Tongue Tip Research Articles

Alpha Suppression Is Associated with the Tip-of-the-Tongue (TOT) State Whereas Alpha Expression Is Associated with Knowing That One Does Not Know.

The tip-of-the-tongue (TOT) state is a spontaneously occurring metacognitive state that indicates that the answer to a query is almost, but not quite, at hand, i.e., that resolution is imminent. Since the time of William James, a distinctive feeling of nagging frustration has been observed to be associated with TOT states. On a more positive note, TOT states are also associated with intense goal-directed curiosity and with a strong desire to know that translates into successful mental action. The present study showed that prior to the presentation of resolving feedback to verbal queries-if the individual was in a TOT state-alpha suppression was in evidence in the EEG. This alpha suppression appears to be a marker of a spontaneously occurring, conscious, and highly motivating goal-directed internal metacognitive state. At the same time, alpha expression in the same time period was associated with the feeling of not knowing, indicating a more discursive state. Both alpha and alpha suppression were observed broadly across centro-parietal scalp electrodes and disappeared immediately upon presentation of the resolving feedback. Analyses indicated that the occurrence of alpha suppression was associated with participants' verbal affirmations of being in a TOT state, which is also related to subsequent expression of a late positivity when feedback is provided, and to enhanced memory.

Traumatic Fibroma of Tongue

Traumatic or irritational fibroma is a common benign exophytic and reactive oral lesion that develops secondary to injury. Fibroma is a result of a chronic repair process that includes granulation tissue and scar formation resulting in a fibrous submucosal mass. The most common sites of traumatic fibroma are the tongue, buccal mucosa and lower labial mucosa. This article presents the case of a 35-year-old female patient with 2 months-long proliferation on the tip of the tongue. Here, electrocautery was used for the complete excision of the lesion. The main advantages of using it is effective hemostasis that can be achieved in a short span, is less invasive, and better postoperative phase

Tongue papillae density and fat taster status- a cardinal role on sweet and bitter taste perception among Indian population

Obesity is a complex nutritional disorder that may be influenced by calorie intake and eating behaviours. Aside from many studies, the influence of papillae count on obesity is still debated. Despite the multiple variables connected to weight gain and altered taste perception, determining the association between papillae count and taste sensitivity to fat, sweet and bitter tastes, in particular, has recently become a focus of attention. This study aimed to rule out the relationship between the number of papillae on different areas of the tongue and taste sensitivity in people (n = 150) among the various groups depending on their body mass index (BMI) and fat taste sensitivity. The general labelled magnitude scale (gLMS) was used for the taste sensitivity analysis, and participants were asked to rate the intensity of each concentration of the different tastants. Using a digital camera to obtain a picture of the tongue, the density of the papillae on the tongue was counted manually by three different operators. The study reveals that the total papillae density and BMI had a direct negative correlation (r = -0.43), with papillae density (PD) decreasing as BMI increased. Concurrently, persons with higher BMIs had lower papillae distributions (32.38 ± 1.85 PD/cm2) and significantly lower perceptions of the intensity of fat taste. Further examining papillae density in the anterior front part of the tongue, the front-right section, showed significantly higher papillae distribution (74.04 ± 2.11 PD/cm2) than the front-left section. When considering the sensitivity in the tip of the tongue, middle tongue, and whole mouth, high-sensitivity individuals for fat are more sensitive to both sweet and bitter tastes. Overall, the results of this study demonstrated a strong relationship between taste sensitivity in the Indian population, BMI, and tongue papillae density in various regions of the tongue.

Effects of different surgical treatments on children with ankyloglossia: protocol for a systematic review and meta-analysis

IntroductionAnkyloglossia is a situation where the tongue tip cannot go beyond the mandibular incisor because the frenulum linguae is short. It could affect children’s health by interfering with their ability...

“Tip of the Tongue”: Experimental Reconstruction of Handaxes at the Baise Basin (South China) and Implications for Lithic Standardization

ABSTRACT Geometric morphometric studies in the Baise Basin in South China have documented unique tongue-like tip morphologies in handaxes sampled from the fourth terrace of the Youjiang River Valley. With this study, we report on a new handaxe assemblage found at the Natang site and present data that further document the prevalence of these rounded tip morphologies in the region. We use experimental replications to recreate the unique morphology of the handaxes, and demonstrate that a specific tip rounding strategy was employed by hominins as an economic and effective way to produce wider, more rounded and thinner distal tips. We suggest that these tongue-like tips indicate a predetermined design, and consequently, reflect a level of shape standardization that is heightened in functional tool portions. Moreover, this study provides further documentation of the regionally unique tool-making preferences that Pleistocene hominins employed when flexibly adapting to local environmental conditions and resource availabilities.

Tongue diagnosis based on hue-saturation value color space: controlled study of tongue appearance in patients treated with percutaneous coronary intervention for coronary heart disease

ObjectiveTo analyze the characteristics of tongue imaging color parameters in patients treated with percutaneous coronary intervention (PCI) and non-PCI for coronary atherosclerotic heart disease (CHD), and to observe the effects of PCI on the tongue images of patients as a basis for the clinical diagnosis and treatment of patients with CHD. MethodsThis study used a retrospective cross-sectional survey to analyze tongue photographs and medical history information from 204 patients with CHD between November 2018 and July 2020. Tongue images of each subject were obtained using the Z-BOX Series traditional Chinese medicine (TCM) intelligent diagnosis instruments, the SMX System 2.0 was used to transform the image data into parameters in the HSV color space, and finally the parameters of the tongue image between patients in the PCI-treated and non-PCI-treated groups for CHD were analyzed. ResultsAmong the 204 patients, 112 were in the non-PCI treatment group (38 men and 74 women; average age of (68.76 ± 9.49) years), 92 were in the PCI treatment group (66 men and 26 women; average age of (66.02 ± 10.22) years). In the PCI treatment group, the H values of the middle and tip of the tongue and the overall coating of the tongue were lower (P < 0.05), while the V values of the middle, tip, both sides of the tongue, the whole tongue and the overall coating of the tongue were higher (P < 0.05). ConclusionThe color parameters of the tongue image could reflect the physical state of patients treated with PCI, which may provide a basis for the clinical diagnosis and treatment of patients with CHD.

Molecular Screening, Docking and DFT Study of Phytochemicals from Sesbania grandiflora against HER 2 Protein of Oral Cancer

The most frequent type of head and neck cancer is oral cancer (mouth cancer). It usually affects adults over the age of 60. Oral cancer affects your lips, the tip of your tongue, and the roof and floor of your mouth. It also affects the oropharynx, which includes the last section of your tongue and the roof of your mouth, as well as your tonsils and the sides and back of your throat. It is getting a global threat. Excess consumption of Tobacco and alcohol are the key factors of Oral cancer. Sesbania grandiflora is a medicinal plant found in most of the regions of Asia including India. It is full of medicinal properties. Here, in this investigation 33 reported phyto compounds are taken from Sesbania grandiflora and undergone various in silico study. Here, the highly expressed HER 2 protein in oral cancer is targeted. The compounds which pass in computation investigation were docked against the HER 2 protein of Oral cancer. The Sativan was found to be the highest binding affinity scoring molecule among phyto selected from this plant and expected to stop the over expression of HER 2 protein and future drug candidate .

Functional Role of Temporal Patterning of Articulation in Speech Production: A Novel Perspective Toward Global Timing-Based Motor Speech Assessment and Rehabilitation.

This study aimed to (a) relate temporal patterning of articulation to functional speech outcomes in neurologically healthy and impaired speakers, (b) identify changes in temporal patterning of articulation in neurologically impaired speakers, and (c) evaluate how these changes can be modulated by speaking rate manipulation. Thirteen individuals with amyotrophic lateral sclerosis (ALS) and 10 neurologically healthy controls read a sentence 3 times, first at their habitual rate and then at a voluntarily slowed rate. Temporal patterning of articulation was assessed by 24 features characterizing the modulation patterns within (intra) and between (inter) four articulators (tongue tip, tongue body, lower lip, and jaw) at three linguistically relevant, hierarchically nested timescales corresponding to stress, syllable, and onset-rime/phoneme. For Aim 1, the features for the habitual rate condition were factorized and correlated with two functional speech outcomes-speech intelligibility and intelligible speaking rate. For Aims 2 and 3, the features were compared between groups and rate conditions, respectiely. For Aim 1, the modulation features combined were moderately to strongly correlated with intelligibility (R 2 = .51-.53) and intelligible speaking rate (R 2 = .63-.73). For Aim 2, intra-articulator modulation was impaired in ALS, manifested by moderate-to-large decreases in modulation depth at all timescales and cross-timescale phase synchronization. Interarticulator modulation was relatively unaffected. For Aim 3, voluntary rate reduction improved several intra-articulator modulation features identified as being susceptible to the disease effect in individuals with ALS. Disrupted temporal patterning of articulation, presumably reflecting impaired articulatory entrainment to linguistic rhythms, may contribute to functional speech declines in ALS. These impairments tend to be improved through voluntary rate reduction, possibly by reshaping the temporal template of motor plans to better accommodate the disease-related neuromechanical constraints in the articulatory system. These findings shed light on a novel perspective toward global timing-based motor speech assessment and rehabilitation.

Pediatric bronchogenic cysts in the head and neck region: A study of 10 surgical cases and a review of the literature.

To explore the clinical characteristics and surgical treatment of children with bronchogenic cysts (BCs) in the head and neck region. A retrospective study of 10 pediatric patients with BCs in the head and neck region treated in Shanghai Children's Hospital during 2011 to 2022 was performed. Based on their pathological diagnosis, 10 patients with BCs in the head and neck were identified. The most common location was the neck (8 patients, 80%; 2 midline neck, 6 lateral neck), followed by the ventral tip of tongue (1 patient), and the posterior pharyngeal wall (1 patient). Misdiagnosed as lymphangioma in 5 cases, cyst in 3 cases, thyroglossal duct cyst (TGDC) in 2 cases and congenital pyriform sinus fistula (CPSF) in 1 case preoperative. The median follow-up period after surgery was 4.68 (range, 0.67-9.25) years. All 10 patients underwent complete resection without recurrence or other complications. Although extremely rare, BCs should be considered in the differential diagnosis of midline and lateral neck masses or intraoral cysts in children. Surgical excision is recommended in BCs, and the diagnosis is definitively confirmed by histopathology.

Unexpected Candidal Hyphae in Oral Mucosa Lesions-A Clinico-Pathological Study.

Background: Oral mucosal biopsies might harbor candidal hyphae (CH) in the absence of any clinical signs or symptoms. Aim: To assess oral mucosa biopsies for the frequency of unexpected CH and characterize their clinico-pathological features. Materials and Methods: All biopsy reports (2004–2019) were searched using CH/candida/candidiasis as key words. Cases with clinical diagnosis of oral candidiasis (OC) were excluded. Demographic data, health status, smoking habits, clinical features and diagnoses were collected. Statistical analysis included the chi-square test; significance was set at p < 0.05. Results: Of all the biopsies, 100 (1.05%) reported microscopical evidence of CH without typical clinical signs/symptoms of OC. Fifteen cases were from healthy, non-smoking patients. CH was common on buccal mucosa (38%) and lateral tongue (23%). The tip of tongue (OR = 54.5, 95% CI 9.02–329.4, p < 0.001) and lateral tongue (OR = 3.83, 95% CI 2.4–6.09, p < 0.001) were more likely to harbor CH-positive lesions. CH-positive lesions were diagnosed as epithelial hyperplasia (55%) and exophytic reactive lesions (30%). No correlation was found between CH and the grade of epithelial dysplasia. Conclusions: Microscopic evidence of CH embedded into oral epithelium without typical signs/symptoms of OC is rare, especially in healthy, non-smokers. Since CH was occasionally found in oral sites prone to local trauma and in association with reactive lesions, in absence of host co-morbidities, the contribution of local mechanical forces to CH embedment cannot be ruled out.

Reconsidering lateral vocalisation: Evidence from perception and production of Australian English /l/.

Lateral vocalisation is assumed to arise from changes in coronal articulation but is typically characterised perceptually without linking the vocalised percept to a coronal articulation. Therefore, we examined how listeners' perception of coda /l/ as vocalised relates to coronal closure. Perceptual stimuli were acquired by recording laterals produced by six speakers of Australian English using electromagnetic articulography (EMA). Tongue tip closure was monitored for each lateral in the EMA data. Increased incidence of incomplete coronal closure was found in coda /l/ relative to onset /l/. Having verified that the dataset included /l/ tokens produced with incomplete coronal closure-a primary articulatory cue of vocalised /l/-we conducted a perception study in which four highly experienced auditors rated each coda /l/ token from vocalised (3) to non-vocalised (0). An ordinal mixed model showed that increased tongue tip (TT) aperture and delay correlated with vocalised percept, but auditors ratings were characterised by a lack of inter-rater reliability. While the correlation between increased TT aperture, delay, and vocalised percept shows that there is some reliability in auditory classification, variation between auditors suggests that listeners may be sensitive to different sets of cues associated with lateral vocalisation that are not yet entirely understood.

Tuberculosis of the tongue

Introduction: Tuberculosis mostly affects the lungs, but may also affect the central nervous system, lymphatic system, circulatory system, genitourinary system, bones, joints, and skin. Extrapulmonary involvement in tuberculosis is rare, accounting for just 10 to 15% of cases. The lymph nodes are the second most common site of tuberculosis infection. Oral tuberculosis has long been thought to be an unusual phenomenon. Oral manifestations are thought to occur in just 0.05 to 5% of all tuberculosis cases. Surface ulcers, patches, papillomatous lesions, and indurated soft tissue lesions are the most common oral manifestations. Case Presentation: A 69-year-old man presented to the Department of Ear, Nose, Throat at MGM Hospital in Aurangabad, India, with a painful ulcer and tiny nodules on the tongue’s tip and lateral surface. The ulcer appeared 3–4 weeks ago without any obvious trigger with a prickling feeling and increased soreness over the area., Onintraoral inspection multiple small nodules is measuring about 0.1 cm and multiple circular ulcer measuring about 0.2 x 0.1 cm in diameter at the tip and lateral border of the tongue. A granulomatous center and a whitish, well-defined border with mild elevation characterized the ulcer. Conclusion: Despite the rarity of tuberculosis evidence in the oral cavity, oral tuberculosis should be included in the differential diagnosis of chronic oral lesions. To prevent ineffective oral therapy, accurate diagnosis is crucial for successful care by concentrating on the pathological source.

Porcine reproductive and respiratory syndrome virus RNA detection in tongue tips from dead animals.

The control of porcine reproductive and respiratory syndrome virus (PRRSV) hinges on monitoring and surveillance. The objective of this study was to assess PRRSV RNA detection by RT-PCR in tongue tips from dead suckling piglets compared to serum samples, processing fluids, and family oral fluids. Tongue tips and serum samples were collected from three PRRSV-positive breeding herd farms (farms A, B, and C) of three different age groups: newborns (<24 h), processing (2 to 7 days of age), and weaning (18 to 22 days of age). Additionally, processing fluids and family oral fluids were collected from 2–7 days of age and weaning age, respectively. In farms A and B, PRRSV RNA was detected in tongue tips from all age groups (100 and 95%, respectively). In addition, PRRSV RNA was detected in pooled serum samples (42 and 27%), processing fluids (100 and 50%), and family oral fluids (11 and 22%). Interestingly, the average Ct value from tongue tips was numerically lower than the average Ct value from serum samples in the newborn age. In farm C, PRRSV RNA was only detected in serum samples (60%) and family oral fluids (43%), both from the weaning age. Further, no PRRSV RNA was detected in tongue tips when pooled serum samples from the same age group tested PRRSV RNA-negative. Taken together, these results demonstrate the potential value of tongue tips for PRRSV monitoring and surveillance.

Developmental Changes in Coarticulation Degree Relate to Differences in Articulatory Patterns: An Empirically Grounded Modeling Approach.

Coarticulatory effects in speech vary across development, but the sources of this variation remain unclear. This study investigated whether developmental differences in intrasyllabic coarticulation degree could be explained by differences in children's articulatory patterns compared to adults. To address this question, we first compared the tongue configurations of 3- to 7-year-old German children to those of adults. The observed developmental differences were then examined through simulations with Task Dynamics Application, a Task Dynamics simulation system, to establish which articulatory modifications could best reproduce the empirical results. To generate syllables simulating the lack of tongue gesture differentiation, we tested three simulation scenarios. We found that younger speakers use less differentiated articulatory patterns to achieve alveolar constrictions than adults. The simulations corresponding to undifferentiated control of tongue tip and tongue body resulted in (a) tongue shapes similar to those observed in natural speech and (b) higher degrees of intrasyllabic coarticulation in children when compared to adults. Results provide evidence that differences in articulatory patterns contribute to developmental differences in coarticulation degree. This study further shows that empirically informed modeling can advance our understanding of changes in coarticulatory patterns across age.

Congenital smooth muscle hamartoma of the tongue in a neonate — a case report

BackgroundHamartoma is a benign, tumor-like proliferation of mature tissue that is natural to the organ from which it developed. Oral hamartomas are rare and can occur as an isolated finding or as a part of a syndrome.Case presentationWe report a 4-day-old male neonate who was postnatally noted to have a large 3.5 × 3.5 cm lobulated mass over the tip of the tongue. The mass was causing protrusion of the tongue and feeding difficulties following which surgical excision was planned. The postoperative recovery was uneventful.ConclusionAlthough rare, lingual hamartomas should be considered in the differential diagnosis algorithm for congenital tongue lesions. The definitive diagnosis is histopathological with complete resection of the tumor resulting in a favorable prognosis.

A-200 “It’s on the Tip of My Tongue!” – Base Rates and Neuroanatomical Correlates of Confrontation Naming Deficits in Patients with Multiple Sclerosis

Abstract Objective: Word-finding difficulty is a commonly reported complaint in patients with multiple sclerosis (pwMS), though it is often under evaluated in clinical care. This study sought to identify base rates of confrontation naming impairments relative to other language tasks and examine its neuroanatomical correlates in pwMS. Method: Of 372 pwMS referred for neuropsychological assessment, 185 (MAge=48.8±11.23; MEd=14.5±2.4; 83% White; 73% women) met inclusion criteria for the final sample (i.e., estimated premorbid IQ ≥70, English-speaking, valid data on performance validity indices). Norm-based T scores for the following tests were of interest: Boston Naming Test (BNT); Controlled Oral Word Association Test (COWAT); and Animal Fluency (AF). A subset of 50 patients underwent recent quantitative MRI variables for whole brain fraction (WBF) and white matter lesion burden (T2LV). Results: PwMS showed greater impairment (≤1.5 SD) on the BNT (27.6%) as compared to AF (18.4%; p=.002), but not COWAT (24.3%; p=.304) based on binomial tests. Controlling for age and sex, significant partial correlations (ps&amp;lt;.05) were identified between BNT and both WBF (r=.32) and T2LV (r=-.30) and between AF and T2LV (r = -.30). COWAT did not correlate significantly with WBF (r=.08) or T2LV (r=-.09). Conclusions: Confrontation naming is relatively frequently impaired in pwMS, and correlates with both cerebral volume and lesion burden. Semantic fluency correlated only with lesion burden, and phonemic fluency did not correlate with neuroimaging. Future research should continue to investigate the clinical presentation and neuroanatomical underpinnings of language dysfunction, particularly naming/word-finding difficulties, in pwMS.

RAPID TEST FOR SYPHILIS: IS IT RELIABLE?

Syphilis is a sexually transmitted infection caused by a bacterium (<i>Treponema pallidum</i>) that may present oral manifestations. A 26-year-old male patient presented with a 2-month history of a painful ulcer on the tongue. Medical history revealed low levels of hemoglobin and hematocrit. Intraoral examination showed an ulcer with well-defined borders on the tip of the tongue, measuring 1 cm in diameter. Moreover, erosive lesions with typical characteristics of benign migratory glossitis were seen in the tongue dorsum. The hypotheses for the ulcerated lesion were primary syphilis or ulceration related to anemia. Rapid tests for human immunodeficiency virus and syphilis were negative. A teleconsultation was required, and the oral medicine teleconsultant recommended Venereal Disease Research Laboratory and fluorescent treponemal antibody absorption exams, which confirmed the diagnosis of primary syphilis. The treatment included penicillin G benzathine (2,400,000 UI once a week for 3 weeks). Cases showing features suggesting syphilis require serological tests when rapid tests are negative.

Articulatory Underpinnings of Reduced Acoustic-Phonetic Contrasts in Individuals With Amyotrophic Lateral Sclerosis.

The aim of this study is to identify the articulatory underpinnings of the acoustic-phonetic correlates of functional speech decline in individuals with amyotrophic lateral sclerosis (ALS). Thirteen individuals with varying severities of speech impairment secondary to ALS and 10 neurologically healthy controls speakers read 12 minimal word pairs, targeting the contrasts in the height, advancement, and length of vowels; the manner and place of articulation for consonants and consonant cluster; and liquid and glide approximants, 5 times. Sixteen acoustic features were extracted to characterize the phonetic contrasts of these minimal word pairs. These acoustic features were correlated with a functional speech index-intelligible speaking rate-using penalized regression, based on which the contributive features were identified as the acoustic-phonetic correlates of the functional speech outcome. Articulatory contrasts of the minimal word pairs were characterized by a set of dissimilarity indices derived by the dynamic time warping algorithm, which measured the differences in the displacement and velocity trajectories of tongue tip, tongue dorsum, lower lip, and jaw between the minimal word pairs. The contributive articulatory features to the acoustic-phonetic correlates were identified by penalized regression. A variety of acoustic-phonetic features were identified as contributing to the functional speech outcome, of which the contrasts in vowel height and advancement, [r]-[l], [r]-[w], and initial cluster-singleton were the most affected in individuals with ALS. Differential articulatory underpinnings were identified for these acoustic-phonetic features. Impairments of these articulatory underpinnings, especially of tongue tip and tongue dorsum velocities and tongue tip displacement, were associated with reduced acoustic-phonetic contrasts of the minimal word pairs, in a context-specific manner. The findings established explanatory relationships between articulatory impairment and the acoustic-phonetic profile of functional speech decline in ALS, providing useful information for developing targeted management strategies to improve and prolong functional speech in individuals with ALS.

First molecular detection of Neospora caninum from naturally infected slaughtered camels in Tunisia.

Background Neospora caninum has been documented to infect most domestic wildlife but is known to primarily infect dogs and cattle and is considered an important cause of abortion in camels.ObjectiveThe aim of this study was to estimate the molecular detection of Neospora caninum in tissues of naturally infected camelids.MethodsBrain, tongue (bottom and tip) and masseter muscles from 35 slaughtered camelids from Tataouine and Médenine regions were collected (n = 140 samples). PCR was used to amplify and detect N. caninum DNA in tissues samples followed by sequencing of some PCR products. A phylogenetic tree was then constructed to compare the partial sequences of the ITS1 gene with GenBank sequences. Histopathology examination was used to detect Neospora spp. cysts, but no lesions were observed.ResultsThe overall molecular detection of N. caninum in camelids was 34.3% (12/35).The highest molecular detection of N. caninum was recorded in animals of more than 3 years old (6/9) and in animals aged between 1 and 3 years old (4/12). Whilst, the lowest molecular detection (2/14) was observed in animals 1 year or younger (p = 0.035).There were no significant differences in molecular detection of N. caninum according to both locality and gender (p > 0.05). Similarly, there was no difference of prevalence between different anatomical locations. Comparison of the partial sequences of the ITS1 gene revealed 100–95.5% similarity among our N. caninum amplicon (MW551566) and those deposited in GenBank.ConclusionThese results highlight the presence of a risk infection by N. caninum in camels. For preventing N. caninum infection further studies are needed to improve our knowledge about the epidemiology of neosporosis in North Africa.

ORAL TUBERCULOSIS: A CASE REPORT

Oral tuberculosis (TB) manifestations are uncommon and usually secondary to pulmonary changes. A 41-year-old male patient presented with the chief complaint of a painful ulcer on tip of his tongue. He reported that the ulcer developed without any remarkable event such as mechanical trauma, vesicle formation, or systemic illness. There was history of cough, fever, and chest pain. Chest x-ray and samples of acid-fast bacilli were positive. A biopsy was performed, and histological finding showed typical findings of oral TB including intense granulomatous inflammatory features with small red rods of mycobacterial organisms as well as epithelioid cells and Langerhans giant cells. After suitable antituberculosis treatments, the oral TB ulcer was almost completely healed after 1 year. We present a case of oral TB affecting the tip of the tongue in a patient with pulmonary TB and emphasize the understanding of intraoral manifestations for early diagnosis and prompt treatment of TB. Oral tuberculosis (TB) manifestations are uncommon and usually secondary to pulmonary changes. A 41-year-old male patient presented with the chief complaint of a painful ulcer on tip of his tongue. He reported that the ulcer developed without any remarkable event such as mechanical trauma, vesicle formation, or systemic illness. There was history of cough, fever, and chest pain. Chest x-ray and samples of acid-fast bacilli were positive. A biopsy was performed, and histological finding showed typical findings of oral TB including intense granulomatous inflammatory features with small red rods of mycobacterial organisms as well as epithelioid cells and Langerhans giant cells. After suitable antituberculosis treatments, the oral TB ulcer was almost completely healed after 1 year. We present a case of oral TB affecting the tip of the tongue in a patient with pulmonary TB and emphasize the understanding of intraoral manifestations for early diagnosis and prompt treatment of TB.