There is a paucity of research about personality pathology among female offenders. This study aims to address this gap in the forensic psychology empirical base by examining the relationship between female psychopathy, as measured by the Psychopathy Checklist–Revised, and personality disorders, as measured by the Millon Clinical Multiaxial Inventory-III in a South African forensic context. Participants included 108 purposively sampled female offenders incarcerated in South Africa. The Kruskal–Wallis H test and Mann–Whitney U test revealed a number of significant differences in levels of personality pathology between groups. Importantly, the results support international findings that significantly higher rates of Cluster B personality pathology are found among psychopathic offenders compared to non-psychopathic offenders.