Federal State Unitary Enterprise Research Articles

Retail pharmacy in the structure of the medical organization

Introduction. The changing conditions of the pharmaceutical business, including changes in the legal and regulatory framework, squeeze state enterprises out of the market, which significantly affects the current health care system as a whole and requires non-standard management decisions – organizing retail trade of drugs and medical products in the medical institutions. Purpose of the study . Starting a retail pharmacy in the medical institution effectiveness evaluation, analysis of the project payback period, prospective modeling of indicators. Material and methods . The studies were carried out according to the results of the analysis of the health care system of FMBA of Russia in Zelenogorsk, which provides medical and pharmaceutical services to 64 000 people living in the city from 2005 to 2018. Results and discussion . A retrospective analysis of the activities of FSUE Federal State Unitary Enterprise Pharmacy № 42 in Zelenogorsk city allows identifying deficiencies in drug supply after the reorganization of the state enterprise during the period of market economy establishment. To solve the problems patients face, it is advisable to obtain a pharmaceutical license for retail trade and open pharmacy retail store in the polyclinics in order to implement an immediate drug supply and provide outpatient departments with the required treatment supplies. The break-even point of such business projects is proved by the example of the Federal State Budgetary Institution Federal Siberian Clinical Center FMBA of Russia (FSRCC FMBA of Russia). There are already four pharmacy retail stores functioning in each of the clinics of FSRCC FMBA of Russia in Krasnoyarsk.

ОСНОВНЫЕ ИТОГИ И ПЕРСПЕКТИВЫ СЕМЕНОВОДСТВА КОРМОВЫХ ТРАВ В ФГУП «ПОЙМА»

Presents the historical aspects and the current state of breeding and seed production in the Federal State Unitary Enterprise "Poima", as well as the prospects for the production of seeds of forage herbs, including their higher reproduction in order to provide farmers and other consumers with high-quality seed. The stages of seed production of perennial grasses in the economy are reflected, the analysis and the importance of seed production for agricultural production, as well as prospects. Special attention is paid to the creation and reproduction of high-yielding varieties of perennial grasses for floodplain conditions, such as awnless brome, fescue, timothy-grass, cocksfoot and other species. It is noted that the special variety of fescue meadow hayfields and pasture ecotype Krasnopoimskaya 92, well adapted to the conditions of flooding in the underground conditions, as well as when growing it on watershed areas, is of great importance in modern conditions of forage production. The article also notes a great prospect of developing tetraploid variety of ryegrass annual Rapid in the system of feed production in floodplain conditions, which can replace to a large extent in the Central, Northern and North-Western regions of unstable productivity of corn, even its early-maturing hybrids. In addition, the publication presents the basic agrotechnical methods of cultivation of seeds of such most sought-after perennial grasses as perennial ryegrass, festulolium, fescue reed, allowing them to obtain high and stable yields.

Russia’s Public Sector and Privatization Policy in 2018

From 2016, statistical data began to be published in the framework of the System of Public Property Management Efficiency Estimates. It was approved by Decree of the RF Government No 72 dated January 29, 2015, and introduced by way of replacing the public sector monitoring data, collected and released by the Federal State Statistics Service (Rosstat) since the early 2000s in accordance with the provisions stipulated in RF Government Decree No. 1 dated January 4, 1999 (as amended on December 30, 2002). Among other things, the System contains data on the number of federal state unitary enterprises (FSUEs) and joint-stock companies (JSCs) with RF stakes in their capital. Previously, such data were usually published as part of government privatization programs (from 2011 – for three-year period, and prior to 2011 – for one-year period). In the current Forecast Plan (Program) of Federal Property Privatization and the Main Directions of Federal Property Privatization for 2017–2019, relevant data are available only as of early 2016 (Table 1), and so in order to describe the processes taking place over the period 2016–2018, one must rely on data in the System of Public Property Management Efficiency Estimates.

Effect of Organoclay on the Properties of Vulcanized Siloxane Rubber of the Brand SKTFV-803

The effectiveness of the use of the organoclay of the Cloisite 30B brand of the Southern Clay Products company (USA), which is a Na+-montmorillonit, modified by methylalkyldi (2-hydroxyethyl) ammoniumchloride, and of the organoclay of the Katamin AB, produced by the Federal State Unitary Enterprise CNIIgeolnerud (Russia), modified by alkylbenzyldimethylammoniumchloride on the properties of vulcanized dimethylphenylvinylsiloxane rubber of the brand SKTFV-803 was studied. It was established that the adding of organoclay in the amount of 5 parts by weight in siloxane rubber increased heat resistance, slightly reduced the swelling index in toluene, and, most importantly, was not impair the frost resistance of obtained siloxane HYPERLINK "https://www.multitran.ru/c/m.exe?t=598817_1_2&s1=%F0%E5%E7%E8%ED%E0" vulcanizates.

SANITARY-HYGIENIC CHARACTERISTICS OF THE AREA OF POSITIONING FOR THE DISPOSAL OF ROCKET TECHNICS

There was executed the sanitary-hygienic assessment of residential areas in the zone of possible impact of industrial activity of the Center for the elimination of Intercontinental ballistic missiles affiliated to the Federal State Unitary Enterprise “Center for Operation of Ground-Based Space Infrastructure Facilities” located in the Nizhny Novgorod region. There were performed full-scale studies of air samples, water reservoirs and sources of drinking water, the soil on the content of components of liquid rocket fuels and their degradation products. Studies have shown full-time work enterprises not to be accompanied by the emission of unsymmetrical dimethyl hydrazine, Tetramethyl-2-tetrazene, NDMA into the environment. In samples of water from open stagnant water bodies there was detected both dimethylamine in concentrations exceeding MPC by 1.1 - 1.3 times, and formaldehyde in the concentration below the MAC. All soil samples also contain FA and DMA in concentrations significantly lower than the MPC. As, Be, Cd, Pb in drinking water was not detected within the sensitivity of the method, Ni content, Zn, Mg, Mn, Al does not exceed hygienic standards. Fe content in the water of centralized water supply amounted to 1.5 MAC.

ИСПОЛЬЗОВАНИЕ СЕЛЕКЦИОННЫХ ИНДЕКСОВ В ПЛЕМЕННОЙ РАБОТЕ

The aim of the study is to develop an effective selective index adapted to the conditions of the country, taking into account the national priorities of consumption of livestock products. Selection indices, which are widely used in de-veloped countries with high scientific and production potential in the field of animal husbandry, have been ana-lyzed. They can be divided into three groups. The first group includes five countries where a simplified version of the calculation of selective indices is used. The second group includes nine countries, which are rather complex for on-line analysis of the selection indices. The third group included countries in the breeding work of which com-bined breeding indices are used. The rating of the most valuable bulls of the Federal state unitary enterprise «Mos-kovskoye» on breeding work made with application of the most widespread selection indexes is given. Selection indices, with the similarity of the methods of their calculation, need some adjustment to be used in our country. A selection index is developed and presented under the name UI (combined index). The developed index UI in 83% of cases coincides with the index ASI (Australia), in the remaining 17% of cases the difference does not exceed 0.5 rank. With the index PIN (England) differences are more significant, in 34% of cases there is a complete coinci-dence of estimates, in 
 50% – the differences are only 1 rank and only in one case the discrepancy is significant enough. The index of INET (the most frequently used by breeders in Europe) coincides with the evaluation of breeding value of animals in 100% of cases. The new index is supposed to be used in the work with dairy breeds.

Strategic documents to define the role of the libraries

Currently, the creation of strategic documents and the implementation of the action plan to achieve the goals and objectives set out in such documents is widespread among large business companies, both manufacturing and mining sectors, the retail sector, as well as elevated to the rank of mandatory for corporations with state participation, Federal state unitary Enterprises and a number of similar organizations. Such requirements are imposed on a number of sectors of the economy, and the cultural sector, where there are two documents of strategic goal – settingthe Basis of the state cultural policy and the Strategy of the state cultural policy, has not escaped this.It is important that these strategic planning documents, which represent a whole body of normative legal acts defining the goals and directions of the country's development, are of significant legal significance, as they are approved by the Decrees of the President of the Russian Federation or by resolutions and orders of the Government of the Russian Federation, which, in particular, means that they are binding.The article is devoted to the analysis of approaches to the definition of the role of libraries presented in various strategic documents of the Federal level, approved in recent years, which in a General sense can be considered clearly formulated "state order" for the implementation of which the activities of public libraries of the country should be focused in the coming years and in the long term.

Исследование возможности применения диафена ФП, сульфенамида Ц и N,N’-дитиодиморфолина отечественного производства в резиновых смесях взамен импортных аналогов

The article presents the results of a study of various rubber compounds based on rubbers containing, in the composition, made by FGUP GosNIIOHT diafen FP, sulfenamide C and N,N'-dithiodimorpholine instead of imported analogues. Rubber compounds were made on a laboratory rubber mixer SKI-3L with Intermix rotors. After a day at room temperature, the rubber mixtures were vulcanized on a vacuum compression machine of column type a firm Panstone 3RT. The main technological indicators of rubber mixtures after their manufacture on the rolls were: ductility, ring modulus and density. These indicators characterize the processability of rubber mixtures in the manufacture of products from them. For the obtained vulcanizates, the elastic-deformation properties (conditional tensile strength, relative elongation at break, Shore A and ISO hardness, bond strength with metal at tearing, and abrasion resistance) were determined by standard methods. To assess the performance properties of rubbers, changes in conditional tensile strength, relative elongation at break, hardness, volume and mass after rubbers aging in corrosive media, as well as relative residual deformation of compression, temperature limit of brittleness and frost resistance were determined. The possibility of using diaphene FP, sulfenamide C and N,N'-dithiodimorpholine made by FSUE "GosNIIOHT" as part of various rubber mixtures instead of imported analogs is shown. The obtained rubbers according to the technological, elastic-deformation and operational properties comply with the requirements. These rubbers can be used for the manufacture of rubber-technical products with a special set of elastic-deformation and performance properties, and domestic ingredients manufactured by the Federal State Unitary Enterprise GosNIIOHT can be introduced into production.

Оценка качества воды Волжского плеса Куйбышевского водохранилища по состоянию зоопланктона

The object of the study were three different in their hydrological characteristics, as well as the degree of anthropogenic load on them (in the form of sewage from the adjacent territory), the area of the water area of the Volga reaches of the Kuibyshev Reservoir, where there are deposits of nonmetallic building materials. Studies were conducted during the vegetation period 2014-2015. They included physical/chemical studies and studies of the state of zooplankton. Total 311 samples of zooplankton were collected and processed. During the study, 30 species of zooplankton organisms were recorded: 7 species of Rotifera, 7 species of Copepoda and 16 species of Cladocera. The richest in terms of the quantitative diversity of species was No. 3 site. Prevalent in terms of number and biomass of organisms – site number 1. Quantitative indicators of zooplankton were observed in 2015 compared to 2014. This is explained by the fact that 2014 was warmer than 2015. The oxygen regime of 2014 was also better than that of 2015. The turbidity of water in 2014 was below the turbidity of water in 2015, the quality of water in the second year of research deteriorated compared to the first in a number of indicators, such as COD, compounds copper, zinc, manganese, oil products. The mid-vegetation indexes of saprobity for the indicated observation period make it possible to attribute these sections of the Volga reach of the Kuibyshev reservoir to the β-mesosaprobic zone, which corresponds to the third class of water quality - moderately polluted water. Proceeding from the obtained values of the Shannon and Pielu indices, the zooplankton of the studied sections of the Volga reaches of the Kuibyshev reservoir has a rather low species richness with a rigid type of dominance, which characterizes it as mesotrophic. The ratio of groups of organisms and the dominance of individual species indicates a deterioration in water quality over a two-year period of research, which is confirmed by the research conducted by the Federal State Unitary Enterprise «UGMS RT».

Study of the modes of operation of capacitive energy storage in the automobile engine start systems

The article presents data on the study of the operating modes of capacitive energy storage (ES) in the start systems of a modern automobile engine. Experimental dependencies of the main parameters of the electric starter start systems (SSS) using ES are presented. A comparative analysis of alternative energy storage devices revealed that the best performance indicators for specific power are ES, which is achieved due to lower internal resistance. ES are able to quickly give away and accumulate energy. The discharge and charge time is determined by the electricity consumers and the parameters of the charging circuit of ES. Studies of ES in SSS for automotive internal combustion engines (ICE) were carried out, when, instead of the standard battery the battery with a smaller capacity is used, and the ES is located in the remaining part of the volume of battery. At high specific rates of ES, the reliability of the start can be increased with the same total volume and weight of the SSS at low temperatures. The theoretical and experimental studies have allowed to obtain the dependence of the instantaneous and average parameters of the SSS on the time of the engine scrolling, as a result of which the required capacity of the ES and its internal resistance, the initial energy of the ES, as well as the necessary volume and mass of the ES are determined. The volume and mass of batteries can be determined from the reference literature or by known methods by specific energies of batteries in volume and mass. On the experimental dependences it was shown that the time of the crankshaft scrolling, the number of working strokes and the angle of rotation of the crankshaft to a complete stop Nрх depend on the capacity and charge voltage of the ES. The studies were conducted in the Cold Start Laboratory of the Federal State Unitary Enterprise Research and Experimental Institute of Automobile Electronics and Electrical Equipment together with the Department “Electrical Equipment and Industrial Electronics” of Moscow Polytechnic University, where an experimental assessment of the possibility was made of starting gasoline engines at low temperatures of SSS with ES of high-voltage (capacitors with a voltage of 200 V - 290 V) and low-voltage ESs with a voltage of 12 V - 16 V.

Correcting the Semi-Implicit Numerical Scheme Incorporated in the KORSAR Code Two-Liquid Model

Two algorithms used to correct the semi-implicit numerical scheme for time integration of the conservation equations incorporated into the KORSAR/GP computer code two-liquid model are presented. The KORSAR/GP code has been developed jointly by specialists of the Federal State Unitary Enterprise Aleksandrov Research Institute of Technology and Gidropress Experimental Design Office; in 2009, the code was certified at the Federal Service for Environmental, Technological, and Nuclear Supervision (Rostekhnadzor) as applied to numerical safety assessment of VVER-based reactor plants. In the semi-implicit scheme, the convective terms appearing in the phase momentum conservation equations are written in an explicit form. The mass and energy flows of the phases are represented implicitly with respect to phase velocities, and the transferred donor quantities are calculated based on the parameters taken from the previous time layer. Owing to linearization of unsteady and source terms, the linear system of finite difference equations is solved in a noniteration manner. The first of the presented algorithms compensates for numerical imbalances of phase masses and energies resulting from linearization of unsteady terms appearing in the discrete equations and ensures conservativeness of the scheme. The second algorithm introduces correction for the nonphysical redistribution of coolant mass and energy over the computational cells if a change occurs in the phase motion direction within a time step when the scheme of approximating the convective terms becomes “antidonor” with respect to flow. The numerical imbalances and refinements taking into account the correction of donor quantities are computed at each time step according to the proposed correlations and are used for making compensation at the next time step as supplementary sources in the conservation equations. Results from testing the correction algorithms in the KORSAR/GP code are presented. The effectiveness of the imbalance compensation algorithm is confirmed by solving a problem involving the natural circulation loop heating process. The adequacy of the “antidonor” scheme correction algorithm is demonstrated on problems involving steplike initial distribution of the scalar parameters of a stagnant single-phase gaseous or water coolant in a horizontal tube when the flowrate at the tube inlet has different signs at different time steps.

Alloplasmic recombinant lines (H. vulgare)-T. aestivum with 1RS.1BL translocation: initial genotypes for production of common wheat varieties

Alloplasmic lines are formed when the cytoplasm of one species is replaced by the cytoplasm of another as a result of repeated recurrent crosses of wide hybrids with the paternal genotype. Since the cytoplasm replacement results in new intergenomic interactions between a nucleus and cytoplasm leading to variability of plant characteristics, alloplasmic lines with restored fertility can be an additional source of biodiversity of cultivated plants. Earlier, recombinant alloplasmic lines (H. vulgare)-T. aestivumdesignated as L-17(1)–L-17(37) were formed from a plant with partially restored fertility of the BC3 generation of barley-wheat hybridH. vulgare(cv. Nepolegayushchii) ×T. aestivum(cv. Saratovskaya 29). This male-sterile hybrid was consistently backcrossed with wheat varieties Mironovskaya 808 (twice) and Saratovskaya 29, and Mironovskaya 808 had a positive impact on the restoration of fertility. This paper presents the results of investigation into a group of recombinant alloplasmic lines (L-17F4), as well as into doubled haploids (DH) lines – alloplasmic DH-17-lines obtained from anther culture of alloplasmic lines (L-17F2). The most productive of these lines were used as initial breeding genotypes. Hybrid form Lutescens 311/00-22 developed from the crossing of the alloplasmic DH(1)-17 line (as maternal genotype) with euplasmic line Com37 (CIMMYT), the source of the 1RS.1BL wheat-rye translocation, proved to be successful for breeding. The presence of the 1RS.1BL translocation in the genome of the Lutescens 311/00-22 form and the L-311(1)–L-311(6) alloplasmic lines isolated from it did not lead to a decrease of fertility or sterility in the plants. This indicates that the chromosome of the 1BS wheat does not carry the gene(s) that determine the restoration of fertility in the studied (H. vulgare)-T. aestivumalloplasmic lines. Alloplasmic lines L-311(1)–L-311(6) showed their advantage in comparison with the standard varieties for resistance to leaf and stem rust, yield, and grain quality. The breeding tests performed at Omsk Agricultural Scientific Center, Agrocomplex “Kurgansemena”, Federal State Unitary Enterprise “Ishimskoe” (Tyumen Region), using alloplasmic lines L-311(5), L-311(4) and L-311(6) resulted in varieties of spring common wheat Sigma, Uralosibirskaya 2 and Ishimskaya 11, respectively.

Federal Property and Privatization Policy in Russia in 2017

2016 saw first publication of data from a performance measures framework for federal property management that was adopted on January 29, 2015 by Russian Government’s executive order No. 72 in lieu of performance measures for a public sector monitoring conducted by Rosstat in the early 2000s in pursuance of the Russian Government’s executive order No. 1 dated January 4, 1999 (as further amended on December 30, 2002). The performance measures framework contains data for the number of federal state unitary enterprises (FSUEs) and joint-stock companies (JSCs) with government equity participation that were previously published in privatization programs over a 3-year period (since 2011) and one-year period (prior to 2011). A new Forecast Plan (Program) for Federal Property Privatization and Guidelines for Federal Property Privatization for 2017–2019 adopted early in 2017 contains data dated only as of early 2016. As of early 2017, according to the Report of the Federal Agency for State Property Management (hereinafter Rosimushchestvo) on the implementation of privatization program for 2017–2019, the Russian Federation owned 1108 FSUEs and held an interest of 11 and 17 percent in 1416 JSCs and LLCs, respectively, marking a decline from the previous year’s number of economic agents with the same legal form of business. However, developments and processes that took place in 2017 only can be described using data from the performance measures framework for federal property management.

Метод оценки пигментного комплекса древесных растений как индикатор адаптации к засушливым условиям

Актуальность темы исследований связана с подбором адаптированного генофонда деревьев и кустарников для обогащения лесомелиоративных комплексов деградированных ландшафтов в условиях действия стресс-факторов. Опыт интродукции в аридном поясе России показал, что из нескольких тысяч таксонов испытанных деревьев и кустарников способны успешно произрастать чуть более трехсот. Для решения проблемы научно-обоснованного подбора ассортимента для обогащения дендрофлоры с учетом лимитирующих стресс-факторов роста и развития растений в различных экологических условиях необходимо проводить специальные эксперименты с глубоким обобщением и анализом полученных результатов. Результаты эксперимента напрямую зависят от эффективности используемых методов. Цель исследований – провести сравнительную оценку и установить различия в состоянии пигментного комплекса под воздействием стресс-факторов с использованием современного портативного флавонид- и хлорофиллометра DUALEX SCIENTIFIC+. В статье рассмотрена возможность определения устойчивости растительных организмов к стресс-факторам по пигментному комплексу. На основе сравнительной оценки количественных измерений хлорофилла а и b, каротиноидов, антоцианов листьев в полевых условиях с использованием современного портативного флавонид- и хлорофиллометра DUALEX SCIENTIFIC+ выявлены закономерности изменения содержания пигментного комплекса, отражающие адаптационные возможности растений. Объектами исследований являлись представители видового, формового и сортового разнообразия деревьев и кустарников коллекционного фонда ФНЦ агроэкологии РАН, произрастающих в Кластерном дендрологическом парке ВНИАЛМИ (34:34:060061:10; ФГУП «Волгоградское», 34:34:000000:122). Представлен анализ апробации полевого метода оценки пигментного комплекса (хлорофилл а и b, каротиноиды, антоцианы), на базе спектров оптических длин волн в здоровых растениях приемлемый для получения количественных данных в пространственных и временных масштабах. Полученные материалы согласуются с зарубежными исследованиями и отмечают варьирование содержания пигментного комплекса под действием экологических факторов в период вегетации. Установлен диапазон содержания хлорофилла а+б у древесных видов от 11,50 до 46,95 мг/см2. Выявлены различия на действие стресс-факторов (температура воздуха – 34,42-35,48 ºС, влажность воздуха – 15,5-16,0 %) по содержанию флавоноидов (у деревьев от 0,41 до 2,19 мг/см2, кустарников – от 0,82 до 2,08 мг/см2 и антоцианов (от 0,08 до 0,29 мг/см2). Проведенный анализ динамики пигментного комплекса позволил выделить перспективные группы растений (виды, формы, сорта) по их адаптивности к различным неблагоприятным воздействиям окружающей среды. The relevance of the research topic is related to the selection of adapted gene pool of trees and shrubs for the enrichment of forest reclamation complexes of degraded landscapes under the influence of stress factors. The experience of introduction in the arid zone of Russia showed that of several thousand taxa of tested trees and shrubs can successfully grow a little more than three hundred. To solve the problem of scientifically based selection of the range for the enrichment of dendroflora, taking into account the limiting stress factors of plant growth and development in various environmental conditions, it is necessary to conduct special experiments with a deep generalization and analysis of the results. The results of the experiment directly depend on the efficiency of the methods used. The aim of the research is to compare and establish differences in the state of the pigment complex under the influence of stress factors using modern portable flavonide and CHLOROPHYLL dualex SCIENTIFIC+. The article considers the possibility of determining the resistance of plant organisms to stress factors on the pigment complex. On the basis of comparative evaluation of quantitative measurements of chlorophyll a and b, carotenoids, leaf anthocyanins in the field using modern portable flavonide and chlorophyll meter DUALEX SCIENTIFIC+ the regularities of changes in the content of the pigment complex, reflecting the adaptive capacity of plants. Objects of research were representatives of the species, molded and varietal diversity of trees and shrubs collection Fund FNTS Agroecology Russian Academy of Sciences, a Cluster growing in the arboretum Park VNIALMI (34:34:060061:10; Federal state unitary enterprise "Volgograd", 34:34:000000:122). The paper presents an analysis of the field method of evaluation of pigment complex (chlorophyll a and b, carotenoids, anthocyanins) on the basis of optical wavelength spectra in healthy plants acceptable for quantitative data in spatial and temporal scales. The obtained materials are consistent with foreign studies and note the variation in the content of the pigment complex under the influence of environmental factors during the growing season. The range of chlorophyll a+b content in tree species was established from 11.50 to 46.95 mg/cm2. Differences in the effect of stress factors (air temperature-34,42-35,48 ° C, air humidity-15,5 – 16,0 %) in the content of flavonoids (in trees from 0,41 to 2,19 mg/cm2, shrubs-from 0.82 to 2.08 mg/cm2 and anthocyanins (from 0.08 to 0.29 mg/cm2). The analysis of the pigment complex dynamics made it possible to identify promising groups of plants (species, forms, varieties) according to their adaptability to various adverse environmental effects.

IMPACT OF GREEN MANURE ON CROP YIELD OF CEREALS IN CONDITIONS OF IRRIGATION OF THE TERSKO-SULAK SUBPROVINCES

Aim. The aim of the research was to identify the effect of types of fertilizer on increasing soil fertility and corn yield of grain and sorghum in conditions of irrigation of the Tersko-Sulak subprovince. Methods. Carrying out some field experiments: conducting observations and laboratory tests, selection of soil and plant samples was carried out according to generally accepted methods: statistical processing of yield data was carried out by the method of variance analysis based on Kirov Federal State Unitary Enterprise and FSBSI Dagestan Agricultural Research Institute named after F.G. Kisriev. Results. Studies showed that in the post-harvest period after harvesting winter wheat, it is better to cultivate green manure with the presence of legumes. A valuable biological feature of them is the ability to absorb atmospheric nitrogen. The powerful root system of the seeding pea improves the physical properties of the soil, as well as microbiological activity. The most favorable conditions are created for the growth and development of maize and sorghum, after plowing of fertilizers in the stubble period in the conditions of irrigation of the Tersko-Sulak subprovince, by applying mineral fertilizers at a dose of N150 P75 K75, seeding peas, manure (30 t / ha), In these cases, on average, over two years, the highest yield of maize was 5.6-5.7-5.5 t / ha and grain sorghum, respectively, 4.7-4.8-4.5 t / ha. Conclusion. For the first time, in conditions of irrigation of the Tersko-Sulak subprovince, were obtained the results on the effectiveness of different types of fertilizers introduced into the soil.

Evaluation of Co-C, Ni-C, Re-C and δ(MoC)-C Fixed Points Fabricated at KRISS

This paper presents the recent work that has been carried out at the Korea Research Institute of Standards and Science (KRISS) to fabricate and evaluate high temperature eutectic/peritectic fixed points: Co-C, Ni-C, Re-C and δ(MoC)-C fixed points. The research has been conducted as part of an internal research project that aims at fabricating high quality eutectic fixed points and measuring their thermodynamic temperatures with the lowest possible uncertainty. The fabrication procedures and instruments used for fabrication and investigation are described in details. ITS-90 temperatures for the four fixed points measured are presented with a melting range, repeatability, and expanded uncertainty. The Co-C and the Re-C fixed points are compared with those made at All-Russian Research Institute of Optical and Physical Measurements Federal State Unitary Enterprise (VNIIOFI) to validate our works. The results are also presented.

TECHNOLOGY OF OBTAINING POLYRIBOSYLRIBITOL PHOSPHATE AS AN ACTIVE PHARMACEUTICAL INGREDIENT FOR THE PRODUCTION OF POLYSACCHARIDE VACCINES

Despite the world practice, in the Russian Federation immunization against hemophilic infection is carried out only for the children from risk groups, which may be due to the lack of production of this vaccine in the Russian Federation. Therefore, the development of technology for the preparation of polyribosylribitol phosphate (PRP, the active substance of the Hib vaccine) remains relevant. Earlier, the employees of the federal state unitary enterprise “Saint-Petersburg scientific research institute of vaccines and serums and the enterprise for the production of bacterial preparations” of Federal medical and biologic agency of Russia isolated and identified the strain of Haemophilus influenzae SPB type b B-7884. The conditions for cultivation of the strain B-7884 and primary isolation of PRP from the culture liquid were arranged. The aim of the work was to study the possibility of excluding the centrifugation stage for separating H. influenzae SPB type b B-7884 biomass before clarification on the cascade of filter discs, and the development of subsequent stages of PRP isolation from the obtained intermediate product. Materials and methods. PRP isolation from an inactivated culture liquid of strain B-7884 was carried out by centrifugation, filtration, precipitation, homogenization, extraction under various conditions. The concentration of PRP in the intermediate products was determined by the orcinol method, the identity was determined by the latex agglutination test. Results and discussion. The optimal scheme for isolation and purification of the active pharmaceutical ingredient PRP, including filtration through the cascade of deep filters Zeta plus LP 60 (0.3–0.6 μm) and Zeta plus LP 90 (0.1–0.3 μm), concentration and diafiltration on ultrafiltration cassettes with nominal molecular weight cut-off of 30 kDa, precipitation with 10% cetyltrimethylammonium bromide solution (5% v/v), with subsequent homogenization of the obtained precipitate (in the presence of 12.5% of ethanol from the concentrate volume) and extraction (32.5% ethanol), filtration through depth filters Zeta Plus SP 30 and carbon filters Zeta Plus Carbon R53, and precipitation by 1.0% (v/v) 4.0 M sodium chloride solution and freezing at –(20 ± 2)°C, was developed. Conclusion. The obtained results will become the basis for the further development of the polysaccharide substance and allow us to proceed to the next stage in the development of the vaccine against Haemophilus influenzae type b – conjugation with the carrier protein.

Computational Analysis of the Shutdown of One MCP of VVER-1000 During Operation of the Reactor Facility at Nominal Power

The article considers results of the computational analysis of process with a disturbance in the operation of VVER-1000 reactor facility, caused by the de-energizing of a single Main Circulation Pump (MCP-195).Calculations of de-energizing of the MCP were made with the CORSAR/GP software package developed by Federal State Unitary Enterprise "Alexandrov RESE". This software package is a contour code which allows making calculations of emergency situations taking into account the operation of various systems, including safety systems. CORSAR/GP is certified and verified for facilities with water-cooled reactors including VVER-1000.Developed nodalization scheme (computational scheme) of the first circuit of VVER-1000 allows adding or excluding the operation of protective safety systems and can also be used for a computational analysis of other disturbances of normal operation.To perform the calculations parameters of the core were chosen to ensure conservative results for the parameters determining the current state of the reactor facility (fuel temperature, boiling point, etc.).The computational analysis showed that in case of de-energizing of a single MCP when the reactor is operated at nominal power criteria describing the safety of the facility are fulfilled, protective automatic actions of safety systems transfer the reactor facility to a controlled safe state.

К вопросу об особенностях реорганизации Федерального государственного унитарного предприятия «Почта России», основах деятельности акционерного общества «Почта России» и о внесении изменений в отдельные законодательные акты Российской Федерации. Краткий комментарий к Федеральному закону от 29.06.2018 № 171-ФЗ

К вопросу об особенностях реорганизации Федерального государственного унитарного предприятия «Почта России», основах деятельности акционерного общества «Почта России» и о внесении изменений в отдельные законодательные акты Российской Федерации. Краткий комментарий к Федеральному закону от 29.06.2018 № 171-ФЗ

The Public Sector and Privatization Policy

In 2016, statistical data began to be published in the framework of the newly introduced System of Public Property Management Efficiency Estimates. It was approved by Decree of the RF Government of 29 January 2015, No 72 and introduced by way of replacing the public sector monitoring data, collected and released by the Federal State Statistics Service (Rosstat) since the late 1990s in accordance with the provisions stipulated in Decree of the RF Government of January 4, 1999, No 1 (as amended as of December 30, 2002). Among other things, the System of Public Property Management Efficiency Estimates contains data on the number of federal state unitary enterprises (FSUEs) and joint-stock companies (JSCs) with RF stakes in their capital, which previously were published as part of government privatization programs (from 2011 – for three-year period, and prior to 2011- for one-year period.