Emotional intelligence is a skill involving understanding, perceiving, managing, and utilizing information. Nurses with high emotional intelligence may have high life satisfaction which can enhance their productivity in the workplace by effectively managing emotions. Objective: To explore the role of emotional intelligence in life satisfaction among hospital nurses in Pakistan. Methods: A correlational study was conducted involving purposive sampling of 511 registered female nurses, aged 20 to 45 in Karachi and Hyderabad, Pakistan. Life satisfaction was assessed using a subset of the ICP-Subjective Wellbeing Scale while for Emotional Intelligence, Trait Emotional Intelligence Questionnaire-Short Form (TEIQue-SF) was used. Ethical considerations were stringently adhered to throughout the study, maintaining participant confidentiality and ensuring adherence to research norms. Results: The results revealed a significant predictive relationship between EI and life satisfaction in female hospital nurses [r = .199; R2=.040, F (510) = 20.994, p<.000]. Conclusions: Globally, Nurses are considered vital to healthcare system, including in Pakistan where mental health issues among them are notable. The study concluded that emotional intelligence predicts higher life satisfaction among hospital nurses.