Rudolf Virchow, considered by many the Father of Pathology, established a clear link between human and animal health. From that idea emerged the one medicine concept, which evolved into one health concept many years later. Nevertheless, only recently has there been a renewed interest in the subject, and this for three main reasons: i) The recognition that an extraordinary high percentage of infectious diseases in human were zoonosis; ii) The advances in the knowledge of the genome in man and animals; iii) The huge and rapid scientific progress achieved in recent years in the medical field.