Abstract Issue Improving uptake of Cancer Screening programs (CS) remains a public health priority in France, as stated in the latest national cancer control strategy. The French Society for Public Health designed in 2020 a project to document Interventions Promoting CS Participation (IPCSP) for vulnerable groups, for both breast and cervical cancers. This project provides experiential and practical evidence built up from IPCSP and offers relevant insights for the new strategy. Methods The project aims at capitalizing, i.e. collecting, documenting and circulating, experiential knowledge from practitioners who implement IPCSP locally (health professionals, social workers, grassroots organizations, etc.). The project consists in 3 main steps: 1/identify promising IPCSP through a nationwide call for applications; 2/ document the key mechanisms impacting how IPCSP unfold (context, partnerships, barriers and levers, ethics), 3/ publish a summary for each IPCSP, available online. The goal is to build up original knowledge from field actions, documenting how IPCSP tackle several factors that can hinder uptake, in various contexts. Results 20 IPCSP were selected. IPCSP targets included: women of low-income neighborhoods, allophone women, inhabitants of healthcare deserts, handicapped persons, etc. Most IPCSP (16 out of 20) featured reaching out strategies, such as: peer education, on-site screenings, etc. All promoted informed choice. A cross-case analysis of IPCSP highlighted key, recurring implementation levers. One is co-constructing IPCSP throughout within local, multi-professional, long-standing partnerships, in which partners bring complementary skills: medical expertise, proximity with target populations, project management skills, community engagement skills, etc. Lessons 20 detailed summaries will offer concrete data on how to put insights to enhance CS uptake into action. Other stakeholders and policymakers alike can benefit from experiential knowledge built up from IPCSP. Key messages Documenting interventions promoting uptake of breast and cervical cancer screening programs and detailing how they work is crucial to building knowledge and to helping enhance participation for all. Partnerships can provide effective, population-specific and context-specific levers to promote uptake of cancer screening programs in France. Co-constructing the intervention throughout is key.
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