Field Of Health Research Articles

Fatores associados aos distúrbios músculo esqueléticos em trabalhadores da área administrativa em uma instituição de ensino

Introduction: Workers' quality of life is involved in the field of public health, which has been creating spaces for the identification and prevention of work-related diseases, especially musculoskeletal diseases, due to their scope and magnitude. Thus, a study was carried out with the objective of knowing the musculoskeletal symptoms presented by workers in a private institution. Objective: To identify the prevalence and risk factors associated with work-related musculoskeletal disorders. Methods: Data were collected through a cross-sectional study, and a questionnaire was applied to the sample of 62 employees who worked at the institution. The instrument was based on a questionnaire translated and validated for the Portuguese language: the NMQ "Nordic Musculoskeletal Questionnaire". Sociodemographic and occupational characterization variables were collected. The data were analyzed using univariate and multivariate logistic regressions at a significance level of 5%. Results: Among the workers, the following predominated: female; age group from 20 to 30 years old; complete high school; married with children. The highest prevalence of WMSD was in women. The associations found were: non-practitioners of physical activity in the "neck" region (OR 4.98, 95%CI 1.147 – 21.59); and the "wrist and hand" region (OR 6:22; 95%CI 1.5425.15); In the multivariate analysis (multiple logistic regression), the factors associated with pain were: physical activity women also those who did not practice physical activity reported more pain than those who practiced in the neck region 28 employees (73.3%); p= 0.039), with this the association between musculoskeletal symptoms and the variables physical activity and gender was observed. Conclusions: In this context, it can be concluded that there was a prevalence of pain among the professionals studied, and that this has a significant association with several aspects related to work, and some sociodemographic and health factors. In view of the results found, it is necessary to develop and implement strategies to alleviate the workload and avoid problems for these employees.

Association between vitamin D receptor gene polymorphisms and susceptibility to tuberculosis: a systematic review and meta-analysis.

Tuberculosis (TB) is the leading cause of mortality worldwide. Previous studies have reported that TB susceptibility can be caused by vitamin D deficiency, which is affected by polymorphisms in the vitamin D receptor (VDR) gene. However, these results have been inconsistent. Therefore, we performed a meta-analysis to investigate the association between VDR polymorphisms and TB susceptibility. We systematically searched for relevant literature in PubMed, Embase, and Medline databases through December 31st, 2022. Inclusion and exclusion criteria were made to ensure that HIV-negative population is the targeted subjects. The pooled odds ratio (OR) and 95% confidence interval (CI) were then used to assess the strength of the association, and the quality of the included articles was evaluated using the Newcastle-Ottawa Scale. Potential sources of heterogeneity were evaluated based on subgroup and meta-regression analyses. In our meta-analysis, we found that the FokI polymorphism in the VDR gene was associated with increased TB susceptibility in the allele and recessive genotype models (OR f vs. F = 1.235, 95%CI: 1.035-1.475; OR ff vs. Ff + FF = 1.317, 95%CI: 1.005-1.727. Further subgroup analysis based on ethnicity demonstrated the association with the risk of TB in all genotype models of the FokI polymorphism for Han population. Meta-regression analysis also indicated that ethnicity could be a potential source of heterogeneity in the FokI and BsmI polymorphisms in the VDR gene. However, publication year was another source of heterogeneity for the TaqI polymorphism. In summary, the FokI polymorphism in the VDR gene was found to increase the risk of TB in the HIV-negative population, both overall and in Asian populations. The findings presented in this paper could provide clues for preventing TB from the perspective of vitamin D supplementation, which is a controversial topic in the field of medicine and health.

Peer Support Work in the Context of Intimate Partner Violence: A Scoping Review.

Peer support models of service provision have become increasingly prevalent in recent decades across multiple health and human services fields. In this scoping review, we examine peer support work within the context of intimate partner violence (IPV) service provision, including an examination of how this approach is conceptualized, the mechanisms underlying it, the impact of professionalism, and the benefits and challenges experienced by IPV peer support workers (PSWs). Three social science databases were searched with keywords related to IPV and peer support work, with additional articles and materials identified via targeted Google searches. The final sample of materials meeting criteria for the study (i.e., focusing on trained peer workers and their experiences serving IPV survivor clients) includes 10 papers and reports published from 1983 to 2022. We find that peer support work is conceptualized as a holistic alternative to traditional forms of IPV service provision, and that PSWs are viewed as occupying a unique role in relation to clients that enhances their ability to provide comprehensive care. However, we also identify several challenges resulting from the increasing professionalization of the IPV field, including a lack of role clarity for PSWs, a need to balance structure and flexibility in peer work service settings, and skepticism toward PSWs from credentialed professionals. Lastly, we find that although PSWs experience advantages from providing services, including enhanced personal growth and healing, they also navigate challenges related to maintaining their own emotional well-being and would benefit from additional training and institutional support.

Conceptualizing Community Engagement for Mental and Brain Health Research in Low- and Middle-Income Countries: A Case of Kilifi County, Kenya.

Community engagement (CE) has increasingly been recognized as a critical element for successful health promotion and intervention programs. However, the term CE has been used to mean different things in different settings. In this article, we explore how CE has been conceptualized in the field of mental and brain health in Kilifi County, Kenya. We used ethnographic methods encompassing focused group discussions, key informant interviews, and observations with 65 participants, purposively recruited from Kilifi County. Data were transcribed verbatim and thematically analyzed. Our findings show that community members and stakeholders had diverse perceptions of and experiences with CE. Factors such as trust between researchers and community members, sensitization, and awareness creation were key for acceptance of research projects. Partial involvement in research, lack of access to information, poverty and socio-economic challenges, and financial expectations from researchers hindered CE and led to resistance to participation in research projects. For effective CE, there is a need to work closely with community gatekeepers, create awareness of the research projects, use local languages, and ensure continuous engagement that promotes equitable research participation. Our findings suggest that tacit knowledge, context, and mechanisms for research are all critical features of CE and should be considered to enhance acceptance and sustainability of mental and brain health interventions in Kenya.

Assessment of Navy Provider Knowledge of Women's Mental Health Services, Treatment Practices, and Training.

As female active duty populations increase in all military environments, it is critical that women's health be addressed in a comprehensive manner. The study's results will be utilized to assist Navy health care leaders in addressing female force readiness policies, treatment gaps, and training specific to women's mental health. In total, 212 active duty participants were recruited from the Navy's mental health specialties. The survey was hosted on the U.S. Government's MAX.gov survey website and received Institutional Review Board and Survey Review Board approval per Navy and Defense Health Agency requirements. Participants recorded their experiences with various patient presentations using Likert scale assessments, indicated their comfort in prescribing medication to patients with 11 distinct presenting concerns, and responded to six questions regarding their training and clinical experience in the field of women's mental health. Differences were noted for provider gender, treatment setting, patient sex, provider rank, and years of independent practice. Female providers were more likely than males to report that their female patients presented with 15 of the 21 measured issues. Providers located at MTFs were significantly more likely than providers in operational billets to report female patients presenting with certain conditions and reported being more comfortable prescribing medication. Eighty percent of respondents authorized to prescribe medicine rated themselves as very or extremely comfortable prescribing medications to their patients for all specified conditions except two: women who are breastfeeding and women who are pregnant. Senior officers reported the most comfort prescribing medication to women who are planning to become pregnant and women who have experienced perinatal loss. Only a minority of providers (20%, female; 33%, males) reported receiving women's mental health education during their training. Of those who did receive training, it was limited to post-partum and pregnancy. Most participants (93%) agreed that women's mental health should be incorporated into training programs for military providers. This exploratory study highlights that provider variables impact assessment and treatment of and for patients. The study highlights the interplay of gender, treatment setting, experiences, and level of comfort are associated with provider assessment of presenting concerns. The authors hope this study will help in prioritizing women's mental health practices, mental health training, and research, and in informing policy and decision-making.

Simultaneous Effects of Food-related Stresses on the Antibiotic Resistance of Foodborne Salmonella Serotypes

Antibiotic resistance has become one of the most critical issues in the field of public health in recent years. Exposure to food environment stresses may result in the development of antibiotic resistance in Salmonella. The present study aimed to investigate the simultaneous effects of food-related stresses (osmotic pressure, acid, heat, cold, and freezing stresses) on the antibiotic resistance changes in Salmonella Enteritidis and Salmonella Typhimurium. A factorial design with five factors at two levels was used to evaluate the main and interactive effects of stress factors on the antibiotic resistance of Salmonella serotypes. The changes in the antibiotic resistance of Salmonella serotypes were evaluated using the disc diffusion assay. The results showed that the different stresses had different effects on the antibiotic resistance of Salmonella serotypes. The freezing time and osmotic stresses had the most significant effects on the antibiotic resistance (P < 0.05). S. Enteritidis showed the slightest changes after exposure to stresses. The results also showed that a low level (24 h) of freezing time decreased the antibiotic resistance, but at a high level (96 h) increased it. The results emphasized that food processing and storage conditions should be considered as crucial factors in developing antibiotic resistance in Salmonella.

Evaluating the impact of the global evidence, local adaptation (GELA) project for enhancing evidence-informed guideline recommendations for newborn and young child health in three African countries: a mixed-methods protocol

BackgroundPoverty-related diseases (PRD) remain amongst the leading causes of death in children under-5 years in sub-Saharan Africa (SSA). Clinical practice guidelines (CPGs) based on the best available evidence are key to strengthening health systems and helping to enhance equitable health access for children under five. However, the CPG development process is complex and resource-intensive, with substantial scope for improving the process in SSA, which is the goal of the Global Evidence, Local Adaptation (GELA) project. The impact of research on PRD will be maximized through enhancing researchers and decision makers’ capacity to use global research to develop locally relevant CPGs in the field of newborn and child health. The project will be implemented in three SSA countries, Malawi, South Africa and Nigeria, over a 3-year period. This research protocol is for the monitoring and evaluation work package of the project. The aim of this work package is to monitor the various GELA project activities and evaluate the influence these may have on evidence-informed decision-making and guideline adaptation capacities and processes. The specific project activities we will monitor include (1) our ongoing engagement with local stakeholders, (2) their capacity needs and development, (3) their understanding and use of evidence from reviews of qualitative research and, (4) their overall views and experiences of the project.MethodsWe will use a longitudinal, mixed-methods study design, informed by an overarching project Theory of Change. A series of interconnected qualitative and quantitative data collections methods will be used, including knowledge translation tracking sheets and case studies, capacity assessment online surveys, user testing and in-depth interviews, and non-participant observations of project activities. Participants will comprise of project staff, members of the CPG panels and steering committees in Malawi, South Africa and Nigeria, as well as other local stakeholders in these three African countries.DiscussionOngoing monitoring and evaluation will help ensure the relationship between researchers and stakeholders is supported from the project start. This can facilitate achievement of common goals and enable researchers in South Africa, Malawi and Nigeria to make adjustments to project activities to maximize stakeholder engagement and research utilization. Ethical approval has been provided by South African Medical Research Council Human Research Ethics Committee (EC015-7/2022); The College of Medicine Research and Ethics Committee, Malawi (P.07/22/3687); National Health Research Ethics Committee of Nigeria (01/01/2007).

Relationship between Problematic Internet Use and Depression in Young Latin American College Students.

(1) Problematic Internet use (PIU) in young people is a topic of great interest both in the field of addictions and mental health, but scientific evidence is limited in Latin America. The aim was to analyze the relationship between PIU and depression in Latin American college students. (2) Methods: The sample consisted of 1828 college students (63.7% women), aged between 18-30 years (M = 21.64 years). (3) Results: PIU was detected in 40.2% of cases, and severe or moderately severe depression in 31.7%. Rates of severe depression in students with PIU were 3.02 times higher than in those without PIU (χ2(3) = 168.443; p < 0.000). The presence of PIU was also statistically significantly higher among youth with depressive symptoms. Linear and logistic regression models for predicting PIU, show how the depression level constitutes a risk factor for PIU: seven times higher for severe depression; more than five times higher for moderate depression; and more than two times for mild depression. (4) Conclusions: There is a clear association between depression and PIU, suggesting that a higher level of depression would act as a predictor of PIU. However, this finding is exploratory. Future studies should clarify the directionality of the relationship between both variables.

Investigation of In Vitro Toxicity of Newly Synthesized Mesoporous Silica Nanotubes with Different Pore Sizes in Human Liver Cancer Cells (HepG2)

Nanotechnology has gained importance in recent years with the use of nanomaterials smaller than human cells in many areas such as food, cosmetics, defense industry and pharmaceutical industry. It has begun to be widely used in the field of health in the diagnosis and treatment of many diseases, especially cancer. However, due to their size and content, these materials can be toxic and pose a risk to human health. In this study, the cytotoxic effects of mesoporous silicon dioxide (SiO2) nanoparticles with different pore sizes, synthesized using a new method and made from polyethylene glycol 6000 (PEG6000) and polyethylene glycol 35000 (PEG35000) were tested on HepG2 cells liver carcinoma cells. Additionally, the effects of mesoporous silica nanotubes on lipid peroxidation and reactive oxygen species (ROS) were also examined. It was found that the cytotoxicity of both types of mesoporous SiO2 nanoparticles increased with rising concentration. Cell viability decreased significantly as the nanoparticles dosage (100-10 μg/mL) increased. Both nanoparticles were not cytotoxic at concentrations up to 50 µg/mL, however, they became cytotoxic at higher concentrations (p

A scoping review of the impact of COVID-19 on dentistry: financial aspects

BackgroundThe technological advancements of the past few decades in various aspects that are directly or indirectly related to health, along with the emphasis on public health in societal development, have improved the quality of life.However, the occurrence of pandemics and crises underscores how various aspects of individual life can be impacted. The financial consequences resulting from the COVID-19 pandemic have particularly affected the field of dentistry and public oral health. This study aims to investigate the financial effects of the COVID-19 virus on dentistry through a scoping review.MethodsA comprehensive literature search was conducted across four databases (Medline through PubMed, Embase, Scopus, and Cochrane Central) using keywords such as COVID-19 and its equivalents, dentistry, oral health, dental education, dental services, dental clinics, financial impact, financial opportunities and economic impact. Articles addressing the financial impact of COVID-19 on dentistry and oral health were then screened and reviewed.ResultsOut of 1015 articles related to COVID-19 and dentistry, 84 were focused on the financial impact of COVID-19 on dentistry. The majority of these articles originated from the United States, Brazil, and Saudi Arabia, with a prevalence of cross-sectional and review articles. The review categorized the articles into two main themes: financial problems and proposed solutions. Moreover, the following themes were extracted: the effects of practice closure on dentists and staff, increased treatment costs and impacts on oral health, personal protective equipment and unforeseen costs, psychological effects of financial issues, and financial challenges within the dental education system.ConclusionsWhile many high-income countries seem able to mitigate COVID-19-induced financial problems, the economic effects on dentistry might persist despite the pandemic's end. These financial challenges have spurred new opportunities and infrastructure development but can pose significant risks to community oral health. This study aimed to highlight these problems and propose solutions, contributing to efforts to improve the oral health of communities globally. Further research is needed to understand long-term impacts.

Understanding Health Care Students' Perceptions, Beliefs, and Attitudes Toward AI-Powered Language Models: Cross-Sectional Study.

ChatGPT was not intended for use in health care, but it has potential benefits that depend on end-user understanding and acceptability, which is where health care students become crucial. There is still a limited amount of research in this area. The primary aim of our study was to assess the frequency of ChatGPT use, the perceived level of knowledge, the perceived risks associated with its use, and the ethical issues, as well as attitudes toward the use of ChatGPT in the context of education in the field of health. In addition, we aimed to examine whether there were differences across groups based on demographic variables. The second part of the study aimed to assess the association between the frequency of use, the level of perceived knowledge, the level of risk perception, and the level of perception of ethics as predictive factors for participants' attitudes toward the use of ChatGPT. A cross-sectional survey was conducted from May to June 2023 encompassing students of medicine, nursing, dentistry, nutrition, and laboratory science across the Americas. The study used descriptive analysis, chi-square tests, and ANOVA to assess statistical significance across different categories. The study used several ordinal logistic regression models to analyze the impact of predictive factors (frequency of use, perception of knowledge, perception of risk, and ethics perception scores) on attitude as the dependent variable. The models were adjusted for gender, institution type, major, and country. Stata was used to conduct all the analyses. Of 2661 health care students, 42.99% (n=1144) were unaware of ChatGPT. The median score of knowledge was "minimal" (median 2.00, IQR 1.00-3.00). Most respondents (median 2.61, IQR 2.11-3.11) regarded ChatGPT as neither ethical nor unethical. Most participants (median 3.89, IQR 3.44-4.34) "somewhat agreed" that ChatGPT (1) benefits health care settings, (2) provides trustworthy data, (3) is a helpful tool for clinical and educational medical information access, and (4) makes the work easier. In total, 70% (7/10) of people used it for homework. As the perceived knowledge of ChatGPT increased, there was a stronger tendency with regard to having a favorable attitude toward ChatGPT. Higher ethical consideration perception ratings increased the likelihood of considering ChatGPT as a source of trustworthy health care information (odds ratio [OR] 1.620, 95% CI 1.498-1.752), beneficial in medical issues (OR 1.495, 95% CI 1.452-1.539), and useful for medical literature (OR 1.494, 95% CI 1.426-1.564; P<.001 for all results). Over 40% of American health care students (1144/2661, 42.99%) were unaware of ChatGPT despite its extensive use in the health field. Our data revealed the positive attitudes toward ChatGPT and the desire to learn more about it. Medical educators must explore how chatbots may be included in undergraduate health care education programs.

Mental Health Literacy Level Of University Students Enrolled In Health Departments: A Descriptive Study in Turkey

Introduction: Good mental health literacy (MHL) enables an individual to access, understand, and use information in a way that promotes and maintains good mental health and facilitates early referral to mental health services. The literature reports that MHL levels among adolescents are gradually increasing, but still remain at low/moderate levels, and that this situation bears a negative impact on both individual and societal health. Aims: The Authors of this study aim to determine the level of MHL among university students engaged in the field of health, the factors that influence this level, and the differences between the various fields. Methods: The sample of this cross-sectional study consisted of 1,227 students enrolled in a university health department between 1 December 2022 and 20 January 2023. Data were collected online using a questionnaire designed by the researchers, and applying the MHL Scale (MHLS). We used descriptive statistics, one-sample t-test, one-way ANOVA test, multiple comparison tests (Tukey) and multiple linear regression in the statistical analysis. Results: The mean MHLS score of health faculty students was moderate (15.88, SD = 3.30). Female students, students aged &gt;20 years and medicine, dentistry or nursing students had higher MHLS scores than others (p &lt; .050). Conclusions: We observed that university students in the health sector did not have the desired or expected level of MHL. Improving MHL has the potential to facilitate early intervention, ensuring effective community mental health promotion and support; therefore, educational programs should be developed for this group.

Challenge in Social Management and Active Methodology in Medical Education

Objective: Investigate understanding the impact of the active Problem Based Learning (PBL) methodology on the knowledge consolidated during medical graduation and the challenge of social management. Theoretical Framework: Social management is a process that is taken to a specific community and is based on collective, continuous and open learning for the design and execution of projects that respond to the needs and problems of a specific focus. In this context, we involve the learning process as a dynamic process that suffers from interference from all of an individual's biopsychosocial components. Understanding that different teaching techniques generate different results in content retention and learning itself is essential for new methodologies and technologies to be developed in order to facilitate this process. In this sense, the problem-based method or PBL consists of a teaching model centered on the student and their knowledge and the teacher in the figure of a tutor, who guides the student on the learning journey, and is shown to be an innovative method, modifying relationships between learning agents and knowledge itself, especially in the academic environment. Method: The methodology adopted for this research comprises a bibliographical review of the literature. Data collection was carried out through articles published on the PubMed and SciELO platforms, totaling 13 articles that met the inclusion criteria. Results and Discussion: The results obtained revealed that PBL promotes a significant improvement in students' critical thinking capacity, and the implementation of PBL in teaching environments was associated with significant learning and the development of essential skills for academic development and professional practice. In general, the articles analyzed show that choosing PBL as a teaching method in different educational contexts not only improves academic performance, but also develops crucial skills for professional practice, preparing students to face complex challenges and improve their capabilities at the same time. throughout their careers. Originality/Value: This study contributes to the literature by addressing the use of PBL as a dynamic and effective teaching method, compared to traditional teaching and social management. The relevance and value of this research are based on the extent to which it addresses a learning model that can provide essential skills for training in the health field.

Expectations of Katowice residents regarding the program assumptions of the European city of science Katowice 2024 in the field of medical and health sciences - questionnaire survey results

IntroductionScientific literacy has been the subject of studies for several decades, but there is much less interest in the social perception of science, traceability of key areas of scientific activity and social expectations regarding science. Proper recognition of such issues can significantly contribute to a better understanding of the causes of the crisis of trust in science and help to find an effective and socially acceptable solution to mitigate it. Our study was aimed at identifying and systematizing the public needs and expectations towards medical and health sciences, based on the example of the population of Katowice.Materials and methodsThe study was carried out using a mixed, qualitative-quantitative methodology. Based on the conclusions of the in-depth interviews, a questionnaire was constructed to check the level of awareness of residents of Katowice obtaining the title of the European City of Science 2024 and the respondents’ opinion on the development of medical and health sciences. 400 inhabitants of the city and/or people associated with it through their work or education took part in the questionnaire survey.ResultsOnly 7.8% of respondents had in-depth knowledge about the European City of Science 2024 project, with further 28.8% declaring some level of general knowledge of the issue. Study participants associated medical and health sciences with health promotion and clinical specialties (43% and 33,5% respectively). In terms of further development of medical and health sciences in Katowice study participants prioritized mainly development of research in chronic and lifestyle-related diseases (51%) and the need of development of prevention and health promotion (46.3%) as well as clinical medicine (32.8%). The inhabitants of the city recognize the resources of the city and the region in the field of medical sciences and health sciences as large and with high development potential.ConclusionsThe events organized as part of the European City of Science 2024 should become a good opportunity to promote and disseminate knowledge about the achievements and development potential of the City and the Region in the field of medical and health sciences.

Development of a Global Physical Literacy (GloPL) Action Framework: Study protocol for a consensus process.

The holistic concept of physical literacy (PL) has gained growing attention in recent research, policy, and practice. Many important policy documents of the physical activity and educational fields (e.g., Global Action Plan on Physical Activity 2018-2030 by the World Health Organization, UNESCO's Quality Physical Education guidelines for policymakers) have specified PL. However, a clear framework for action is needed, as most initiatives across the world are fragmented, lack a prospective orientation, can benefit from conceptual clarification, and are not linked to effective translation into practice. Therefore, we aim to consensually develop a Global Physical Literacy (GloPL) Action Framework to define goals and principles (asking what is needed) as well as actions and ways (asking how these can be achieved) to move PL forward. We apply a three-stage group Delphi technique involving three representation groups: (a) geographical representatives to achieve global coverage of perspectives; (b) representatives of special thematic interest reflecting prominent gaps of current PL activities; and (c) representatives of societies from the broad field of physical activity and health to facilitate dissemination. The process will begin with an individual pre-Delphi exercise, in which experts generate initial ideas for the framework, followed by a four-eye document analysis to derive themes for the discussion. Subsequently, the experts will meet face-to-face in three online rounds to discuss and prioritize the themes. Interspersed formal voting with pre-defined agreement thresholds (via descriptive statistics) will inform the inclusion of themes within the final framework. A global consensus on goals, principles, actions, and ways for the development of PL has the potential to provide a largely accepted roadmap for future activities in research, policy, and practice. The co-production approach will help disseminate the GloPL Action Framework and benefit work in relevant application fields of physical activity and health worldwide.

A systematic review on the use of phytotherapy in managing clinical depression

Introduction: The use of medicinal plants in the management of depression, also known as phytotherapy or herbal medicine for depression, is an area of growing interest in the field of mental health and complementary medicine. Methods: This study used a systematic assessment of pertinent literature to assess the effectiveness of medicinal herbs in treating mild to severe depression. A comprehensive literature search was conducted to identify randomized controlled trials (RCTs) that reported data on the intervention, control group, adverse events, outcome measurements, and main findings. A summary and analysis were done on the included research data. Results: We included 23 RCTs investigating the efficacy of herbal medicines, including Crocus sativus, Lavandula angustifolia, Melissa officinalis, and Echium amoenum, in treating depression. In general, saffron showed encouraging outcomes when used to treat mild to severe depression. With no discernible variations in the reported adverse effects, it proved to be equally efficacious as well-known antidepressants like imipramine and fluoxetine. However, it is noteworthy that not all trials yielded favorable results. Conclusion: More investigation is required to fully understand the mechanisms of action, ideal dosage schedules, long-term effects, and relative efficacy of medicinal plants in depressive treatment.

Amphiphilic Janus nanoparticles with controlled composition and wettability for pickering emulsion with controllable movement and release

Pickering emulsions represent an important class of functional materials with great potentials in field of sustainability and health, such as controlled drug release or catalysis. However, the limited tunability of the amphiphilicity and implementation of multiple components into Pickering emulsion are still challenges for reliable dynamic control. Here, a strategy to obtain a triphasic amphiphilic PS/Fe3O4@SiO2 Janus nanoparticles (JNPs) by cladding Fe3O4 NPs inside biphasic PS@SiO2 JNPs was proposed and validated. The sizes of the triphasic JNPs is in the range of 80–150 nm and water contact angle (θW) varies from 58.9° to 131.4°, indicating the wettability could be controlled at will. The formed JNPs are assembled at the oil-water interface to stabilize water-in-oil (W/O) and oil-in-water (O/W) emulsion droplets. The stabilized emulsion droplets exhibit excellent thermodynamic stability which is evidenced by the droplet viability of 50 %-80 % after 6 months or excellent salt and temperature-resistance. Moreover, the movement and demulsification are made possible with magnetic actuation of JNPs. Compared to without magnetism, the release of curcumin dissolved in water within W/O droplet was realized 70 % after 12 days, showing a promising application in controlled active material release. Taking advantage of controllable synthesis and the functionality, this proposed approach could be expanded for preparation of colloidal materials with complex chemical and incorporate additional functionality, suggesting opportunities for further applications in drug delivery, oil recovery fields, and other fields related Pickering emulsion.

Omega-3 Polyunsaturated Fatty Acids in Depression.

Omega-3 polyunsaturated fatty acids have received considerable attention in the field of mental health, in particular regarding the treatment of depression. This review presents an overview of current research on the role of omega-3 fatty acids in the prevention and treatment of depressive disorders. The existing body of evidence demonstrates that omega-3 fatty acids, in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have antidepressant effects that can be attributed to their modulation of neuroinflammation, neurotransmitter function, and neuroplasticity. Nevertheless, clinical trials of omega-3 supplementation have yielded inconsistent results. Some studies have demonstrated significant reductions in depressive symptoms following omega-3 treatment, whereas others have shown minimal to no beneficial impact. A range of factors, encompassing dosage, the ratio of EPA to DHA, and baseline nutritional status, have been identified as having a potential impact on the noted results. Furthermore, it has been suggested that omega-3 fatty acids may act as an adjunctive treatment for those undergoing antidepressant treatment. Notwithstanding these encouraging findings, discrepancies in study designs and variability in individual responses underscore the necessity of further research in order to establish uniform, standardized guidelines for the use of omega-3 fatty acids in the management of depressive disorders.

Five years on: analysis of university lecturers’ experiences of the French government’s health promotion education program

BackgroundThe National Health Promotion Intervention Program by Student (HPIPS) is a French government educational program introduced in 2018, aiming at developing all health students’ health promotion knowledge and abilities, as well as implementing health promotion interventions for specific subpopulations in the general public. Its pedagogical framework was elaborated in 2018 and then evaluated by the French Council for Public Health in 2022, highlighting certain difficulties for the program to be homogeneously implemented in France. The aim of this study was to explore and describe the experiences and feedback of university lecturers in charge of this HPIPS training.MethodsSemi-structured interviews were conducted with HPIPS lecturers from various health fields and from French universities, and a qualitative content analysis was carried out.ResultsFourteen interviews were conducted during the autumn of 2022 with HPIPS program university lecturers including five doctors, three dentists, two nurses, two pharmacists, one midwife, and one physiotherapist from eight different towns belonging to six regions. Depending on the professional background, the component, and the local resources available, the teaching experience varied from one lecturer to another. A number of difficulties arose in setting up this educational program and complying with the latter legislation. The work overload was considerable, and the lecturers’ heavy commitments some lecturers to be discouraged, especially since some lecturers were not trained in health promotion abilities. Although interprofessionality was a strength of this HPIPS, it was also its main challenge. Pedagogical innovations were developed, notably through the use of digital technology; cross-disciplinary collaboration was established; and lecturers–students specific boundaries have emerged thanks to this health promotion project.ConclusionsIn France, setting up the HPIPS rapidly was experienced as a real pedagogical challenge for the interviewed university lecturers. While most of them noted the positive and beneficial contributions made by the introduction of prevention and health promotion intervention skills for health students, they also shared recommendations in order to match the ambitions and increase the HPIPS impact on the development of a culture of prevention and health promotion among health students.

Artificial intelligence applications in the diagnosis and treatment of bacterial infections.

The diagnosis and treatment of bacterial infections in the medical and public health field in the 21st century remain significantly challenging. Artificial Intelligence (AI) has emerged as a powerful new tool in diagnosing and treating bacterial infections. AI is rapidly revolutionizing epidemiological studies of infectious diseases, providing effective early warning, prevention, and control of outbreaks. Machine learning models provide a highly flexible way to simulate and predict the complex mechanisms of pathogen-host interactions, which is crucial for a comprehensive understanding of the nature of diseases. Machine learning-based pathogen identification technology and antimicrobial drug susceptibility testing break through the limitations of traditional methods, significantly shorten the time from sample collection to the determination of result, and greatly improve the speed and accuracy of laboratory testing. In addition, AI technology application in treating bacterial infections, particularly in the research and development of drugs and vaccines, and the application of innovative therapies such as bacteriophage, provides new strategies for improving therapy and curbing bacterial resistance. Although AI has a broad application prospect in diagnosing and treating bacterial infections, significant challenges remain in data quality and quantity, model interpretability, clinical integration, and patient privacy protection. To overcome these challenges and, realize widespread application in clinical practice, interdisciplinary cooperation, technology innovation, and policy support are essential components of the joint efforts required. In summary, with continuous advancements and in-depth application of AI technology, AI will enable doctors to more effectivelyaddress the challenge of bacterial infection, promoting the development of medical practice toward precision, efficiency, and personalization; optimizing the best nursing and treatment plans for patients; and providing strong support for public health safety.