Police violence is a multidimensional issue that requires consideration of the violent events and how these events reflect systemic oppression. Violence and policing practices are influenced by race and ethnicity, place/neighborhood, structural inequality, and racism. We performed an integrated literature review to critically evaluate the current evidence, focusing on the racial composition of communities and neighborhoods and its association with police-involved violence and fatal shootings between 2000 and 2022. We used Scopus and Web of Science to include peer-reviewed articles in English that studied racial/ethnic differences in police-involved violence in the United States between January 2000 and February 2022. We excluded prior systematic reviews, meta-analyses, and articles on drug-related arrests. Using a PRISMA approach from 651 identified articles, we included 37 articles. Our findings showed that racial/ethnic minorities are disproportionately stopped, experience a higher probability of arrest, and are more commonly subjected to police-involved fatal shootings. Victims are more likely to live in neighborhoods with lower income and distressed communities of color, higher poverty ratios, and the highest levels of criminal violence. Citizens reporting of negative interactions with police is strongly associated with race/ethnicity. Maintaining the highest standards of professional practice consistent with the law and protections guaranteed by the Constitution may reduce police violence. In addressing police violence, policymakers not only need to consider the multidisciplinary nature of vulnerability to address the needs of vulnerable populations and create a collaborative environment but also to control police violence. Considering community-based approaches, encouraging training to interact with minority individuals, and adjusting the racial composition of the police officers by the racial composition of communities are other strategies; more importantly, prioritizing strategies to reduce social inequality and structural racism are crucial.