Features Of Lower Respiratory Infection Research Articles

A study on aetiology and outcomes of viral lower respiratory tract infections in hospitalized children from South India

Introduction: Viral respiratory infection is a common cause of morbidity and mortality in children, especially those less than 5 years old. Objectives: To study the aetiology and seasonal variation of viral lower respiratory tract infection (LRTI) in hospitalized children and to assess the morbidity and mortality. Method: A retrospective cohort study was done on children, aged 1 month to 16 years, admitted in G. Kuppuswamy Naidu Memorial hospital, a tertiary care hospital in Coimbatore, South India. Case records of children hospitalized with features of LRTI, for whom respiratory viral panel was sent, were retrospectively reviewed and were analysed from July 2017 to June 2018. The aetiology of viral infection, age wise distribution, severity of illness and seasonal variation were studied. Multiplex PCR panel was done from either throat swab or nasopharyngeal aspirate in 69 children admitted with a clinician diagnosis of LRTI. Results: Respiratory viruses were identified in 33 (47.8%) of the 69 children. Respiratory syncytial virus (RSV), Influenza viruses A and B, parainfluenza virus and boca virus were the common viruses isolated from hospitalized children with LRTI. RSV and bocavirus were common among children less than 2 years old. RSV infection began in July, peaked during September and October and continued till January. Influenza virus was common among children more than 2 years and occurred between September and March. Conclusions: RSV, Influenza A and B viruses, parainfluenza virus and bocavirus were the common viruses isolated from hospitalized children with LRTI. RSV infection peaked from September to October whilst influenza virus infection peaked from January to March. Sri Lanka Journal of Child Health, 2020; 49(3): 218-222

Observer variation in chest radiography of acute lower respiratory infections in children: a systematic review.

BackgroundKnowledge of the accuracy of chest radiograph findings in acute lower respiratory infection in children is important when making clinical decisions.MethodsI conducted a systematic review of agreement between and within observers in the detection of radiographic features of acute lower respiratory infections in children, and described the quality of the design and reporting of studies, whether included or excluded from the review.Included studies were those of observer variation in the interpretation of radiographic features of lower respiratory infection in children (neonatal nurseries excluded) in which radiographs were read independently and a clinical population was studied. I searched MEDLINE, HealthSTAR and HSRPROJ databases (1966 to 1999), handsearched the reference lists of identified papers and contacted authors of identified studies. I performed the data extraction alone.ResultsTen studies of observer interpretation of radiographic features of lower respiratory infection in children were identified. Seven of the studies satisfied four or more of the seven design and reporting criteria. Six studies met the inclusion criteria for the review. Inter-observer agreement varied with the radiographic feature examined. Kappa statistics ranged from around 0.80 for individual radiographic features to 0.27–0.38 for bacterial vs viral etiology.ConclusionsLittle information was identified on observer agreement on radiographic features of lower respiratory tract infections in children. Agreement varied with the features assessed from "fair" to "very good". Aspects of the quality of the methods and reporting need attention in future studies, particularly the description of criteria for radiographic features.

Radiological features of lower respiratory infection by respiratory syncytial virus in infants and young children

Radiological features of lower respiratory infection by respiratory syncytial virus in infants and young children