Federal State Brandenburg Research Articles

Holistic and integrated life cycle sustainability assessment of prospective biomass to liquid production in Germany

As a part of the developing bioeconomy, liquid biofuels may play an important role for transportation due to the hope for a sustainable drop-in alternative to substitute fossil fuels and maintaining existing economic infrastructures. In this case study we applied Holistic and Integrated Life Cycle Sustainability Assessment to a prospective technical concept for the production of biofuels from wood residues, sorghum and straw via gasification and Fischer-Tropsch synthesis located in the German federal state Brandenburg. Through this quantitative and qualitative sustainability assessment we identified synergies and hot-spots of biofuel production on a detailed and aggregated level, as well as compare the impacts to fossil fuels and other alternative transport systems. 99 social, ecological and economic indicator results addressing 14 out of 17 SDGs show contributions but also sustainability risks of such biofuels for the SDGs. The total substitution factor of impacts (f = 21.38) for all indicators of biofuels compared to fossil fuels indicates significantly higher impacts of biofuels production, in particular for land (SDG 15, f = 30.43), water (SDG 14, f = 125.57), consumption and production patterns (SDG 12, f = 54.11), low energy efficiency and maintaining problematic global supply chains and working conditions. However, the impacts on climate can be lower (SDG 13, f = 0.42), if residual heat is effectively and efficiently used. Comparing the transportation systems and use phases of fuels, all types of car-based individual transportation including fossil fuels (f = 6.50), biofuels (f = 9.16) and electric drive (f = 6.46) had significant higher impacts than transportation by train. Besides technological downsides, such as the high energy demand, biofuels may play a minor role for specific applications with no other alternative energy technologies in the future. In conclusion, it is very questionable whether such liquid biofuels are a suitable drop-in solution to substitute fossil fuels in a significant quantity. In a final discussion we referred to the necessary societal-ecological transformation with structural changes of production, consumption, political economy and global supply chains. In the future, Holistic and Integrated Life Cycle Sustainability Assessment will be further improved by closing indicator and database gaps, including a cost analysis and direct stakeholder participation, as well as absolute sustainability assessments on how much biofuel production is sustainable.

Response of Superoxide Dismutase (SOD) to Homogeneous and Heterogeneous Food Sources in Bumblebees (Bombus terrestris) and Honeybees (Apis mellifera)

The conception of “floral strips” is a strategy to provide more and different food sources for pollinators. The impact of “homogeneous” Phacelia tanacetifolia (“Phacelia”) and “heterogeneous” (flower mix) food sources on the enzyme activity of bumblebees (Bombus terrestris) and honeybees (Apis mellifera) under urban conditions has not been reported. Organisms responding to challenging environmental conditions are known to exhibit increases in oxidative stress parameters which in turn affect both physiological and metabolic parameters. A field study was conducted in Berlin-Dahlem, Germany, using the response of the “marker” enzyme superoxide dismutase (SOD) on food sources for assessment. SOD data is also shown from the wild bee Megachile rotundata (Fabricius 1787), obtained from three different locations in the federal state Brandenburg, Germany. The results demonstrate that the enzyme activity of SOD significantly increased in bumblebees visiting the flower mix compared to the Phacelia. The experimental approach had individual effects at the level of the species, bumblebees and honeybees, respectively. The activity of the biomarker SOD could be successfully used to assess the effects of the compositions of homogeneous and heterogeneous flower fields.

Detection of new-onset atrial fibrillation in heart failure patients using daily non-invasive ECG monitoring in the TIM-HF2 telemedicine trial

Abstract Background Heart failure (HF) and atrial fibrillation (AF) impair the prognosis when they occur concomitantly. Recent telemedical studies suggest that HF patients with AF may derive a greater benefit from telemedicine care but the results are inconsistent. The rate of newly detected AF in HF patients by daily non-invasive electrocardiogram (ECG) monitoring is unknown and a possible influence on the outcome of remote patient management (RPM) remains unclear. Purpose We aimed to investigate the detection of new atrial fibrillation in patients assigned to RPM in comparison to patients assigned to usual care (UC) in the TIM-HF2 trial. Methods The prospective, multicentre and controlled TIM-HF2 trial randomised 1538 patients (765 RPM, 773 UC). All patients had a 12-channel ECG at baseline and after one year at the final study visit. Patients who were assigned to RPM additionally transmitted a daily ECG to the telemedical centre (TMC). We excluded all patients with pacemaker including implantable cardioverter defibrillator (ICD) or cardiac resynchronisation therapy (CRT) in the baseline ECG, leaving 879 patients for analysis (RPM: 442 and UC: 437). The patients were stratified into patients with SR and patients with AF according to the rhythm documented at baseline. The primary endpoint of this analysis was newly documented AF within one year after randomisation. We analysed the daily to the telemedical centre transmitted ECGs of patients assigned to RPM with the documented rhythm status of the ECGs performed at the final study visit of patients assigned to UC. Results 569 patients had SR and 310 patients had AF at baseline. The proportion of patients with AF was nearly the same in the RPM (159, 36.0%) and the UC (151, 34.6%) group. 68 patients (24.0%) were detected with new atrial fibrillation in the RPM group compared to 22 patients (7.8%) in the UC trial arm during the one-year follow-up (p<0.001, number needed to screen 6). Conclusion In patients with heart failure and daily ECG transmission, atrial fibrillation was detected three times more frequently in comparison to usual care within one year. Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): The TIM-HF2 study was supported by a research grant of the German Federal Ministry of Education and Research (grant numbers 13KQ0904A, 13KQ0904B, 13KQ1104A). The TIM-HF2 study was a part of the research and development project “Gesundheitsregion der Zukunft Nordbrandenburg – Fontane” (Fontane). The Fontane system was developed in private–public partnership (PPP) supported by research and development grants from the German Federal Ministry of Education and Research, the European Regional Development, and the Federal State Brandenburg.

What makes the difference between memory and face of a landscape? A machine learning approach applied to the federal state Brandenburg, Germany

The paper introduces two types of models: the “memory of a landscape” and the “face of a landscape”. The memory of a landscape refers to the development of a landscape as a result of many small and some major events. It can be described by a multitude of features that are difficult to change by humans, such as the initial geological substrate and the availability of nutrients linked to it. The implementation of the “memory model” leads to a scientific modelling approach that models the influence of the basic factors on forest distribution. The face of a landscape on the other hand implements a Big Data approach. The face can be changed more easily, e.g. by clearing forest areas and converting them into arable land. Both types of models are used to conclude from today’s perspective on the development of historical forests around 1880. A machine learning algorithm is used to implement both model types and evaluate the importance of features. Both models show differences in accuracy and simulation, which are discussed in detail. The inherent evaluation of the importance of the model inputs can be used to critically review some doctrines. The combination of machine learning with the knowledge of experts who help to select and prepare the data can be used in the future to depict the memory of a landscape more comprehensively in a model than is possible with previous approaches.

Evaluating the Use of Prostate-Specific Antigen as an Instrument for Early Detection of Prostate Cancer beyond Urologists: Results of a Representative Cross-Sectional Questionnaire Study of General Practitioners and Internal Specialists

Objectives: The aim of this cross-sectional study was to evaluate the value of prostate-specific antigen (PSA) testing as a tool for early detection of prostate cancer (PCa) applied by general practitioners (GPs) and internal specialists (ISs) as well as to assess criteria leading to the application of PSA-based early PCa detection. Methods: Between May and December 2012, a questionnaire containing 16 items was sent to 600 GPs and ISs in the federal state Brandenburg and in Berlin (Germany). The independent influence of several criteria on the decision of GPs and ISs to apply PSA-based early PCa detection was assessed by multivariate logistic regression analysis (MLRA). Results: 392 evaluable questionnaires were collected (return rate 65%). 81% of the physicians declared that they apply PSA testing for early PCa detection; of these, 58 and 15% would screen patients until the age of 80 and 90 years, respectively. In case of a pathological PSA level, 77% would immediately refer the patient to a urologist, while 13% would re-assess elevated PSA levels after 3-12 months. Based on MLRA, the following criteria were independently associated with a positive attitude towards PSA-based early PCa detection: specialisation (application of early detection more frequent for GPs and hospital-based ISs) (OR 3.12; p < 0.001), physicians who use exclusively GP or IS education (OR 3.95; p = 0.002), and physicians who recommend yearly PSA assessment after the age of 50 (OR 6.85; p < 0.001). Conclusions: GPs and ISs frequently apply PSA-based early PCa detection. In doing so, 13% would initiate specific referral to a urologist in case of pathological PSA values too late. Improvement of this situation could possibly result from specific educational activities for non-urological physicians active in fields of urological core capabilities, which should be guided by joint boards of the national associations of urology and general medicine.

Research on Utilization of Geo-energy

The world's energy demand will increase year by year and we have to search for alternative energy resources. New concepts concerning the energy production from geo-resources have to be provided and developed. The joint project GeoEn combines research on the four core themes Geothermal Energy, Shale Gas, CO2 Capture and Utilization and CO2 Storage. The research is carried out in the federal state Brandenburg in Germany where all project partners - Helmholtz Centre Potsdam, University of Potsdam, Brandenburg University of Technology - and the infrastructures - Schwarze Pumpe, Ketzin, Groß Schönebeck - are located.

Eco-hydrological modelling in a highly regulated lowland catchment to find measures for improving water quality

Water quality modelling in the meso-scale Rhin catchment in the German federal state Brandenburg was done (1) to answer some specific questions concerning identification of point and diffuse sources of nutrient pollution in the catchment, (2) to assess the influences of possible climate and land use changes on water quantity and quality and (3) to evaluate potential measures to be done in order to achieve a “good ecological status” of the river and its lakes as required by the Water Framework Directive (WFD). The Rhin catchment is a typical highly regulated lowland river basin in Northern Germany. The regulations complicate water quantity and quality modelling in the catchment. The research was done by using the eco-hydrological model SWIM (Soil and Water Integrated Model), which simulates water and nutrient fluxes in soil and vegetation, as well as transport of water and nutrients to and within the river network. The modelling period was from 1981 until 2005. After calibrating the hydrological processes at different gauges within the basin with satisfactory results, water quality (nitrogen and phosphorus) modelling was done taking into account the emissions of different point sources (sewage treatment plants, etc.) and identifying the amount of diffuse pollution caused mainly by agriculture. For suggesting some feasible measures to improve water quality and to reduce diffuse pollution considering possible climate and land use changes, different reasonable scenarios were applied in consultation with the Environmental Agency of Brandenburg (LUA). The study revealed that the amount of water discharge has significant influence on the concentration of nutrients in the river network, and that nitrogen pollution, caused mainly by diffuse sources, could be notably reduced by application of agricultural measures, whereas the pollution by phosphorus could be diminished most effectively by the reduction of point source emissions.

Application of the SIte COmparison Method (SICOM) to assess the potential erosion risk — a basis for the evaluation of spatial equivalence of agri-environmental measures

The paper presents a comparative method (SICOM) to evaluate complex site conditions at different area units as a basis for the estimate of spatial equivalence of agri-environmental measures (AEM). The methodology uses primary site condition data and provides the possibility to compare these data objectively and evaluate different ecological questions. The linking of classified data and spatial equivalence data opens up new possibilities to localize areas of high/low environmental effectiveness (e.g. erosion risk) and to assess the ratio of AEM implementation (acceptance) versus financial input. The use of SICOM is demonstrated for water and wind erosion risk assessment at different scales in the federal state Brandenburg (Germany). The “parcel” aggregation level proves adequate to assess the erosion risk. Larger scales are less useful in the assessment of subsidies policy with regard to erosion risk. A combination of the GIS-moving-window-technique with SICOM establishes the possibility of comparing regions independent of spatial patterns within the landscape.

Liver fluke (Opisthorchiidae) findings in red foxes (Vulpes vulpes) in the eastern part of the Federal State Brandenburg, Germany--a contribution to the epidemiology of opisthorchiidosis.

Parasitological examination of 677 livers from red foxes shot in connection with a rabies control programme were carried out in the eastern districts of the Federal State Brandenburg/Germany in 1996. Of the foxes, 32.5% were positive for opisthorchiid flukes. Metorchis bilis, the most frequently occurring fluke was found in 28.1% of foxes with numbers between 1 and 185. Opisthorchis felineus was found in 6.7% of fox livers. A maximum of 169 specimens was removed from one animal. Pseudamphistomum truncatum was present in only 2 foxes. The percentage of positive foxes in different districts varied between 15.8 and 43.3%. Significant differences in fluke prevalence were found between districts with a high share of surface water compared with a district with a low percentage of surface water. No sex-dependent differences in opisthorchiid prevalence were established.

Seroprevalence of Orthopox Virus Specific Antibodies in Red Foxes (Vulpes vulpes) in the Federal State Brandenburg, Germany

The prevalence of orthopox virus (OPV)-specific antibodies in 1,040 red foxes (Vulpes vulpes) was evaluated on a large scale in the German Federal State Brandenburg. Serum samples were selected from 809 communities within the study area from January 1991 to September 1994 by simple random sampling. Screening was carried out by an indirect enzyme-linked immunosorbent assay (ELISA). Orthopox virus-specific antibodies were found in 162 (16%) of the 1,040 fox sera. Furthermore 154 (15%) sera were considered suspect positive. The specificity of the antibodies detected in ELISA-positive and suspect positive sera was confirmed by Western blotting. Presence of OPV-antibodies occurred in 291 communities. No correlation of OPV-antibodies findings to latitude or characteristic topographical and ecological peculiarities of the study area was found. Although the causative agent is still unknown we believe that orthopox viruses probably have a ubiquitous presence among red foxes.