The recently proposed theories with TeV-scale quantum gravity remove the usual ultraviolet desert between $\sim 10^{3} - 10^{19}$ GeV where effective field theory ideas apply. Consequently, the success of the desert in explaining approximate symmetries is lost, and theories of flavor, neutrino masses, proton longevity or supersymmetry breaking, lose their usual habitat. In this paper we show that these ideas can find a new home in an infrared desert: the large space in the extra dimensions. The main idea is that symmetries are primordially exact on our brane, but are broken at O(1) on distant branes. This breaking is communicated to us in a distance-suppressed way by bulk messengers. We illustrate these ideas in a number of settings: 1) We construct theories for the fermion mass hierarchy which avoid large FCNC's. 2) We re-iterate that proton stability can arise if baryon number is gauged in the bulk. 3) We study experimental constraints on light gauge fields and scalars in the bulk. 4) We remark that the same ideas can be used to explain small neutrino masses, and hierarchical supersymmetry breaking. 5) We construct a theory with bulk technicolor, avoiding the difficulties with extended technicolor. There are also interesting experimental signals of these ideas: 1) Attractive or repulsive, isotope dependent sub-millimeter forces $\sim 10^6$ times gravitational strength, from the exchange of light bulk particles. 2) Novel Higgs decays to light generation fermions plus bulk scalars. 3) Collider production of bulk vector and scalar fields, leading to large $\gamma$ or jet+ missing energy signals.