Federal Databases Research Articles

Coal ash resources and potential for rare earth element production in the United States

The renewable energy industry is heavily reliant on rare earth elements, underscoring the need to develop resources and production. The objective of this work was to estimate coal ash resources and potential for extraction of rare earth elements using data for the US. Data on spatiotemporal variability in coal ash resources and disposition were compiled from various federal databases and rare earth elements levels in ash were compiled from the literature. Results show that ~ 52 gigatons (Gt) of coal were produced in the US (1950–2021). Power plants account for most of the coal use, particularly since 1980. Coal ash (5.3 Gt) represents a mean of 10% of coal by weight, ranging from 6% for subbituminous to 14% for lignite. About 70% of coal ash is potentially accessible for rare earth element extraction (1985–2021) and was disposed in landfills and ponds with the remaining coal ash used onsite or sold. Median values of total rare earth elements are much higher in ashes derived from the Appalachian Basin (median 431 mg/kg) than in the Illinois (282 mg/kg) or Powder River basins (264 mg/kg). Considering the market value of rare earth oxides, potentially accessible ash volumes, and percent rare earth element extraction (30% Appalachian and Illinois Basins; 70% Powder River Basin) results in an estimated $8.4 billion value. This study provides fundamental information on accessible coal ash resources in the US, linkages to coal sources, and preliminary estimates of rare earth element levels for future development within the US.

The Steep Decline in Reporting to the National Practioner Data Bank, and a Look at Reporting Levels from “Plaintiff-Favorable” and “Defendant-Favorable” States

The establishment of the National Practitioner Data Bank (NPDB) was authorized in the Health Care Quality Improvement Act of 1986, and it mandated a federal database to collect information related to adverse actions initially against just physicians and dentists throughout the United States, including payments from malpractice lawsuits, restrictions on clinical privileges by hospitals, and medical licensure limitations and revocations by state licensing boards. The aggregate data reports made by this federal data bank began in 1991. The reporting level for the first ten years remained relatively stable in the nationwide range of 16,000 to 18,000 reports per year, but then a steady decline occurred over the second and third decades to under 8,000 reports per year by the year 2021. The researchers in this study explored a theory that might explain at least part of the drop in the states’ reporting levels. That is, states that could be called “Plaintiff-Favorable” (Arizona, Kentucky, New York, Pennsylvania, and Washington) would demonstrate a lesser rate of decline or even an increase in the reporting levels, and states that could be characterized as “Defendant-Favorable” (California, Michigan, Nevada, North Carolina, and Texas) would demonstrate a comparatively greater rate of decline in the reporting levels. The decline in reporting to the NPDB proved fairly consistent for both Plaintiff-Favorable and Defendant-Favorable states. The larger question as to why there occurred an overall negative trend in reporting to the NPDB across the United States during the second and third decades remains an intriguing area for future exploration.

Future warming of the Gulf of Oman: SST trends under contrasting climate scenarios by 2050

This study investigated potential changes in sea surface temperature (SST) within the Gulf of Oman over the next three decades (2020–2050) under contrasting climate scenarios. Monthly SST data from three Coupled Model Intercomparison Project Phase 6 (CMIP6) models were obtained from the Earth System Grid Federation (ESGF) database for a defined spatial grid (0.5° x 0.5°) encompassing the Gulf of Oman. Future changes (2020–2050) in SST were analyzed under two contrasting Shared socioeconomic Pathways (SSPs): SSP245 (optimistic) and SSP585 (pessimistic).A time series analysis employing a weighted average approach across all three models was conducted. This analysis revealed a projected increase in SST for most seasons and months, except for summer. Further trend analysis was performed using the non-parametric Mann-Kendall test and Sen's slope estimator. This analysis indicated a moderate warming trend in the Gulf of Oman's SST over the next 30 years, with an average increase of approximately 1°C. Spatial analysis of SST was also conducted, identifying minimum and maximum temperature values in shallow regions, the Strait of Hormuz, and its connection to the Persian Gulf. The findings of this study suggest a potential for significant warming in the Gulf of Oman over the coming decades, with implications for regional marine ecosystems and weather patterns. Understanding these projected changes is crucial for informing adaptation strategies and mitigating the potential negative impacts of climate change in the region.

Are There Hidden Adverse Events in Hypoglossal Nerve Stimulation: Comparing Social Media and a Federal Database.

Hypoglossal nerve stimulation (HNS) can be an effective treatment for moderate to severe obstructive sleep apnea (OSA) in positive airway pressure (PAP) intolerant patients. To better understand patient experiences with HNS therapy, we explored reported events from HNS-related Facebook groups and the Manufacturer and User Facility Device Experience (MAUDE) database. A retrospective analysis of HNS-related Facebook posts from three groups pertaining to HNS therapy, from October 1, 2022 to October 1, 2023, was performed. Posts were analyzed for patient-reported adverse events. Concurrently, the MAUDE database was reviewed for HNS-related events during the same timeframe. From 737 Facebook posts, 132 (17.55%) adverse events were identified. Adverse events included pain (34.85%), stimulation discomfort (14.39%), lip weakness (6.82%) and issues related to lead tethering or tight leads around the neck (3.79%). Analysis of the MAUDE database found 428 adverse events, including pain (24.07%), lip weakness (0.44%), and lead tethering (1.64%). Facebook group members reported higher rates of lip weakness and lead tethering than recorded in the MAUDE database. These findings illustrate how diverse data sources, such as social media, can enhance our understanding of patient experiences and identify gaps in patient education with HNS therapy. NA Laryngoscope, 2024.

Пути повышения эффективности федеральной базы данных геномной информации

The article analyzes the existing structure of the federal genome information database, issues of registration and screenings. The authors show the existing shortcomings and ways to eliminate them.

ДНК-баркодинг как метод генетической идентификации личности: проблемы и перспективы

The article analyzes opportunities of using the method of DNA identifi cation of an individual with the help of genetic barcoding within corruption combating activities. The author describes principles of digitizing genetic information to create a genetic barcode for further registration in the database. The paper also reviews problems of the development of a federal genome information database based on SNP analysis.

Prevalence and trends in polypharmacy and excessive polypharmacy: a retrospective national database analysis (2012-2021).

Polypharmacy is a growing concern, impacting patient safety and healthcare costs. Monitoring its prevalence and temporal trends is essential for effective healthcare management. This study aimed to determine prevalence and trends of polypharmacy and excessive polypharmacy in Belgium. Utilizing a federal claims database, medication data were analyzed from 2012 to 2021. Polypharmacy (≥ 5 medications) and excessive polypharmacy (≥ 10 medications) were evaluated, with prevalence calculated per 1000 inhabitants, and reported per year, age group and region. Linear regression estimated the impact of age and year on polypharmacy prevalence. In 2021, polypharmacy and excessive polypharmacy were reported in 135/1000 and 31/1000 Belgians respectively. Prevalence of both increased steadily from 2012 to 2021, with excessive polypharmacy rising more prominently. Among adults aged ≥ 65years, prevalence rates were higher, with polypharmacy at 434/1000 and excessive polypharmacy at 106/1000. Regional variations were observed, with prevalence highest in the Walloons region. Patient age and year (2012-2021) were associated with both polypharmacy and excessive polypharmacy (p < 0.001). We observed increases in polypharmacy and excessive polypharmacy over a decade in Belgium, particularly among older adults. Efforts to monitor, manage, and optimize medication use are imperative to ensure safe and effective healthcare delivery.

Development of a regional-based predictive model of incidence of traumatic spinal cord injury using machine learning algorithms

ObjectiveTo develop a predictive model of incidence of traumatic spinal cord injury (TSCI). MethodsThe data for training the model included both the incidence data and the covariates. The incidence data were extracted from systematic reviews and the covariates were extracted from data available in the international road federation database. Then the feature processing measures were taken. First we defined a hyper-parameter, missing-value threshold, in order to eliminate features that exceed this threshold. To tackle the problem of overfitting of model we determined the Pearson correlation of features and excluded those with more than 0.7 correlation. After feature selection three different models including simple linear regression, support vector regression, and multi-layer perceptron were examined to fit the purposes of this study. Finally, we evaluated the model based on three standard metrics: Mean Absolute Error, Root Mean Square Error, and R2. ResultsOur machine-learning based model could predict the incidence rate of TSCI with the mean absolute error of 4.66. Our model found “Vehicles in use, Total vehicles/Km of roads”, “Injury accidents/100 Million Veh-Km”, “Vehicles in use, Vans, Pick-ups, Lorries, Road Tractors”, “Inland surface Passengers Transport (Mio Passenger-Km), Rail”, and "% paved” as top predictors of transport-related TSCI (TRTSCI). ConclusionsOur model is proved to have a high accuracy to predict the incidence rate of TSCI for countries, especially where the main etiology of TSCI is related to road traffic injuries. Using this model, we can help the policymakers for resource allocation and evaluation of preventive measures.

User Experience of Access to Sexual Assault Nurse Examiner and Emergency Contraception in Emergency Departments in the United States: A National Survey.

Despite the prevalence of sexual assault presentations to emergency departments (ED) in the United States, current access to sexual assault nurse examiners (SANE) and emergency contraception (EC) in EDs is unknown. In this study we employed a "secret shopper," cross-sectional telephonic survey. A team attempted phone contact with a representative sample of EDs and asked respondents about the availability of SANEs and EC in their ED. Reported availability was correlated with variables including region, urban/rural status, hospital size, faith affiliation, academic affiliation, and existence of legislative requirements to offer EC. Over a two-month period in 2019, 1,046 calls to hospitals were attempted and 960 were completed (91.7% response rate). Of the 4,360 eligible hospitals listed in a federal database, 960 (22.0%) were contacted. Access to SANEs and EC were reported to be available in 48.9% (95% confidence interval [CI] 45.5-52.0) and 42.5% (95% CI 39.4-45.7) of hospitals, respectively. Access to EC was positively correlated with SANE availability. The EDs reporting SANE and EC availability were more likely to be large, rural, and affiliated with an academic institution. Those reporting access to EC were more likely to be in the Northeast and in states with legislative requirements to offer EC. Our results suggest that perceived access to sexual assault services and emergency contraception in EDs in the United States remains poor with regional and legislative disparities. Results suggest disparities in perceived access to EC and SANE in the ED, which have implications for improving ED practices regarding care of sexual assault victims.

The Regional Labor Market in the Field of Tourism and the Hotel Industry in the Context of the Transformation of the Russian Economy

The relevance. The departure of foreign companies, combined with the growth of domestic demand, has created positive prerequisites for the development of domestic hotel chains and domestic tourism. These objective processes have led to the need to assess the labor market in the tourism and hotel industry in order to identify problems and ways to solve them with the increasing demand of enterprises in this field for qualified specialists. The purpose of the study is to study and analyze the current situation and problems in the labor market in the tourism and hotel industry of the Kursk region. The objectives were to assess the job market in the region, requests and offers from employers, the structure of vacancies and the activity of applicants. Methodology. The research methodology is based on the analysis of statistical information contained in the all-Russian federal database of vacancies and resumes of specialists in the tourism and hotel industry. Results. The data of Russian online recruitment platforms are analyzed and systematized. Based on the results of the analysis of the composition and structure of the labor market of specialists in the hospitality sector, the comparison of supply and demand indicators in it, the analysis of wages in the field under consideration and the dynamics of its change, measures were proposed, the implementation of which will ensure the sustainable development of the industry. Conclusions. Despite some problems and shortcomings in the hospitality sector of the Kursk region, this industry continues to develop and grow. With the growing number of tourists and an increase in the volume of services provided, the labor market in this area is becoming more competitive and attractive for qualified specialists. Regular monitoring of the labor market and analysis of changes in personnel qualification requirements will improve the quality of services provided and meet the growing demand for hospitality workers.

Influence of Climatic and Geographical Features of the Subjects of the Russian Federation on the Activities of Fire Departments

Introduction. When determining the number and technical equipment of fire departments, regulatory documents on fire safety do not take into account natural, climatic and geographical features of the subjects of the Russian Federation in an explicit form. At the same time, there is some information in scientific literature about the influence of certain natural and climatic factors on the effectiveness of fire protection actions in extinguishing fires. The aim of this study was to determine the influence of the system of natural, climatic and geographical characteristics of the subjects of the Russian Federation on the rapid response indicators of territorial fire departments. The results obtained are recommended for further use in rationing the number and technical equipment of fire departments.Materials and Methods. A factor analysis of statistical data for 2020–2022 was carried out. The statistical data were obtained from the Federal State Information System "Federal Database "Fires", from the website of the Federal State Statistics Service of the Russian Federation and from other sources. For the analysis, the authors selected ten indicators characterizing natural, climatic and geographical features of the subjects of the Russian Federation, two indicators of the rapid response of territorial fire departments and four indicators of the fire situation.Results. Five significant factors were identified, the change of which explained the change in the observed indicators. The first factor characterized the relationship of climatic conditions with fire situation indicators. The second factor connected the indicators of the rapid response of fire departments with the terrain features of the subjects of the Russian Federation. The third factor described the relationship between fire situation indicators and rapid response indicators with population density and forest cover of the territory. Other factors did not significantly contribute to the indicators of fire situation and rapid response.Discussion and Conclusion. By means of mathematical analysis and factor modeling, the authors investigated the interdependence of natural, climatic and geographical features of the subjects of the Russian Federation, fire situation indicators and indicators of rapid response of fire departments. The most significant factors influencing these indicators were identified. They included the average air temperature, the area covered by forest, the presence of mountain ranges, and population density. These indicators should be taken into account when determining the number and technical equipment of fire departments to increase the efficiency of their functioning.

Association of Head Injury, Neck Injury or Acoustic Trauma on Phenotype of Ménière's Disease.

The aim of the present study was to investigate adverse effects of head injury, neck trauma, and chronic noise exposure on the complaint profile in people with Ménière's disease (MD). The study used a retrospective design. Register data of 912 patients with MD from the Finnish Ménière Federation database were studied. The data comprised case histories of traumatic brain injury (TBI), neck trauma and occupational noise exposure, MD specific complaints, impact related questions, and the E-Qol health-related quality of life instrument. TBI was classified based on mild, moderate, and severe categories of transient loss of consciousness (TLoC). The mean age of the participants was 60.2 years, the mean duration of the disease was 12.6 years, and 78.7% were females. Logistic regression analysis, linear correlation, and pairwise comparisons were used in evaluating the associations. 19.2% of the participants with MD had a history of TBI. The phenotype of participants with TBI was associated with frequent vestibular drop attacks (VDA), presyncope, headache-associated vertigo, and a reduction in the E-QoL. Logistic regression analysis explained the variability of mild TBI in 6.8%. A history of neck trauma was present in 10.8% of the participants. Neck trauma associated with vertigo (NTwV) was seen in 47 and not associated with vertigo in 52 participants. The phenotype of NTwV was associated with balance problems, VDA, physical strain-induced vertigo, and hyperacusia. Logistic regression analysis explained 8.7% of the variability of the complaint profile. Occupational noise exposure was recorded in 25.4% of the participants and correlated with the greater impact of tinnitus, hyperacusis, and hearing loss. Neither the frequency, duration, or severity of vertigo or nausea were significantly different between the baseline group and the TBI, NTwV, or noise-exposure groups. The results indicate that TBI and NTwV are common among MD patients and may cause a confounder effect.

The Transaction Costs of the Administrative Presidency: Evidence From a Trump-Era Clean Water Act Enforcement Reduction

Over the last two decades, political polarization has gridlocked federal congressional capacity to meet environmental regulatory demands. As a result, presidential authority has expanded to overcome this legislative impediment leading to a new era of “administrative presidency.” In this new era, presidents have increasingly used their administrative authority to meet politically driven environmental goals. Yet, we still know little about how federal-level executive political actions impact the outcomes and operations of local regulatory environmental systems. This study fills this scholarly void by empirically testing the effect of a federal COVID-19 Clean Water Act (CWA) enforcement reduction on Safe Drinking Water Act (SDWA) implementation outcomes for local community water systems (CWSs) sourcing from surface waters (SWs). Using a framework grounded in transaction cost federalism, we argue that a politically motivated executive reduction in federal CWA enforcement is associated with poor local SDWA implementation outcomes. We test this assumption with a differences-in-differences econometric approach using data drawn from the federal Safe Drinking Water Information System database. Our findings suggest that the CWA enforcement reduction resulted in an over 50% increase in SDWA health violations by CWSs sourcing from SWs. The implications of this study extend to U.S. water policy and environmental federalism, highlighting the need for better coordination between the CWA and SDWA and the potential risks associated with relying on broadened executive actions to drive U.S. environmental policy. Further research is warranted to understand the consequences of administrative policy changes on U.S. environmental governance.

Developments and applications of the OPTIMADE API for materials discovery, design, and data exchange.

The Open Databases Integration for Materials Design (OPTIMADE) application programming interface (API) empowers users with holistic access to a growing federation of databases, enhancing the accessibility and discoverability of materials and chemical data. Since the first release of the OPTIMADE specification (v1.0), the API has undergone significant development, leading to the v1.2 release, and has underpinned multiple scientific studies. In this work, we highlight the latest features of the API format, accompanying software tools, and provide an update on the implementation of OPTIMADE in contributing materials databases. We end by providing several use cases that demonstrate the utility of the OPTIMADE API in materials research that continue to drive its ongoing development.

Retrospective Analysis of Spontaneous Reports of Fatal Adverse Reactions Associated with Lidocaine

SCIENTIFIC RELEVANCE. Pain and pain relief are among the most important problems that arise during medical procedures. Lidocaine is used not only as an anaesthetic during interventions but also as a diluent for other medicinal products. Analysis of adverse drug reactions (ADRs) associated with lidocaine contributes to studying lidocaine toxicity and, as a result, developing measures to reduce side effects.AIM. The authors aimed to conduct a retrospective analysis of spontaneous reports of fatal ADRs associated with lidocaine.MATERIALS AND METHODS. This study analysed spontaneous ADR reports of fatal outcomes associated with lidocaine submitted to the federal ADR database in the Automated Information System of the Federal Service for Surveillance in Healthcare of the Russian Federation (Pharmacovigilance, versions 1.0 and 2.0) from 1 January 2008 to 31 December 2020.RESULTS. The ADR reports included 102 fatal outcomes associated with lidocaine. Most often, lidocaine was prescribed as a local anaesthetic or as a diluent for antibacterials. Studying the administered lidocaine doses, the authors identified several overdose cases. Most life-threatening conditions were due to hypersensitivity reactions of anaphylactic shock (54 cases, 52.9%). Lidocaine administration was accompanied by loss of consciousness, respiratory failure, and cardiac arrest in 10 cases (9.8%). Convulsions were a significant clinical sign in 9 cases (8.8%).CONCLUSIONS. Awareness of the risks of systemic toxic effects of local anaesthetics, including lidocaine, necessitates the practical implementation of certain safety measures, such as allergy skin tests before administration and mandatory monitoring of doses and patients’ well-being after administration.

Analysis of Water Consumption during Fire Extinguishing at Objects of Different Functional Fire Hazard Classes

Introduction. Fire-fighting water supply systems play a primary role in ensuring effective fire extinguishing. Many researchers both in our country and abroad have considered the requirements for fire-fighting water supply and problematic issues in this area. At the same time, in order to update the requirements for fire-fighting water supply, it is necessary to study the actual water consumption on fires, taking into account the characteristics of fire objects. The aim of this research was to analyze the water consumption for outdoor firefighting depending on the characteristics of the fire object and compare the actual water consumption with the requirements of regulatory documents on fire safety. Methods and Materials. The authors used statistical data on fires in the Russian Federation for 2019–2021 from the federal state information system "Federal Database "Fires". Methods of statistical data analysis and classification of statistical data were used to determine the actual water consumption for outdoor firefighting, depending on the class of functional fire hazard of the fire object. Visualization of the obtained results was performed by the method of graphical representation of data in the form of histograms and pie charts. Results. The analysis showed that the highest average water consumption was required for objects of the functional fire hazard class F1.2 "hotels, dormitories (with the exception of apartment-type dormitories), dormitory buildings of sanatoriums and rest homes of general type, campsites" — 10.7 l/s. For apartment buildings, the highest average water consumption was required to extinguish fires that had arisen in the attic — 10 l/s and in the garret — 9.2 l/s. Discussion and Conclusion. The results of the analysis can be used to clarify the requirements for water consumption for outdoor firefighting, depending on the functional fire hazard class of the object and the number of floors of buildings. In order to meet these requirements, regular monitoring of fire-fighting water supply systems is required, as well as timely maintenance and repair of external and internal fire-fighting water supply systems.

An Approach to Assessing the Influence of Environmental and Occupational Cancer Hazard Identification on Policy Decision-Making.

Cancer hazard identification is critical to informing decisions on preventive actions. However, the influence of cancer hazard assessments on the creation of health-protective regulations is poorly understood. Although prior studies have measured the health and economic benefits of regulatory actions in general, we are not aware of efforts to explicitly study the influence of cancer hazard identification on policy decisions in the United States. In this commentary, we present an approach to examine whether formal identification of a substance as a human carcinogen may prompt a regulatory action to reduce exposure to carcinogens and enhance public health. Further, we discuss the broader implications of cancer hazard identification on policy decision-making, including identifying gaps and providing recommendations. Using the Report on Carcinogens (RoC) as a test case, we systematically searched U.S. federal and state databases for notices of regulations mentioning the RoC from 1995 to 2023. For each regulation, we extracted information on the carcinogen(s) regulated, the regulatory agency, the regulatory purpose, the economic sector exposure sources, and the analyzed public health benefits and costs. We created a publicly available, web-based interactive tool to visualize the data. U.S. regulatory agencies have been using cancer hazard evaluations, such as the RoC, for decades to inform public health policy actions to prevent or mitigate cancer risks. Specifically, nonregulatory cancer hazard assessments have been used to prioritize chemical evaluations, support regulatory-based assessments, and trigger regulatory action. Our approach showed that assessing the influence of cancer hazard identification on science-based public health policies is feasible, informative, and needed, and our study is a first step in this direction. We recommend expanding this approach to other cancer and noncancer hazard assessments to ultimately inform our understanding of the influence of hazard classifications on policymaking. https://doi.org/10.1289/EHP12681.

A community focused approach toward making healthy and affordable daily diet recommendations.

Maintaining an affordable and nutritious diet can be challenging, especially for those living under the conditions of poverty. To fulfill a healthy diet, consumers must make difficult decisions within a complicated food landscape. Decisions must factor information on health and budget constraints, the food supply and pricing options at local grocery stores, and nutrition and portion guidelines provided by government services. Information to support food choice decisions is often inconsistent and challenging to find, making it difficult for consumers to make informed, optimal decisions. This is especially true for low-income and Supplemental Nutrition Assistance Program (SNAP) households which have additional time and cost constraints that impact their food purchases and ultimately leave them more susceptible to malnutrition and obesity. The goal of this paper is to demonstrate how the integration of data from local grocery stores and federal government databases can be used to assist specific communities in meeting their unique health and budget challenges. We discuss many of the challenges of integrating multiple data sources, such as inconsistent data availability and misleading nutrition labels. We conduct a case study using linear programming to identify a healthy meal plan that stays within a limited SNAP budget and also adheres to the Dietary Guidelines for Americans. Finally, we explore the main drivers of cost of local food products with emphasis on the nutrients determined by the USDA as areas of focus: added sugars, saturated fat, and sodium. Our case study results suggest that such an optimization model can be used to facilitate food purchasing decisions within a given community. By focusing on the community level, our results will inform future work navigating the complex networks of food information to build global recommendation systems.

A revisit of drugs and potential therapeutic targets against non-alcoholic fatty liver disease: learning from clinical trials.

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease, with a worldwide prevalence of 25%. Although numerous clinical trials have been conducted over the last few decades, an effective treatment has not been approved yet. Extensive research has accumulated a large amount of data and experience; however, the vast number of clinical trials and new therapeutic targets for NAFLD make it impossible to keep abreast of the relevant information. Therefore, a systematic analysis of the existing trials is necessary. Here, we reviewed clinical trials on NAFLD registered in the mandated federal database, ClinicalTrials.gov, to generate a detailed overview of the trials related to drugs and therapeutic targets for NAFLD treatment. Following screening for pertinence to therapy, a total of 440 entries were identified that included active trials as well as those that have already been completed, suspended, terminated, or withdrawn. We summarize and systematically analyze the state, drug development pipeline, and discovery of treatment targets for NAFLD. We consider possible factors that may affect clinical outcomes.Furthermore, we discussed these results to explore the mechanisms responsible for clinical outcomes. We summarised the landscape of current clinical trials and suggested the directions for future NAFLD therapy to assist internal medicine specialists in treating the whole clinical spectrum of this highly prevalent liver disease.

Оценка пожарных рисков в Российской Федерации в целом и её мегаполисах на примере Москвы и Санкт-Петербурга, 2009–2021 гг.

Summary. The purpose of the study is, in connection with the change in the procedure for statistical recording of fires, to assess their health consequences in the Russian Federation as a whole and its megacities using the example of Moscow and St. Petersburg for 13 years (2009–2021). Materials and methods of research. Data on the number of fires was taken from the Federal Database “Fires” [https://sites.google.com/site/statistikapozaro/]; population size – on the Rosstat website [https://rosstat.gov.ru/]. Retrospectively, fire statistics since 2009 have included fires. The results of the study were checked for normal distribution of characteristics. The dynamics of indicators was studied using the analysis of time series, for which a 2nd order polynomial trend was used, etc. Research results and their analysis. As a result of the study, the following risks were calculated for the population of the Russian Federation as a whole, Moscow and St. Petersburg: the risk of being caught in a fire; risk of dying in a fire; risk of injury in a fire; individual risk of dying in a fire per 100 thousand population; individual risk of injury in a fire per 100 thousand population. Conclusions: As a rule, the magnitude of individual fire risks in megacities, due to the coordinated work of fire crews during fire fighting, evacuation of people and a number of other circumstances, was less than in the Russian Federation as a whole; there is also a downward trend. The individual risk of death in a fire in Moscow and St. Petersburg was low for Russia; in Moscow the individual risk of injury was low, in St. Petersburg it was average. The calculated new fire risks can be used when carrying out more targeted work to reduce them in the regions of the Russian Federation.