As a non-linear phenomenon that varies along with agro-climatic conditions alongside many other factors, Evapotranspiration (ET) process represents a complexity when be assessed especially if there is a data scarcity in the weather data. However, even under such a data scarcity, the accurate estimates of ET values remain necessary for precise irrigation. So, the present study aims to: i) evaluate the performance of six hybrid machine learning (ML) models in estimating the monthly actual ET values under different agro-climatic conditions in China for seven provinces (Shandong, Jiangsu, Zhejiang, Fujian, Jiangxi, Hubei, and Henan), and ii) select the best-developed model based on statistical metrics and reduce errors between predicted and actual ET (AET) values. AET datasets were divided into 78% for model training (from 1958 to 2007) and the remaining was used for testing (from 2008 to 2021). Deep Neural Networks (DNN) was used as a standalone model at first then the stacking method was applied to integrate DNN with data-driven models such as Additive regression (AR), Random Forest (RF), Random Subspace (RSS), M5 Burned Tree (M5P) and Reduced Error Purning Tree (REPTree). Partial Auto-Correlation Function (PACF) was used for selection of the best lags inputs to the developed models. Results have revealed that DNN-based hybrid models held better performance than non-hybrid DNN models, such that the DNN-RF algorithm outperformed others during both training and testing stages, followed by DNN-RSS. This model has acquired the best values of every statistical measure [MAE (10.8, 12.9), RMSE (15.6, 17.4), RAE (31.9%, 41.4%), and RRSE (39.3%, 47.2%)] for training and testing, respectively. In contrast, the DNN model held the worst performance [MAE (14.9, 13.7), RMSE (20.1, 18.2), RAE (43.9%, 43.7%), and RRSE (50.6%, 49.3%)], for training and testing, respectively. Results from the study presented have revealed the capability of DNN-based hybrid models for long-term predictions of the AET values. Moreover, the DNN-RF model has been suggested as the most suitable model to improve future investigation for AET predictions, which could benefit the enhancement of the irrigation process and increase crop yield.