Bisphenol A known as BPA is a chemical compound which used to strengthen various plastic products. BPA is well known endocrine disruptor and continuous adulteration of BPA through various resources will result in type-II diabetes in human being. Therefore, it is essential and important to measure endocrine disruptors known as hormone disruptors, which increase the risk of diabetes, and cancer in human being. The chemical capability of BPA also alters, affects brain chemistry, behavior, reproductive systems, and prostate glands in fetuses, infants, and in children. About 90% of us accumulate BPA levels through food containers, baby feeding bottles, thermal printing papers, and from the water bottles. In 2010 the toxicity levels revealed the importance of removing of BPA from the plastic products such as baby feeding bottles, baby formula bottles, pacifiers, canned foods, and in the inner lining of beverages. Therefore, it is important to detect and determine the toxicity levels of BPA in the commercial products. Herein, we report the electrochemical detection of BP compounds based on modified/pretreated electrodes at lab scale. We have detected and determined the BP concentrations in the physiological pH conditions using these electrodes. Further the sensitivity, selectivity, and linear range of these electrodes falls within the range to fabricate real time electrodes to sense BP contamination in the real-time applications. Acknowledgment: The research work presented herein is financially supported by USDA-NIFA