Computational fluid dynamics (CFD) simulations for obtaining three-dimensional hypersonic vehicle aerodynamic characteristics are resource-intensive. Deep learning offers a promising alternative for predicting aerodynamic wall quantities but typically requires a large dataset, which conflicts with the intention to reduce CFD costs. To address this, we propose a novel prediction model leveraging variable fidelity data to alleviate computational demands. The model utilizes an encoder-decoder architecture with ConvNeXt blocks as operators, processing variable fidelity data as inputs and outputs. We also developed a U-Net with residual blocks (ResUNet) for performance comparison. Transformation and topology patching techniques were applied to tackle the challenges posed by large grid volumes and complex topologies in three-dimensional vehicles. Results demonstrate that the ConvNeXt Encoder-Decoder predicts peak regions more accurately than ResUNet and aligns closely with CFD in low-value areas. The ConvNeXt Encoder-Decoder maintains maximum heat flux errors below 1 % and viscous drag errors below 3.81 % across varying angles of attack. It exhibits superior fitting performance with minimal deviation from CFD compared to ResUNet. Prediction accuracy decreases under multiple inflow changes compared to the angle of attack variations alone. Heat flux predictions show high consistency with CFD, with relative errors below 6.38 %, whereas friction predictions exhibit higher errors with 10.28 % maximum error and 0.28 % minimum error. The model accurately predicts friction variation trends in peak regions at the blunt edge's central plane but performs poorly in low-value areas. In summary, the ConvNeXt Encoder-Decoder accurately predicts the wall quantities under varying multiple inflow conditions.