Fat Deposition In Tissue Research Articles

Consistency of feed efficiency ranking and mechanisms associated with inter-animal variation among growing calves.

This study investigated the possible mechanisms for explaining interanimal variation in efficiency of feed utilization in intact male Holstein calves. Additionally, we examined whether the feed efficiency (FE) ranking of calves (n = 26) changed due to age and/or diet quality. Calves were evaluated during three periods (P1, P2, and P3) while fed a high-quality diet (calculated mobilizable energy [ME] of 11.8 MJ/kg DM) during P1 and P3, and a low-quality diet (calculated ME of 7.7 MJ/kg DM) during P2. The study periods were 84, 119, and 127 d, respectively. Initial ages of the calves in P1, P2, and P3 were 7, 11, and 15 mo, respectively, and initial body weight (BW) were 245, 367, and 458 kg, respectively. Individual dry matter intake (DMI), average daily gain (ADG), diet digestibility, and heat production (HP) were measured in all periods. The measured FE indexes were: residual feed intake (RFI), the gain-to-feed ratio (G:F), residual gain (RG), residual gain and intake (RIG), the ratio of HP-to-ME intake (HP/MEI), and residual heat production (RHP). For statistical analysis, animals' performance data in each period, were ranked by RFI, and categorized into high-, medium-, and low-RFI groups (H-RFI, M-RFI, and L-RFI). RFI was not correlated with in vivo digestibility, age, BW, BCS, or ADG in all three periods. The L-RFI group had lowest DMI, MEI, HP, retained energy (RE), and RE/ADG. Chemical analysis of the longissimus dorsi muscle shows that the L-RFI group had a higher percentage of protein and a lower percentage of fat compared to the H-RFI group. We suggested that the main mechanism separating L- from H-RFI calves is the protein-to-fat ratio in the deposited tissues. When efficiency was related to kg/day (DMI and ADG) and not to daily retained energy, the selected efficient L-RFI calves deposited more protein and less fat per daily gain than less efficient H-RFI calves. However, when the significant greater heat increment and maintenance energy requirement of protein compared to fat deposition in tissue were considered, we could not exclude the hypothesis that variation in efficiency is partly explained by efficient energy utilization. The ranking classification of calves to groups according to their RFI efficiency was independent of diet quality and age.

Intrarenal fat deposition does not interfere with the measurement of single-kidney perfusion in obese swine using multi-detector computed tomography

BackgroundAltered vascular structure or function in several diseases may impair renal perfusion. Multi-detector computed tomography (MDCT) is a non-invasive tool to assess single-kidney perfusion and function based on dynamic changes in tissue attenuation during contrast media transit. However, changes in basal tissue attenuation might hamper these assessments, despite background subtraction. Evaluation of iodine concentration using the dual-energy (DECT) MDCT mode allows excluding effects of basal values on dynamic changes in tissue attenuation. We tested whether decreased basal kidney attenuation secondary to intrarenal fat deposition in swine obesity interferes with assessment of renal perfusion using MDCT. MethodsDomestic pigs were fed a standard (lean) or a high-cholesterol/carbohydrate (obese) diet (n = 5 each) for 16 weeks, and both kidneys were then imaged using MDCT/DECT after iodinated contrast injection. DECT images were post-processed to generate iodine and virtual-non-contrast (VNC) datasets, and the MDCT kidney/aorta CT number (following background subtraction) and DECT iodine ratios calculated during the peak vascular phase as surrogates of renal perfusion. Intrarenal fat was subsequently assessed with Oil-Red-O staining. ResultsVNC maps in obese pigs revealed decreased basal cortical attenuation, and histology confirmed increased renal tissue fat deposition. Nevertheless, the kidney/aorta attenuation and iodine ratios remained similar, and unchanged compared to lean pigs. ConclusionsDespite decreased basal attenuation secondary to renal adiposity, background subtraction allows adequate assessment of kidney perfusion in obese pigs using MDCT. These observations support the feasibility of renal perfusion assessment in obese subjects using MDCT.

Relationship between antipsychotic medication, obesity and cognitive functions

AbstractIntroduction: The purpose of this study was to examine whether the combination of atypical and typical antipsychotic medications is related with metabolism and cognitive functions in the same manner and degree as taking medications of one kind only, i.e. atypical or typical.Material and methods: The participants of the study comprised of 91 adults with diagnosed mental illness (F-20-F69). The participants were divided into groups on the basis of the kind of administered medications: T+A (typical and atypical medications), A (atypical medications), T (typical medications), P (antidepressants, sedatives, normothymic/antiepileptic drugs). In the study, Short Test of Mental Status (STMS), Verbal Fluency Test (VFT), Rey Auditory Verbal Learning Test (RAVLT) were used for the purpose of examining cognitive functions.Results: The kind of antipsychotic medications taken by the patients did not differentiate the group in relation to BMI (p<0.13), nor in relation to the level of general cognitive function (p<0.72) or verbal fluency (p<0.34). Both atypical antipsychotic medications and the combination of atypical and typical medications were related to the occurrence of abdominal obesity (p<0.01). An increase in waist circumference decreased an ability of abstract reasoning (p<0.005). When it comes to the body mass index, waist circumference negatively correlated with the delayed memory (p< 0.03, p<0.004).Discussion: Both the combination of atypical and typical antipsychotic medications and atypical medications are associated with the occurrence of abdominal obesity. The deposition of fat tissue in the abdomen negatively correlated with an ability to learn.Conclusions: The future studies might explain the interactions between antipsychotic medications, obesity and cognitive function.

A High Fat Diet during Adolescence in Male Rats Negatively Programs Reproductive and Metabolic Function Which Is Partially Ameliorated by Exercise.

An interaction between obesity, impaired glucose metabolism and sperm function in adults has been observed but it is not known whether exposure to a diet high in fat during the peri-pubertal period can have longstanding programmed effects on reproductive function and gonadal structure. This study examined metabolic and reproductive function in obese rats programmed by exposure to a high fat (HF) diet during adolescence. The effect of physical training (Ex) in ameliorating this phenotype was also assessed. Thirty-day-old male Wistar rats were fed a HF diet (35% lard w/w) for 30 days then subsequently fed a normal fat diet (NF) for a 40-day recovery period. Control animals were fed a NF diet throughout life. At 70 days of life, animals started a low frequency moderate exercise training that lasted 30 days. Control animals remained sedentary (Se). At 100 days of life, biometric, metabolic and reproductive parameters were evaluated. Animals exposed to HF diet showed greater body weight, glucose intolerance, increased fat tissue deposition, reduced VO2max and reduced energy expenditure. Consumption of the HF diet led to an increase in the number of abnormal seminiferous tubule and a reduction in seminiferous epithelium height and seminiferous tubular diameter, which was reversed by moderate exercise. Compared with the NF-Se group, a high fat diet decreased the number of seminiferous tubules in stages VII-VIII and the NF-Ex group showed an increase in stages XI-XIII. HF-Se and NF-Ex animals showed a decreased number of spermatozoa in the cauda epididymis compared with animals from the NF-Se group. Animals exposed to both treatments (HF and Ex) were similar to all the other groups, thus these alterations induced by HF or Ex alone were partially prevented. Physical training reduced fat pad deposition and restored altered reproductive parameters. HF diet consumption during the peri-pubertal period induces long-term changes on metabolism and the reproductive system, but moderate and low frequency physical training is able to recover adipose tissue deposition and reproductive system alterations induced by high fat diet. This study highlights the importance of a balanced diet and continued physical activity during adolescence, with regard to metabolic and reproductive health.

Effects of conjugated linoleic acid on growth, body composition, antioxidant status, lipid metabolism and immunity parameters of juvenile Chu's croaker,Nibea coibor

A-56 days feeding trial was conducted to evaluate the growth performance, feed utilization, biochemical composition, antioxidant status, lipid metabolism and immunity parameters of Chu's croaker Nibea coibor fed diets supplemented with different levels of conjugated linoleic acid (CLA): 0% (control), 0.5%, 1%, 1.5% and 2%. Each diet was randomly assigned to triplicate groups of 25 fish (initial body weight: 12.8 ± 0.1 g) in 15 floating cage. Weight gain (WG) and specific growth rate (SGR) were not significantly affected. 2% of dietary CLA led to significant lower lipid content in both whole body and liver (p < .05). Muscle lipid content was significantly lower in fish fed 1.5% and 2% CLA (p < .05). Saturated fatty acid (SFA) increased while monounsaturated fatty acid (MUFA) decreased with increasing dietary CLA in tissues (p < .05). Increasing CLA significantly promoted hepatic lipase (HL), lipoprotein lipase (LPL), serum lysozyme (LSZ) and immunoglobulin M (IgM) while decreased serum triglyceride (TG) in both liver and serum (p < .05). Liver Superoxide dismutase (SOD), catalase (CAT) and total antioxidant capacity (t-AOC) increased while malondialdehyde (MDA) decreased (p < .05). Our study shown that Chu's croaker can successfully incorporate CLA in tissues up to 2% dietary lipid without growth inhibition, and that CLA increased fish quality due to the increased parameters of lipid metabolism, specific immunity, hepatic antioxidant and CLA accumulation, and the reduction of tissue fat deposition.

Long term health status of children recovering from severe acute malnutrition.

Long term health status of children recovering from severe acute malnutrition.

Failure of lumbar puncture in a patient with spinal epidural lipomatosis: a case report.

We report a case of difficult lumbar puncture due to the inability to obtain adequate cerebrospinal fluid (CSF) in a patient later diagnosed with spinal epidural lipomatosis (SEL). A 76-year-old man with a body mass index (BMI) of 24.1 kg/m2 was scheduled for transurethral resection of a bladder tumor for superficial bladder cancer under spinal anesthesia. The patient had a 3-year history of inhaled steroid use for the management of chronic obstructive pulmonary disease. After placing the patient in the right lateral position, a lumbar puncture was performed via the median approach. However, CSF could not be tapped adequately despite repeated attempts at lumbar puncture, so general anesthetic was administered instead. Subsequently, both anesthesia and surgery proceeded uneventfully. On the first postoperative day, the patient developed mild postdural puncture headache (PDPH), which was treated conservatively. No postoperative neurological complications related to spinal anesthesia were observed. Approximately 2 months after discharge, the patient reported progressive lower back pain and was diagnosed with SEL by magnetic resonance imaging (MRI). A lumbar laminectomy and removal of excessive adipose tissue was performed. After surgery, the patient’s symptoms resolved. The pathogenesis of SEL involves excess fat tissue deposition in the spinal canal, which can lead to obliteration of the spinal subarachnoid space. Therefore, in this patient, the SEL was thought to have caused the inability to obtain adequate CSF during lumbar puncture, and was associated with difficult spinal anesthesia.

English

INTRODUCTION: Pelvic lipomatosis is a rare benign disorder characterized by deposition of mature fat tissue in the pelvic cavity and absence of delimitation by a capsule. Peak incidence of this disease is between 25 to 60 years of age with a staggering male predominance of 10:1. CASE REPORT: A 45 yr. old male presented with epigastric swelling and abdominal pain. Clinically, he was diagnosed with epigastric hernia. Ultrasound showed bladder wall thickening with bilateral hydroureteronephrosis. CT showed bilateral hydrouretronephrosis with pear shaped bladder, non-encapsulated fatty mass surrounding urinary bladder symmetrically, with attenuation similar to that of subcutaneous fat suggesting extensive pelvic lipomatosis. On laparotomy there is a large pelvic lipoma filling the whole of pelvis and bladder was surrounded by fatty tissue all around along with lipoma of the cord. Patient underwent pre peritoneal hernioplasty for ventral hernia and excision of pelvic lipoma and the lipoma of the cord. DISCUSSION: Pelvic lipomatosis is a benign overgrowth of adipose tissue with small amount of inflammatory and fibrotic components found especially in the perivesical and perirectal spaces. The best definitive diagnostic procedure is CT. Various treatments have been attempted, but no single treatment has proved effective to date.

Selective osteogenesis by a synthetic mineral inducing peptide for the treatment of osteoporosis

Mineralization in mammalian cells is accomplished by concerted regulation of protein-based extracellular matrix (ECM) components, such as non-collagenous proteins and collagen fibrils. In this study, we investigated the ability of a collagen-binding motif (CBM) peptide derived from osteopontin to selectively affect osteogenic or adipogenic differentiation in vitro and in vivo. In particular, increased osteogenic differentiation and decreased adipogenic differentiation were observed in human mesenchymal stem cells (hMSCs). Osteocalcin (OCN) protein expression in MC3T3-E1 cells without osteogenic inducers was then investigated following treatment with the CBM peptide. In ovariectomized (OVX) mice, estrogen deficiency induced osteoporosis and increased fat tissue deposition. However, after the CBM peptide or estradiol was injected into the OVX mice for 2 months, the increased serum OCN concentration and alkaline phosphate (ALP) activity were decreased in the estradiol-treated group (OVX-E) and the high-concentration CBM peptide-treated group (OVX-HP). Significant bone loss was also observed in the ovariectomized mice (OVX-PBS). In particular, the bone volume per total volume (BV/TV) and bone mineral density (BMD) were significantly decreased in the OVX mice; however, both of these markers were restored in the OVX-HP group, which also had significantly well-developed bone structure and bone formation. In contrast to the bone structural change, adipose tissue was increased in the OVX-PBS. However, a significant decrease in total fat and subcutaneous fat was observed in the low-concentration CBM peptide-treated group (OVX-LP) and the estradiol-treated group (OVX-E). Taken together, these results suggest that the CBM peptide could be an effective therapeutic agent for osteoporosis due to its selective stimulation of osteogenic differentiation, rather than adipogenesis.

Estimation of residual energy intake and its genetic background during the growing period in pigs

The aims of this study were to (i) compare models estimating residual energy intake (REI) using either lean and fat tissue growth or their proxy traits (average daily gain (ADG) and backfat thickness (BF)); (ii) determine genetic characteristics of REI at different growth stages and the entire test period; and (iii) examine 9 genetic and phenotypic relationships of REI with other production traits. Data from 315 pigs of an F2 generation were used which originated from crossing Pietrain sires with a commercial crossbred dam population. Average daily protein (APD) and lipid deposition (ALD), as measurements of lean and fat tissue growth, were obtained using the deuterium dilution technique on live animals. During growth from 60 to 140kg, REI was estimated using 4 different models for energy intake that included, besides other systematic effects, (1) ADG and BF; (2) APD and ALD; (3) and (4) incorporated the same covariables as the first two models, respectively, but pre-adjusted for systematic effects. Genetic parameters and estimated breeding values were obtained based on univariate animal models using REML analysis. Over the entire growing period, heritabilities of different REI using different models were all estimated at 0.44 and their genetic correlations were at unity. At different growth stages heritabilities for REI were greater ranging from 0.47 to 0.50. Genetic correlations between REI estimates at different stages of growth, obtained using genetic model 4, indicated that REI at 60 to 90kg was non-significantly (P>0.05) associated with REI at 90–120kg (0.32±0.29) and 120–140kg (0.28±0.28), but REI of the latter growth stages showed a significant (P<0.05) moderate genetic correlation (0.58±0.21). REI had favourable genetic correlations with feed conversion ratio (FCR, 0.84±0.13) and total nitrogen excretion (TNE, 0.85±0.11). The results indicate that REI estimated based on models using proxy traits for lean and fat tissue deposition resulted in slightly lower accuracies compared to models fitting APD and ALD, which explained a greater variation of energy intake. There is great potential for improvement of REI due to its large heritability. Genetic selection for REI should consider the stages of growth, because of their differences in genetic background. REI explained a large portion of variance in FCR and TNE, therefore selection for REI is expected to result in, besides improvement of feed efficiency, a substantial reduction in the environmental pollution of pig production.

THU0416 Nutritional Risk Factors of Postmenopausal Osteoporosis

BackgroundAfter menopause the risk of osteoporosis increases significantly caused by subsequent bone loss that can be modified by environmental factors, such as properly balanced diet and physical activity.ObjectivesThe purpose of...

Effects of pregnancy and feeding level on carcass and meat quality traits of Nellore cows

Carcass and meat quality traits of 16 pregnant and 5 non-pregnant cows fed at 1.2 times maintenance and 16 pregnant and 6 non-pregnant fed ad libitum were evaluated. Pregnancy did not affect final body weight (FBW; P=0.0923), cold carcass yield (CCY; P=0.0513), longissimus muscle area (LMA; P=0.8260), rib fat thickness (RFT; P=0.1873) and shear force (WBSF; P=0.9707). A lower FBW (P=0.0028), LMA (P=0.0048) and RFT (P=0.0001) were observed in feed restricted cows. However, no differences were found for CCY (P=0.7243) and WBSF (P=0.0759) among feeding level groups. These data suggests that carcass and meat quality traits are not affected by pregnancy status in Nellore cows. Moreover, although cows experiencing feed restriction did have reduced deposition of subcutaneous fat and lean tissue, there were no major impacts on meat quality traits.

A Piezogenic Papule With Histopathologic Features Simulating Angiomyxolipoma

Piezogenic papules are lesions that occur on the feet and wrists because of the herniation of fat through the dermis. These papules can be painful or completely asymptomatic. Poor compartmentalization of fat occurs because of thinner than normal fibrous trabeculae and contributes to the formation of piezogenic papules. On histological examination, fat is evident extending through the dermis. We report a case of a piezogenic papule simulating angiomyxolipoma on histological examination. The presented case suggests the possibility of an association between herniated fat tissue and mucin deposition with vascular proliferation.

Current recommended levels of dietary lysine in finisher pig diets are sufficient to maximise the response to ractopamine over 28 days but are insufficient in the first 7 days

Dietary ractopamine increases lean tissue deposition and responses increase as dose is increased provided sufficient dietary lysine is supplied. In Australia, diets supplemented with ractopamine (RAC) are formulated with 0.56 g available lysine per MJ digestible energy. The present study was conducted to investigate the interactions between dietary RAC and lysine on growth and carcass characteristics in ad libitum fed (13.8 MJ/kg) boars and gilts. The study involved 108 individually penned pigs at 17 weeks of age (64.1 ± 0.57 kg) in a 2 by 2 by 3 factorial design, with the respective factors being sex (gilt or boar), dietary lysine (low and high, i.e. 0.56 or 0.65 g available lysine/MJ digestible energy, respectively) and dietary RAC (0, 5 or 20 mg/kg) for 28 days. Over the 28-day study duration, both lysine diets containing dietary RAC were sufficient to elicit a response in average daily gain (ADG) (+5.8%, P = 0.026) and carcass weight (3%, P = 0.045), but not in feed efficiency (FE) (P = 0.555). However, over the period of the first 7 days, there were interactions between the effects of RAC and lysine for FE (P = 0.025) and ADG (P = 0.023), with both traits being responsive only to dietary RAC containing the high lysine, which increased FE (+9.1%, P = 0.002) and ADG (+7.2%, P = 0.068). Dietary RAC improved FE in the latter stages of the study, namely Days 15–21 (+5.7%, P = 0.031) and Days 22–28 (+4.9%, P = 0.040). The high RAC diet reduced carcass P2 backfat (–16.5%, P &lt; 0.001) and fat tissue deposition (–6.2%, P = 0.074) and high lysine tended to reduce fat tissue deposition (–13.3%, P = 0.072). A sex by lysine interaction (P = 0.043) was observed for lean tissue deposition at 28 days, such that only the high-lysine diet increased lean deposition in boars (+11%, P &lt; 0.05) but not in gilts. Dietary RAC tended to increase lean deposition (+14.0%, P = 0.067) in the first 14 days; however, only the high RAC diet increased lean deposition (+9.6%, P &lt; 0.05) over 28 days. In conclusion, the current recommended supplementation levels of lysine for commercial gilts and boars fed RAC may limit the response to dietary RAC if the feeding regime is for short durations and boars will not maximise their lean tissue deposition rates.

Pelvic lipomatosis: a case report and literature review

Pelvic lipomatosis is a rare disorder where fat tissue deposition is observed in spaces of the pelvic area, causing extrinsic compression of the bladder, rectum and blood vessels. In the present report, the authors describe the case of a 48-year-old male patient presenting low back pain, dysuria and pollakiuria. Findings at excretory urography, computed tomography and magnetic resonance imaging are described.

Diagnostic accuracy of parotid CT for identifying Sjögren's syndrome

PurposeTo evaluate the diagnostic accuracy of computed tomography (CT) of the parotid gland for Sjögren's syndrome in comparison with conventional X-ray sialography. MethodsCT scans and X-ray sialography were performed in 34 patients with confirmed Sjögren's syndrome and 22 symptomatic controls without the disease. CT data from 57 asymptomatic controls were included for quantitative analysis. The CT findings of heterogeneity, abnormal diffuse fat tissue deposition, diffuse punctate calcification, swelling or atrophy, nodularity or cystic changes of the parotid gland were analyzed by two independent blinded readers. The correlation between CT and X-ray sialography findings was evaluated. Diagnostic performance and receiver operating characteristics curves were calculated. ResultsOn CT, heterogeneity of the parotid gland was seen in 30/31 (reader 1/reader 2) Sjögren's syndrome patients by the two readers (sensitivity 88.2%/91.2%; specificity 100%/90.9%). Abnormal diffuse fat tissue deposition was seen in 28/28 SS patients by the readers (sensitivity 82.3%/82.3%; specificity 100%/90.9%). Diffuse punctate calcification was seen in 10/12 Sjögren's syndrome patients (sensitivity 29.4%/35.2%; specificity 100%/100%). Stagings of CT findings correlate positively with sialography. The areas under the receiver operating characteristics curves were 0.887 (P=0.000) and 0.908 (P=0.000) for the maximum and standard deviation (SD) of the CT value. ConclusionsParotid CT is accurate and reliable in the diagnosis of Sjögren's syndrome. Heterogeneity, abnormal diffuse fat tissue deposition, and diffuse punctate calcification are specific for Sjögren's syndrome. CT attenuation analysis is helpful in diagnosis.

Obesity of Womens in Paleolithicum

Photos and/or copies of a hundred Paleolithic statues were observed. The photos were taken on frontal, lateral and back view. Among the 97 female idols studied, 24 were skinny (mainly young ladies); 15 normal weighed, while more than half of them (51) represents overweighed or very obese females, their breasts was also extremely large. The figurine analysis shows various types of obesity. Fat tissue deposition can be seen on the following places: belly only on 2 figurines; belly + hip on 10 statues; belly + gluteal + hip on 14 idols, belly + hip + gluteal+ femora on 24 statuettes and diffuse obesity on one Venus. Steatopygia could be detected on 7 idols, while these females are not particularly overweight and had reasonably thin waist and legs.

Obesity in the paleolithic era

Photos and/or copies of one hundred Upper Paleolithic (45,000-40,000 to 10,000 BP) statues were studied, the photos having been taken from the frontal, lateral and back view. Among the 97 female idols studied, 24 were skinny (mainly young women), 15 were of normal weight, while more than half of them (51) represented overweight or very obese females whose breasts were also extremely large. The figurine analysis revealed various types of obesity. Increased fat tissue deposition can be seen in the following body parts: belly only in 2 Venus figurines, belly + hip in 10, belly + gluteal + hip in 14, belly + hip + gluteal + femora in 24 and diffuse obesity in one. Steatopygia (derived from the Greek "steato" meaning fat, and "pygia" meaning buttocks and describing excessive fat of the buttocks) was observable in 7 idols, although these females were not particularly overweight and had a reasonably thin waist and legs. Only seven statues were in the state of advanced gravidity (pregnancy). The presence of such a small number of gravidity statuettes challenges the general view concerning Venus idols, namely, that they all represent female fertility.

Composição física da carcaça e características da carne de bovinos de corte terminados em confinamento com diferentes dietas

Avaliou-se o efeito de diferentes dietas sobre as características da carcaça e da carne de bovinos de corte em confinamento: dieta composta por silagem de milho e formulação fixa durante o período de confinamento (SMF); dieta composta por silagem de milho e formulação variável durante o período de confinamento (SMV); dieta composta por silagem de cana-de-açúcar e formulação fixa (SCF); dieta composta por silagem de cana-de-açúcar e formulação variável (SCV); SCV na metade inicial do confinamento e SMV no período final (SCV/SMV). O delineamento experimental foi inteiramente ao acaso, com cinco tratamentos e três repetições. Houve maior deposição de gordura renal-pélvica-inguinal (P=0,03), de gordura subcutânea (P=0,06) e de gordura na carcaça (P=0,06) nas dietas com silagem de milho (6,7kg; 6,2mm e 34,6%) em relação àquelas com silagem de cana-de-açúcar (5,3kg; 4,8mm e 31,7%). Houve maior (P=0,05) rendimento de contrafilé e de miolo de alcatra nas dietas com silagem de milho (10% e 6,9%) em relação às com silagem de cana-de-açúcar (9% e 6,6%). Não houve efeito das dietas sobre rendimento de cortes primários (P&gt;0,1), perdas por cocção (P&gt;0,3) e força de cisalhamento (P&gt;0,1). O ajuste da formulação da dieta e a troca de silagem não influenciaram as características de carcaça e da carne. A utilização de silagem de cana-de-açúcar permitiu carcaças com acabamento satisfatório

Behavior of Visfatin in Nonobese Women Undergoing Liposuction: A Pilot Study

The adipocyte has recently begun to be considered not just as a fat deposition tissue, but also as a true endocrine organ. Adipose tissue produces a wide variety of adipocytokines, of which visfatin is one. Since visfatin has recently been described as a mimic of insulin action, the authors evaluate visfatin behavior in women undergoing liposuction. Nineteen nonobese women underwent liposuction of abdominal fat. Patient visfatin levels and a lipid profile were obtained preoperatively, and the results were compared with the results of the same tests immediately postoperatively and one month postoperatively. The mean age of the 19 study participants was 33 years; mean body mass index was 24.7±2.2 kg/m2. The amount of subcutaneous fat obtained was an average of 4468±1403 kg. Visfatin increased from 51.8±24.4 ng/mL preoperatively to 76.3±39.8 ng/mL (P=.02). Pre- and postoperative lipid profiles reflected, respectively, the following: total cholesterol, 159.1±37.1 vs 164.6±31.7 mg/dL (P=.420); high-density cholesterol, 41.4±8.6 vs 39.3±9.9 mg/dL (P=.421); low-density cholesterol, 97.1±25.4 vs 100±19.2 mg/dL (P=.507); and triglycerides, 92.3±57.1 vs 126.3±72.5 mg/dL (P=.058). Visfatin levels were shown to increase after liposuction of subcutaneous fat. The authors conclude that this adipocyte may play an important role as a regulatory reciprocal mechanism.