concave angle was 60°, the loss rate of falling grain was 4.3 %, and the loss rate of uncombed grain was 2.8 %. The diffusion angle of bionic comb was smaller than that of flat comb. The distribution characteristics of the thrown materials conformed to Gaussian distribution. Under the same working conditions, the falling grain loss rate and uncombed loss rate of the bionic comb were always lower than that of the flat comb. This study provides reference for the cross application of bionic technology and crop production field, promotes the harvesting way application of stripping prior to cutting in gramineous plants such as rice, wheat and sorghum, and provides a basis for harvesting the whole straws and expanding the way of comprehensive utilization of straws.

Diode Laser in the Treatment of FoliatePapillitis

The tongue consists of various kinds of papillae which forms its characteristic morphology. These are the filiform papillae, the fungiform papillae, the circumvallate, and the foliate papillae. The foliate papillae may become enlarged and inflamed causing a condition called asFoliate Papillitis. The treatment of this disease includes relieving all causes of trauma to the region. We present a new modality of treatment for this condition by using diode laser of 980nm. Here we report on two patients with foliate papillitis. Both these patients were treated conservatively but experienced only temporary relief from pain. We used diode laser of 980 nm for their treatment and they experienced significant reduction in their pain levels. Since there is not much published literature on Foliate Papillitis or on use of lasers to treat this condition, this is being presented as an alternative treatment for patients who have foliate papillitis and do not get relief from conservative methods. At one year follow-up, both the patients were free of symptoms. We believe this is the first time that diode laser has been used for the treatment of foliate papillitis. Diode laser appears to be a good alternative treatment modality for the treatment for patients with foliate papillitis.