Effect Of Field Size Research Articles

More milkweed in farmlands containing small, annual crop fields and many hedgerows

Milkweed has declined substantially, with over 80% declines in some agricultural regions. This threatens monarch butterfly (Danaus plexippus) persistence, because monarch larvae feed solely on milkweed. Thus conservation actions are needed to enhance the availability of milkweed, particularly in agricultural landscapes. Conservation actions to date have largely focused on reducing intensive agricultural practices, mainly use of herbicides. However, research suggests that landscape-scale alteration of the cropped portion of an agricultural landscape (the "farmland"), for example, to reduce crop field sizes, can benefit herbaceous plants such as milkweed. Here we collected data on milkweed occurrence and cover in agricultural landscapes in Ontario, Canada, capturing variability in milkweed from field edge to interior by sampling in the interior and along the edges of 68 crop fields. We used these data to evaluate the relative effects of farming practices within the sampled field (e.g. herbicide, fertilizer use) on milkweed versus the effects of mean field size, crop diversity, hedgerow cover, and the proportion of farmland in annual crops in the surrounding landscape. Additionally, we evaluated the effects of these variables on the cover of other herbaceous plants, to identify which—if any—could benefit milkweed without increasing overall weed cover. We found more milkweed at sites surrounded by landscapes with smaller crop fields, lower crop diversity, and higher cover of annual crops. Milkweed was more likely to occur at sites surrounded by landscapes with more hedgerows. These landscape-scale effects on milkweed were often larger than those of within-field farming practices. Importantly, we found that most variables had opposite effects on milkweed relative to other plants. Thus, altering the landscape to benefit milkweed does not imply an increase in weed cover.

Subjective measurement of the Stiles-Crawford effect with different field sizes.

The Stiles-Crawford effect of the first kind (SCE) is the phenomenon in which light entering the eye near the center of the pupil appears brighter than light entering near the edge. Previous investigations have found an increase in the directionality (steepness) of the effect as the testing location moves from the center of the visual field to parafoveal positions, but the effect of central field size has not been considered. The influence of field size on the SCE was investigated using a uniaxial Maxwellian system in which stimulus presentation was controlled by an active-matrix liquid crystal display. SCE directionality increased as field size increased from 0.5° to 4.7° diameter, although this was noted in four mild myopes and not in two emmetropes. The change with field size was supported by a geometric optics absorption model.

Effect of Field Size on the Clinical Exposure Index for Lumbar Spine X-ray Examination

Effect of Field Size on the Clinical Exposure Index for Lumbar Spine X-ray Examination

History of whole pelvis plus para-aortic radiation is a risk factor associated with febrile neutropenia during chemotherapy for recurrent cervical cancer.

Radiation-based therapy is widely used for advanced cervical cancer. Prior radiation-based therapy is a potential risk factor for febrile neutropenia (FN). However, the effect of irradiation field size on the incidence of FN during recurrent cervical cancer treatment is unclear. This study aimed to investigate the relationship between prior irradiation field size and FN development during recurrent chemotherapy. This retrospective, observational study included cervical cancer patients who received recurrent chemotherapy between November 2006 and June 2020. The patients were classified into two groups based on the area of irradiation fields. The first group included patients with a history of whole pelvis (WP) irradiation (WP group). The second group had patients who underwent WP plus para-aortic lymph node (PAN) irradiation (WP + PAN group). The incidences of hematological toxicities and FN during the recurrent chemoradiotherapy were compared between the two groups. The FN incidence was significantly higher in the WP + PAN group than in the WP group (32.1% vs. 0%, P < 0.001). The incidence of Grade 4 neutropenia was not significantly different between the WP + PAN and WP groups. The nadir absolute neutrophil counts were significantly lower and the dose reduction or discontinuation rate of chemotherapy was significantly higher in the WP + PAN group than in the WP group. History of WP plus PAN radiation is a risk factor for developing FN during recurrent cervical cancer chemotherapy.

Field size effects on DNA damage and proliferation in normal human cell populations irradiated with X-ray microbeams

To clarify the health risks of internal radiation exposure, it is important to investigate the radiological effects of local exposure at cell levels from radioactive materials taken up by organs. Focusing on the response of cell populations post-irradiation, X-ray microbeams are very effective at reproducing the effects of local exposure within an internal exposure in vitro. The present study aims to clarify the effects of local exposure by investigating the response of normal human cell (MRC-5) populations irradiated with X-ray microbeams of different beam sizes to DNA damage. The populations of MRC-5 were locally irradiated with X-ray microbeams of 1 Gy at 0.02–1.89 mm2 field sizes, and analyzed whether the number of 53BP1 foci as DSB (DNA double strand break) per cell changed with the field size. We found that even at the same dose, the number of DSB per cell increased depending on the X-irradiated field size on the cell population. This result indicated that DNA damage repair of X-irradiated cells might be enhanced in small size fields surrounded by non-irradiated cells. This study suggests that X-irradiated cells received some signal (a rescue signal) from surrounding non-irradiated cells may be involved in the response of cell populations post-irradiation.

On the Optical Stark Effect of Excitons in InGaAs Prolate Ellipsoidal Quantum Dots

In this paper, we study the exciton absorption spectra in InGaAs prolate ellipsoidal quantum dots when a strong pump laser resonant with electron quantized levels is active. Our obtained results by renormalized wavefunction theory show that, under suitable conditions, the initial exciton absorption peak is split into two new peaks as the evidence of the existence of the three-level optical Stark effect of excitons. We have suggested an explanation of the origin of the effect as well as investigating the effect of pump field energy, size, and geometric shape of the quantum dots on effect characteristics. The comparison with the results obtained in the spherical quantum dots implies the important role of geometric shape of the quantum structures when we examine this effect.

Optical properties of spherical quantum dot in the presence of donor impurity under the magnetic field

In this study, the binding energies of an on-center and off-center hydrogenic donor impurity in a spherical quantum dot with finite confinement potential under an applied external magnetic field are investigated in detail by using the matrix diagonalization method in the effective mass approximation. Depending on the calculated energies and wave functions, the linear, third-order nonlinear and total optical absorption coefficients between the ground and several excited states are examined by the iterative method in the compact density matrix approximation for the two-level system. The combined effect of donor position, magnetic field and dot size on binding energies and optical absorption coefficients is observed. The results show that these effects cause significant changes on donor binding energy and optical absorption coefficients.

Assessment of skin doses in small field radiotherapy for 6 MV photons and beam spectral analysis at skin surface: an EGSnrc based Monte Carlo study.

This study aims at the estimation of skin doses during small field radiotherapy with 6 MV photons and analysis of beam spectra at skin surface. The EGSnrc Monte Carlo code was used for spectral analysis and dose scoring in a water phantom. Percent skin dose (PSD) was calculated at a depth of 70µm (relative to 10cm depth), and the effects of field size, collimation, source-to-surface distance, and tissue inhomogeneity (bone/air) below the skin were evaluated. Low-energy photons and contaminant electrons from the machine head or back-scattered from underlying tissue were found to be the major contributors to skin dose. As the field size was reduced, the beam hardened, while the photon and electron fluences at the skin decreased compared to those at the reference depth of 10cm. This resulted in a PSD reduction for fields smaller than the reference field size. Multi leaf collimators increased the PSD (up to 4%) while variation in source-to-skin dose showed a negligible effect. A substantial increase in PSD has been observed (up to 6%) when high Z material like bone was placed below the skin. In contrast, air as underlying material decreased the skin dose. The skin dose varied considerably with various clinical and geometric parameters. It is concluded that, although the skin doses were low for small fields compared to those for the reference field, skin doses may become substantial when escalated target doses are delivered with multi leaf collimators. Moreover, the presence of high Z materials such as bones or metallic implants below the skin can result in significant enhancement of the skin dose.

Assessment of Precise Land Levelling on Surface Irrigation Development. Impacts on Maize Water Productivity and Economics

The new technologies of surface irrigation require the adoption of effective Laser-controlled precision land levelling (PLL) to reach the high irrigation performance standards, with significant benefits on water saving, salinity control, crop productivity, and farmer’s income. This study aimed to assess the performance and the impacts of PLL on surface irrigation systems, focusing the maize crop on the irrigation districts Hetao (China) and Lower-Mondego (Portugal). The experimental study at field scale assessed the PLL and evaluated the on-farm irrigation under precise levelled fields and well management practices. PLL operators have been inquired to improve the knowledge about hiring services. The design of surface irrigation scenarios allowed to explain the effects of field size and slope on irrigation and land levelling performance. The best practice to manage the PLL maintenance is an important issue to guarantee a high effectiveness of irrigation performance. The optimization of PLL appeals the application of best soil tillage practices and the monitoring of soil surface elevations with newest information technologies. Efficient operational guidelines to support the PLL planning, schedule, and operation, well trained operators and carefully adjusted equipment, are key factors to the improvement.

The Effect of Radiation Field Size on Lymphocyte Count and Survival in SBRT Treatment for Head and Neck Cancers

The Effect of Radiation Field Size on Lymphocyte Count and Survival in SBRT Treatment for Head and Neck Cancers

DFD-Net: lung cancer detection from denoised CT scan image using deep learning

The availability of pulmonary nodules in CT scan image of lung does not completely specify cancer. The noise in an image and morphology of nodules, like shape and size has an implicit and complex association with cancer, and thus, a careful analysis should be mandatory on every suspected nodules and the combination of information of every nodule. In this paper, we introduce a “denoising first” two-path convolutional neural network (DFD-Net) to address this complexity. The introduced model is composed of denoising and detection part in an end to end manner. First, a residual learning denoising model (DR-Net) is employed to remove noise during the preprocessing stage. Then, a two-path convolutional neural network which takes the denoised image by DR-Net as an input to detect lung cancer is employed. The two paths focus on the joint integration of local and global features. To this end, each path employs different receptive field size which aids to model local and global dependencies. To further polish our model performance, in different way from the conventional feature concatenation approaches which directly concatenate two sets of features from different CNN layers, we introduce discriminant correlation analysis to concatenate more representative features. Finally, we also propose a retraining technique that allows us to overcome difficulties associated to the image labels imbalance. We found that this type of model easily first reduce noise in an image, balances the receptive field size effect, affords more representative features, and easily adaptable to the inconsistency among nodule shape and size. Our intensive experimental results achieved competitive results.

Arthropod functional traits shaped by landscape-scale field size, local agri-environment schemes and edge effects

Agri-environment scheme (AES) approaches can be classified according to whether they prescribe management in non-productive areas, such as field boundaries and wildflower strips, or in productive areas, such as arable crops. Here we tested the ecological effectiveness of two popular AESs in Germany: wildflower strips next to winter wheat fields as off-field management and organic farming on winter wheat fields as on-field management. We selected ten landscapes along a field size gradient with three focal wheat fields, one conventional field with flower strip, one organic field and one conventional field without flower strip as a control. We sampled arthropods with pitfall traps at field edges and field interiors. We selected three ecological traits for spiders and carabids (body size, feeding trait, dispersal ability). We calculated community weighted mean values (CWM), and we used linear mixed effects models to test the effect of management type and transect position on CWM values. We found pronounced edge effects on most traits, and weaker effects of field size and AES in shaping functional traits. Smaller spiders, spiders with higher ballooning propensity and more web-builders were in the field interior than at the field edge, whereas carnivore carabids preferred field interiors. We also found a strong effect of landscape configuration, i.e. mean field size, as larger field size was positively related to more web-building spiders and more carnivore beetles. Flower strips enhanced populations of web-building spiders. Our results suggest that small-scale agriculture leading to high landscape-scale edge density has a major effect in shaping functional traits and potential ecosystems services in agricultural landscapes. Spider and carabid communities exhibit very different responses to edge vs. interior sites, and, based on the landscape-scale field size gradient emphasize the importance of landscape configuration in shaping the heterogeneity of the arthropods’ traits and presumably ecosystem services in agricultural landscapes.

Beam characteristics of the first clinical 360° rotational single gantry room scanning pencil beam proton treatment system and comparisons against a multi-room system.

PurposeThe purpose of this study was to present the proton beam characteristics of the first clinical single‐room ProBeam Compact™ proton therapy system (SRPT) and comparison against multi‐room ProBeam™ system (MRPT).Materials and MethodsA newly designed SRPT with proton beam energies ranging from 70 to 220 MeV was commissioned in late 2019. Integrated depth doses (IDDs) were scanned using 81.6 mm diameter Bragg peak chambers and normalized by outputs at 15 mm WET and 1.1 RBE offset, following the methodology of TRS 398. The in‐air beam spot profiles were acquired by a planar scintillation device, respectively, at ISO, upper and down streams, fitted with single Gaussian distribution for beam modeling in Eclipse v15.6. The field size effect was adjusted for the best overall accuracy of clinically relevant field QAs. The halo effects at near surface were quantified by a pinpoint ionization chamber. Its major dosimetric characteristics were compared against MRPT comparable beam dataset.ResultsContrast to MRPT, an increased proton straggling in the Bragg peak region was found with widened beam distal falloffs and elevated proximal transmission dose values. Integrated depth doses showed 0.105–0.221 MeV (energy sigma) or 0.30–0.94 mm broader Bragg peak widths (Rb80–Ra80) for 130 MeV or higher energy beams and up to 0.48–0.79 mm extended distal falloffs (Rb20–Rb80). Minor differences were identified in beam spot sizes, spot divergences, proton particles/MU, and field size output effects. High passing scores are reported for independent end‐to‐end dosimetry checks by IROC and for initial 108 field‐specific QAs at 3%/3 mm Gamma index with fields regardless with or without range shifters.ConclusionsThe author highlighted the dosimetry differences in IDDs mainly caused by the shortened beam transport system of SRPT, for which new acceptance criteria were adapted. This report offers a unique reference for future commissioning, beam modeling, planning, and analysis of QA and clinical studies.

The practical radius of a pencil beam in proton therapy

The central Gaussian shaped high dose region of a pencil beam (PB) in light ion beam therapy (LIBT) is enveloped by a low dose region causing non-negligible field size effects and impairs the dose calculation accuracy considerably if the low dose envelope is not well modeled. The purpose of this study was to calculate the practical radius, Rc, at which a PB does not influence a field more than a certain accuracy level.Lateral dose profiles of proton beams in water were simulated using GATE/Geant4. Those lateral dose profiles were integrated numerically and used to calculate field size factors (FSFs). The Rc was then determined such, that the lateral dose at radii exceeding Rc can be neglected without compromising the FSF of a 20cm×20cm field more than a desired accuracy level c. The practical radius Rc yielding c=0.5% was compared to the frequently applied concept of full width at a ratio x of the maximum (FWxM). The sensitivity to variations of the beam width was tested by increasing the initial beam width σC of the clinical beam model by 0.5 and 1mm, respectively.Neglecting the dose at radii exceeding Rc resulted in the desired FSF accuracy, whereas using the FW0.01%M cut resulted in varying accuracy. In order to yield a constant FSF accuracy, the ratio x in FWxM ranged from 0.003% to 0.065% of the maximum. In contrast to Rc, FWxM was sensitive to variations of the initial beam width. The maximum Rc over all depths was less than 7cm for the low(62.4MeV) and medium(148.2MeV) proton energy beam, which suggests that a plane parallel ionization chamber exceeding that radius is sufficient to acquire laterally integrated depth dose distributions for those energies. However, this holds not true for the highest energy (252.7MeV) or when including a range shifter (RaShi). The values of Rc are specific to our beam line configuration as the maximum Rc was depending on both, the scattering material in the Nozzle as well as the distance of the air-gap between Nozzle and phantom.

Postoperative Radiotherapy for Locally Advanced NSCLC: Implications for Shifting to Conformal, High-Risk Fields

BackgroundTo examine the effect of radiotherapy field size on survival outcomes and patterns of recurrence in patients treated with postoperative radiotherapy (PORT) for non–small-cell lung cancer (NSCLC). MethodsWe retrospectively reviewed the records of 216 patients with T1-4 N1-2 NSCLC following surgery and PORT using whole mediastinum (WM) or high-risk (HR) nodal fields from 1998 to 2015. Survival rates were calculated using the Kaplan-Meier method. Univariate and multivariable analyses were conducted using Cox proportional hazards modeling for outcomes and logistic regression analysis for treatment toxicities. ResultsMedian follow-up was 28 months (interquartile range [IQR] 13-75 months) and 38 months (IQR 19-73 months) for WM (n = 131) and HR (n = 84) groups, respectively. Overall survival (OS) was not significantly different between groups (median OS: HR 49 vs. WM 32 months; P = .08). There was no difference in progression-free survival (PFS), freedom from locoregional recurrence (LRR), or freedom from distant metastasis (P > .2 for all). Field size was not associated with OS, PFS, or LRR (P > .40 for all). LRR rates were 20% for HR and 26% for WM groups (P = .30). There was no significant difference in patterns of initial site of LRR between groups (P > .1). WM fields (OR 3.73, P = .001) and concurrent chemotherapy (odds ratio 3.62, P = .001) were associated with grade ≥2 toxicity. ConclusionsLocoregional control and survival rates were similar between PORT groups; an improved toxicity profile was observed in the HR group. Results from an ongoing prospective randomized clinical trial will provide further insight into the consequences of HR PORT fields.

Measurement of Neutron Contamination at Different Points in the Radiotherapy Room

Radyoterapi, kanser tedavisinde kullanılan en önemli tedavi yöntemlerinden birisidir. Ancak, radyoterapide yüksek enerjili foton ve elektron demetlerinin kullanımı sırasında (&amp;gt;7 MV) lineer hızlandırıcı kafasında bulunan ağır metallerden kaynaklı nötron kirliliği oluşmaktadır. Bu durum, hedef hacimde ve çevresindeki diğer organlarda nötron kirliliğinden kaynaklı doz belirsizliğine neden olmakta ve ikincil kanser riski oluşturmaktadır. Bu çalışmada, 18 MV foton enerjisinde, Elekta Synergy lineer hızlandırıcıda Thermo Scientific Rad Eye NL marka nötron dedektörü ile alan açıklığının ve eşmerkeze olan uzaklığın nötron doz hızına olan etkisi incelenmiştir. Ayrıca, alan açıklığının nötron doz hızı üzerindeki etkisi eşmerkezde, eşmerkezden farklı uzaklıklarda, radyoterapi odası kapısının içi ve dışında, konsol odasında ölçümler alınarak araştırılmıştır. Radyoterapide, 18 MV enerjili fotonların neden olduğu nötron kirliliğinden kaynaklı doz belirsizliğinin ikincil kanser riskini artırabileceği öngörülmüştür. Bu nedenle, radyoterapide istenmeyen fotonötron dozunun dikkate alınmasının çok önemli olduğu sonucuna varılmıştır.

The effect of megavoltage field size on intrafraction cone-beam CT image quality.

To investigate the effects of scatter from a megavoltage treatment beam on intrafraction cone beam CT (CBCT) image quality. The effects of treatment beam field size and phantom geometry were investigated as well as the clinical success of IFI. Intrafraction imaging (IFI) was performed on four phantoms with four different MV field sizes using a 6 MV FFF source. The image quality of the intrafraction CBCT images was compared to that of a baseline CBCT (i.e. with no treatment beam on) and quantified using noise and low contrast visibility. Increasing the kV tube current was explored as a possible method to reduce noise induced by the MV photon scatter in the intrafraction-CBCTs. The clinical success of all IFI patients over a 2 month period was reviewed. Intrafraction-CBCT image quality and low-contrast visibility deteriorated as MV field size increased. The extent of image degradation was found to depend on the mass of the phantom resulting in a more pronounced effect for a pelvic phantom than a thoracic phantom. While increasing the tube current could reduce the noise in the intrafraction-CBCT images, increasing the current by a factor of 4 failed to reach baseline image quality. Anatomy was found to be the primary indication of clinical IFI failure with all observed failures occurring during abdominal treatments. Image quality was found to decrease with increasing MV field size and decrease with increasing treatment anatomy mass. When considering intrafraction imaging clinically, the primary indicator of IFI failure is treatment anatomy. IFI can be used during chest treatments with high success rates but care must be taken for abdominal treatments and failures should be expected.

Study on the RBE estimation for carbon beam scanning irradiation using a solid-state microdosimeter.

The purpose of this study was to study the field size effect on the estimated Relative Biological Effectiveness (RBE) for carbon scanning beam irradiation. A silicon-on-insulator (SOI) microdosimeter system developed by the Centre for Medical Radiation Physics, University of Wollongong, Australia, was used for lineal-energy measurements (microdosimetric quantity). The RBE values were derived based on the modified microdosimetric kinetic model (MKM) at different depths in a water phantom in the scanning carbon beam for various scanned areas. Our study shows that the difference in RBE values derived from the SOI microdosimeter measurements with the MKM model and from the Treatment Planning System (TPS). The difference of the RBE values is within 6.5 % at the peak point of the spread-out Bragg Peak (SOBP) region. Compared to the spot-beam, RBE values obtained in the scanned-beam with a larger scanned area of 1.0×1.0cm2 have better agreement with which estimated by the TPS. This study shows the possibility of using the SOI microdosimeter system as a quality assurance (QA) tool for RBE evaluation in carbon-pencil beam scanning radiotherapy.

Does intensive goose grazing affect breeding waders?

Increasing goose population sizes gives rise to conflicts with human socioeconomic interests and in some circumstances conservation interests. Grazing by high abundances of geese in grasslands is postulated to lead to a very short and homogeneous sward height negatively affecting cover for breeding meadow birds and impacting survival of nests and chicks. We studied the effects of spring grazing barnacle geese Branta leucopsis and brent geese Branta bernicla on occupancy of extensively farmed freshwater grasslands by nesting and brood‐rearing waders on the island Mandø in the Danish Wadden Sea. We hypothesized that goose grazing would lead to a shorter grass sward, negatively affecting the field occupancy by territorial/nesting and chick‐rearing waders, particularly species preferring taller vegetation. Goose grazing led to a short grass sward (<5 cm height) over most of the island. To achieve a variation in sward height, we kept geese off certain fields using laser light. We analyzed effects of field size, sward height, mosaic structure of the vegetation, proximity to shrub as cover for potential predators, and elevation above ground water level as a measure of wetness on field occupancy by nesting and chick‐rearing waders. The analysis indicated that the most important factor explaining field occupancy by nesting redshank Tringa totanus, black‐tailed godwit Limosa limosa, oystercatcher Haematopus ostralegus and lapwing Vanellus vanellus as well as by chick‐rearing black‐tailed godwit and lapwing was short vegetation height. Distance to shrub cover and elevation were less important. Hence, despite very intensive goose grazing, we could not detect any negative effect on the field occupancy by nesting nor chick‐rearing waders, including redshank and black‐tailed godwit, which are known to favor longer vegetation to conceal their nests and hide their chicks. Possible negative effects may be buffered by mosaic structures in fields and proximity to taller vegetation along fences and ditches.

A model-based algorithm to correct for the loss of backscatter in superficial X-ray radiation therapy

Dosimetry protocols for superficial X-rays prescribe the determination of kerma on the surface of a phantom through the use of a backscatter factor (Bw) that accounts for the effect of phantom scatter. Bw values corresponding to full-scatter phantoms are provided by these protocols. In practice, clinical situations arise wherein there is insufficient scattering material downstream, resulting in published Bw values that overestimate the amount of occurring scatter.To provide an accurate dose calculation the backscatter values need to be corrected for any reduction in scattered radiation. Estimating the change of Bw in situations with incomplete backscatter has previously been achieved by direct measurements or Monte Carlo modelling. For increasing the accuracy of clinical dosimetries, we developed a physical model to deduce an algorithm for calculating backscatter factors in situations with reduced downstream scattering medium. The predictions of the model were validated by comparison with published data, Monte Carlo simulations and film-based measurements for beams with a half-value layer of 0.8, 2 and 4 mm Al.Our algorithm accurately predicts the effect of partial scatter conditions with suitable precision. Its reliability, combined with the simplicity of calculation, makes this methodology suitable to be incorporated into routine clinical dosimetry. The algorithm’s underlying physical model provides an intuitive understanding of the effects of field size and beam energy on backscatter reduction, permitting a rational management of this effect.