Fast Regime Research Articles

Retraction: Dietary patterns in adults following the Christian Orthodox fasting regime in Greece

Retraction: Dietary patterns in adults following the Christian Orthodox fasting regime in Greece

Investigating ocean circulation dynamics through data assimilation: A mathematical study using the Stommel box model with rapid oscillatory forcings.

We investigate ocean circulation changes through the lens of data assimilation using a reduced-order model. Our primary interest lies in the Stommel box model, which reveals itself to be one of the most practicable models that has the ability of reproducing the meridional overturning circulation. The Stommel box model has at most two regimes: TH (temperature driven circulation with sinking near the north pole) and SA (salinity driven with sinking near the equator). Currently, the meridional overturning is in the TH regime. Using box-averaged Met Office EN4 ocean temperature and salinity data, our goal is to provide a probability that a future regime change occurs and establish how this probability depends on the uncertainties in initial conditions, parameters, and forcings. We will achieve this using data assimilation tools and DAPPER within the Stommel box model with fast oscillatory regimes.

Can temperature be a low-cost tracer for modelling water age distributions in a karst catchment?

To investigate the feasibility of using temperature for tracking rainfall-runoff processes in karst catchments, this study developed a tracer-aided conceptual model using temperature as a tracer by coupling water and heat transport processes at the catchment scale. The model was calibrated and validated using hourly hydrometeorological and temperature data from a 1.25 km2 karst catchment in south-western China. The results showed that the model was able to capture the water flux and temperature dynamics of different landscape units in the karst catchment. Utilizing this framework, the model delineated the flux age distribution within different landscape units, as well as the overall water transit times through the catchment. The average flux ages were determined to be approximately 80 days for the hillslope unit, 452 days for the slow flow system, and 260 days for the fast flow regime within the depression areas. These estimations align broadly with those acquired using stable isotopes as tracers. Comparative analysis revealed that the flux age distributions derived from both temperature and isotopic tracers exhibited analogous patterns at the catchment outlet and across the hillslope compartments. However, the simulations based on temperature hinted at a heightened proportion of exceedingly young and decidedly old water in the outflow, alluding to a potential overestimation of these extreme age classes by the temperature-tracer model. From the temperature-simulated transit time distribution, about 31 % of the precipitation entering during the study period have left the catchment within 3 years, and a notable proportion of rain water was either stored in the aquifer or lost through evapotranspiration. The general characteristics of the transit time distribution simulated using temperature was similar with that simulated using isotopes, though a higher proportion of precipitation being drained by fast flows was inferred from the transit time distribution simulated using temperature. Collectively, our study demonstrated that temperature can serve as a cost-effective tracer for modelling of water age distributions and associated hydrological processes in karst catchments.

Observation of giant group index in a multi-level 85Rb atomic medium at room temperature.

We report an experimental measurement of giant group index in the 85Rb atomic medium at room temperature via a four-level V-type scheme on the D2 line. Our experiment uses co-propagation configuration of probe and coupling lasers through an atomic sample. In this configuration, three sharp EIT windows with significant transparency depths are observed on the probe absorption spectrum. By establishing a Mach-Zehnder interferometer, we measure the dispersive curve and hence obtain the group index curve with three enhanced positive peaks at the locations of the EIT windows, interspersed with negative peaks. The amplitude of the group index curve is increased as the temperature decreases and is decreased as the temperature increases. We estimate from our experimental results the good values of the group index to be ng = 5.8 × 104 (slow light regime) and ng = -4.0 × 104 (fast light regime). We also show that the experimental measurements are in good agreement with the theoretical results.

The hyperbolic umbilic singularity in fast-slow systems

Fast-slow systems with three slow variables and gradient structure in the fast variables have, generically, hyperbolic umbilic, elliptic umbilic or swallowtail singularities. In this article we provide a detailed local analysis of a fast-slow system near a hyperbolic umbilic singularity. In particular, we show that under some appropriate non-degeneracy conditions on the slow flow, the attracting slow manifolds jump onto the fast regime and fan out as they cross the hyperbolic umbilic singularity. The analysis is based on the blow-up technique, in which the hyperbolic umbilic point is blown up to a 5-dimensional sphere. Moreover, the reduced slow flow is also blown up and embedded into the blown-up fast formulation. Further, we describe how our analysis is related to classical theories such as catastrophe theory and constrained differential equations.

The Structural and Orbital Effects of Active Galactic Nuclei Feedback on SMBH Binaries Embedded in Gaseous Circumbinary Disks

Using subparsec-scale-resolution radiation+hydrodynamical adaptive mesh refinement simulations deployed with the RAMSES code, we study the dynamics of supermassive black hole (SMBH) binaries embedded in gaseous nuclear circumbinary disks, where we investigate the effects of active galactic nucleus feedback on the SMBH binaries' migration behavior and disk structure. The radiative feedback effects are modeled by injecting photons that interact with the gas, through the adoption of a grid of BH emission spectra. We run simulations with initial conditions that lead by pure gravity plus hydrodynamics both to the formation of a low-density tidal cavity and to systems where gas–viscous diffusion is efficient enough to maintain a sizable gas reservoir surrounding the binary. For gap-forming binaries we find that orbital evolution is unchanged with the inclusion of feedback, but ionizing radiation photoevaporates gas that is at the outer edge of the low-density region. For non-gap-forming systems we find that when feedback is included a strong initial disruption of the circumbinary disk is followed by an eventual stabilization of the medium that can usher a return to a fast binary migration regime. All of this is possible as a result of how our simulations capture the ionization states of the nuclear disk region and how this affects the coupling efficiency decrease with respect to the radiative feedback.

A two-phase model of galaxy formation – II. The size–mass relation of dynamically hot galaxies

ABSTRACT In Paper-I, we developed a two-phase model to connect dynamically hot galaxies (such as ellipticals and bulges) with the formation of self-gravitating gas clouds (SGCs) associated with the fast assembly of dark matter haloes. Here, we explore the implications of the model for the size–stellar mass relation of dynamically hot galaxies. Star-forming sub-clouds resulting from the fragmentation of the turbulent SGC inherit its spatial structure and dynamical hotness, producing a ‘homologous’ relation, $r_{\rm f}\approx \, 100\, r_{\rm bulge}$, between the size of a dynamically hot galaxy ($r_{\rm bulge}$) and that of its host halo assembled in the fast regime ($r_{\rm f}$), independent of redshift and halo mass. This relation is preserved by the ‘dry’ expansion driven by dynamical heating when a galaxy becomes gas-poor due to inefficient cooling, and is frozen due to the stop of bulge growth during the slow assembly regime of the halo. The size–stellar mass relation is thus a simple combination of the galaxy–halo homology and the non-linear stellar mass–halo mass relation. Using a set of halo assembly histories, we reproduce all properties in the observed size–mass relation of dynamically hot galaxies, including the flattening in the low-mass end and the upturn in the massive end. The prediction matches observational data currently available to $z \approx 4$, and can be tested in the future at higher z. Our results indicate that the sizes of dynamically hot galaxies are produced by the dissipation and collapse of gas in haloes to establish SGCs in which stars form.

Travelling waves in a minimal go-or-grow model of cell invasion

We consider a minimal go-or-grow model of cell invasion, whereby cells can either proliferate, following logistic growth, or move, via linear diffusion, and phenotypic switching between these two states is density-dependent. Formal analysis in the fast switching regime shows that the total cell density in the two-population go-or-grow model can be described in terms of a single reaction–diffusion equation with density-dependent diffusion and proliferation. Using the connection to single-population models, we study travelling wave solutions, showing that the wave speed in the go-or-grow model is always bounded by the wave speed corresponding to the well-known Fisher–KPP equation.

Solid-state NMR backbone chemical shift assignments of α-synuclein amyloid fibrils at fast MAS regime.

The α-synuclein (α-syn) amyloid fibrils are involved in various neurogenerative diseases. Solid-state NMR (ssNMR) has been showed as a powerful tool to study α-syn aggregates. Here, we report the 1H, 13C and 15N back-bone chemical shifts of a new α-syn polymorph obtained using proton-detected ssNMR spectroscopy under fast (95kHz) magic-angle spinning conditions. The manual chemical shift assignments were cross-validated using FLYA algorithm. The secondary structural elements of α-syn fibrils were calculated using 13C chemical shift differences and TALOS software.

Fluid motion in a cavity driven by a four-sided moving lid with uniform velocity

This work investigates the mixing phenomenon within rectangular cavities of various aspect ratios, all four sides driven at the same speed in a clockwise direction. For the creeping flow regime, an analytical solution using real eigenfunction expansion is derived. Inertia’s influence under higher flow rates is then numerically simulated using a built-in finite element technique in the Mathematica software. For a square cavity, the inherent structural symmetry is combined with the dynamical symmetry of the velocity field. However, changing the aspect ratio disrupts this symmetry in the horizontal and vertical velocities. Interestingly, unlike other wall-driven cavity flows found in the literature, the recirculating zone in this system forms a single vortex without any corner eddies at any Reynolds number. This unique feature offers tremendous potential for controlling the mixing process. In the highly viscous regime, the pressure field is dominated by odd functions in both x and y. As inertia increases, even functions in x and y become more significant, causing the velocities near the moving lids to overshoot their steady-state values. The extent of this overshoot depends on the cavity’s aspect ratio, and such a fast mixing regime could be valuable for industrial fluid mixing applications.

Presentation of microstructural diffusion components by color schemes in abdominal organs.

Development of a color scheme representation to facilitate the interpretation of tri-exponential DWI data from abdominal organs, where multi-exponential behavior is more pronounced. Multi-exponential analysis of DWI data provides information about the microstructure of the tissue under study. The tri-exponential signal analysis generates numerous parameter images that are difficult to analyze individually. Summarized color images can simplify at-a-glance analysis. A color scheme was developed in which the slow, intermediate, and fast diffusion components were each assigned to a different red, green, and blue color channel. To improve the appearance of the image, histogram equalization, gamma correction, and white balance were used, and the processing parameters were adjusted. Examples of the resulting color maps of the diffusion fractions of healthy and pathological kidney and prostate are shown. The color maps obtained by the presented method show the merged information of the slow, intermediate, and fast diffusion components in a single view. A differentiation of the different fractions becomes clearly visible. Fast diffusion regimes, such as in the renal hilus, can be clearly distinguished from slow fractions, such as in dense tumor tissue. Combining the diffusion information from tri-exponential DWI analysis into a single color image allows for simplified interpretation of the diffusion fractions. In the future, such color images may provide additional information about the microstructural nature of the tissue under study.

The asymptotic solution of near-limit chain-branching premixed flames with the Zel’dovich–Liñán two-step mechanism in the linear and fast recombination regime

Near-limit characteristics of chain-branching premixed flames is investigated numerically and asymptotically by employing the Zel’dovich–Liñán two-step mechanism with linear and (sufficiently) fast recombination, for which both chain-branching and -recombination steps take place in a thin reactive layer of O(β−1), with β being the chain-branching Zel’dovich number. The numerical and asymptotic results reveal that the rate-ratio eigenvalue r between the chain branching and recombination steps approaches a minimum critical value of rmin→e as the chain-recombination step becomes infinitely fast. The existence of the finite asymptotic value of r=e indicates that no steadily propagating flame solution can be found for fuel concentrations lower than its critical value, corresponding to the criticality of r=e, thereby explaining the (lean) flammability limit. This intrinsic flammability characteristics with linear recombination is the most outstanding contrast to the quadratic recombination counterpart, for which flammability is achieved only with external heat loss added to the model.Novelty and significance statementNear-limit combustion characteristics of chain-branching flames is investigated numerically and asymptotically by employing the Zel’dovich–Linan two-step chemical kinetics with linear and fast recombination. This work demonstrates that the rate-ratio eigenvalue between the chain-branching and -recombination steps asymptotically approaches a critical minimum value, corresponding to the flammability limit. The existence of flammability limit with the linear recombination is found to be the most significant contrast to the quadratic recombination model, which is incapable of predicting flammability limit. By this study, a formal asymptotic procedure, by which the crossover temperature and lean flammability limit condition can be determined without assuming a steady-state approximation of intermediate species, is established and can be applied to analyze flame structures with multi-step reduced mechanisms.

The Effect of Lysozyme on the Aggregation and Charging of Oxidized Carbon Nanohorn (CNHox) in Aqueous Solution

To clarify the effect of proteins on the charging and aggregation–dispersion characteristics of oxidized carbon nanohorn (CNHox), we measured the electrophoretic mobility and stability ratios as a function of concentrations of a model protein, lysozyme (LSZ), and KCl. The zeta potential from the electrophoretic mobility of CNHox was neutralized and reversed by the addition of oppositely charged LSZ. Electrical and hydrophobic interactions between CNHox and LSZ can be attributed to the adsorption and charge reversal of CNHox. The stability ratio of CNHox in the presence or absence of LSZ showed Derjaguin–Landau and Verwey–Overbeek (DLVO) theory-like behavior. That is, the slow aggregation regime, fast aggregation regime, and critical coagulation concentration (CCC) were identified. At the isoelectric point, only the fast aggregation regime was shown. The existence of patch-charge attraction due to the charge heterogeneity on the surface was inferred to have happened due to the enhanced aggregation of CNHox at high LSZ dosage and low electrolyte concentration. The relationship between critical coagulation ionic strength and surface charge density at low LSZ dosage showed that the aggregation of CNHox is in line with the DLVO theory. An obvious decrement in the Hamaker constant at high LSZ dosage can probably be found due to an increased interaction of LSZ-covered parts.

A closer examination of the nature of atomic motion in the interfacial region of crystals upon approaching melting.

Although crystalline materials are often conceptualized as involving a static lattice configuration of particles, it has recently become appreciated that string-like collective particle exchange motion is a ubiquitous and physically important phenomenon in both the melting and interfacial dynamics of crystals. This type of collective motion has been evidenced in melting since early simulations of hard disc melting by Alder et al. [Phys. Rev. Lett. 11(6), 241-243 (1963)], but a general understanding of its origin, along with its impact on melting and the dynamics of crystalline materials, has been rather slow to develop. We explore this phenomenon further by focusing on the interfacial dynamics of a model crystalline Cu material using molecular dynamics simulations where we emphasize the geometrical nature and spatial extent of the atomic trajectories over the timescale that they are caged, and we also quantify string-like collective motion on the timescale of the fast β-relaxation time, τf, i.e., "stringlets." Direct visualization of the atomic trajectories in their cages over the timescale over which the cage persists indicates that they become progressively more anisotropic upon approaching the melting temperature Tm. The stringlets, dominating the large amplitude atomic motion in the fast dynamics regime, are largely localized to the crystal interfacial region and correspond to "excess" modes in the density of states that give rise to a "boson peak." Moreover, interstitial point defects occur in direct association with the stringlets, demonstrating a link between classical defect models of melting and more recent studies of melting emphasizing the role of this kind of collective motion.

Coupled kinetic and hydrodynamic model for a carbonator reactor of calcium looping process: Sulfur dioxide effect

The application of the calcium looping (CaL) process for CO2 capture has gained recognition as a highly efficient technology in mitigating greenhouse gases emission. In this study, by considering the characteristics of the adsorbent and the hydrodynamics of the fluidized bed in the fast fluidization regime, a fractal-like random pore kinetic model and a 1D hydrodynamic model were combined together. In order to validate the kinetic model, experimental carbonation data obtained from a lab-scale fluidized bed reactor under realistic operational condition and in the absence/presence of SO2 gas were used. The results demonstrated a satisfactory agreement between the model and experimental data, as indicated by the maximum absolute error of 1.23% and 1.78% in the absence and presence of SO2, respectively. Based on sensitivity analysis, the efficiency of the carbonator reactor was found to be predominantly affected by the solid inventory in the bed and the gas inlet velocity. Also, the results of this analysis indicate that in the presence of SO2, a higher make-up flow rate leads to a more pronounced enhancement in the efficiency of the carbonator reactor, as compared to the absence of SO2 in the reaction environment. Results of modelling indicated that the presence of SO2 necessitated a 36.5-fold increase in the minimum-required make-up flow to attain comparable efficiency obtained in the condition of the absence of SO2. Furthermore, the results of modelling as a function of number of cycles demonstrated a substantial decline in the efficiency of the carbonator reactor, which in the absence of SO2, the efficiency decreased from 68.13% to 18.81%, while in the presence of SO2, it decreased from 45.53% to 4.75% over 100 sequential cycles.

The ion cyclotron parametric instabilities and the anomalous heating of ions in the scrape-off layer of tokamak plasma in the high harmonic fast wave heating regime

The electrostatic parametric instabilities of a plasma, driven by the high harmonic fast wave (HHFW) with frequency at ion cyclotron (IC) harmonics of order 30–50 are investigated numerically. The derived numerical results are consistent with parametric decay of HHFW into the high harmonic IC (Bernstein) wave and an unobserved IC quasimode under conditions of the negligible small electron Landau damping. The detected instability develops in the finite interval of the HHFW wavelength along the toroidal magnetic field. The development of this ion kinetic quasimode decay instability is accompanied by the anomalous anisotropic heating of ions, resulted from the interaction of ions with IC parametric turbulence. It was found that the anomalous heating rate of ions across the magnetic field is much larger than the heating rate of ions along the magnetic field. The anisotropic heating of the scrape-off layer ions was observed on the National Spherical Torus Experiment experiments with HHFW heating and current drive at IC harmonics of order 10 [G. Taylor et al. Phys. Plasmas 17, 056114 (2010), and J. Hosea et al. Phys. Plasmas 15, 056104 (2008)]. The derived results predict that these experimental results will be reproduced qualitatively in the experiments with HHFW heating and current drive using HHFW at IC harmonics of order 30–50.

Acoustic streaming: insights across Reynolds numbers

When a fluid system is subjected to an acoustic wave (or another periodic actuation), the response of the fluid is not purely periodic, but is rather characterized by the combination of a periodic flow and a steady Stokes drift component, where the former is, in many cases, an acoustic wave and the latter is commonly referred to as acoustic streaming. Classical theories of acoustic streaming have focused on slow acoustic streaming, where the periodic flow is the leading-order flow, and is insensitive to the steady flow component which appears as a small correction and is characterized by a small hydrodynamic Reynolds number. In contrast, Dubrovski et al. (J. Fluid Mech. vol. 975, 2023, A4) tackle the fast acoustic streaming regime – conceived by Zarembo (Acoustic streaming. In High-Intensity Ultrasonic Fields, 1971, pp. 135–199. Springer) approximately fifty years ago – where both the periodic and steady flow components are of a similar order of magnitude such that the periodic flow both supports and is simultaneously impacted by the steady flow. They present a novel theoretical framework that accounts for the convection of momentum both within and between the periodic and steady flow to extend slow-streaming equations to the case of steady flow with arbitrary hydrodynamic Reynolds number. They leverage a scaling analysis of the resulting system of equations and a case study to demonstrate the compatibility of their equations with slow streaming theories and highlight the distinctive features of fast streaming.

Preferential ordering of incommensurate-length guest particles in a smectic host.

Using density functional theory, we study the preferential ordering of rod-like guest particles immersed in a smectic host fluid. Within a model of perfectly aligned rods and assuming that the guest particles do not perturb the smectic host fluid, simple excluded-volume arguments explain that guest particles that are comparable in length to the host particles order in phase with the smectic host density layering, whereas guest particles that are considerably shorter or longer order in antiphase. The corresponding free-energy minima are separated by energetic barriers on the order of the thermal energy kBT, suggesting that guest particles undergo hopping-type diffusion between adjacent smectic layers. Upon introducing a slight orientational mismatch between the guest particles and the perfectly aligned smectic host, an additional, smaller free-energy barrier emerges for a range of intermediate guest-to-host length ratios, which splits the free-energy minimum into two. Guest particles in this range occupy positions intermediate between in-phase ordering and in-antiphase ordering. Finally, we use Kramers' theory to identify slow, fast, and intermediate diffusive regimes for the guest particles as a function of their length. Our model is in qualitative agreement with experiment and simulation and provides an alternative, complementary explanation in terms of a free-energy landscape for the intermediate diffusive regime, which was previously hypothesized to result from temporary caging effects [M. Chiappini, E. Grelet, and M. Dijkstra, Phys. Rev. Lett. 124, 087801 (2020)]. We argue that our simple model of aligned rods captures the salient features of incommensurate-length guest particles in a smectic host if a slight orientational mismatch is introduced.

Comparative Study on Adaptive Bayesian Optimization for Batch Cooling Crystallization for Slow and Fast Kinetic Regimes.

Crystallization kinetic parameter estimation is important for the classification, design, and scale-up of pharmaceutical manufacturing processes. This study investigates the impact of supersaturation and temperature on the induction time, nucleation rate, and growth rate for the compounds lamivudine (slow kinetics) and aspirin (fast kinetics). Adaptive Bayesian optimization (AdBO) has been used to predict experimental conditions that achieve target crystallization kinetic values for each of these parameters of interest. The use of AdBO to guide the choice of the experimental conditions reduced material usage up to 5-fold when compared to a more traditional statistical design of experiments (DoE) approach. The reduction in material usage demonstrates the potential of AdBO to accelerate process development as well as contribute to Net-Zero and green chemistry strategies. Implementation of AdBO can lead to reduced experimental effort and increase efficiency in pharmaceutical crystallization process development. The integration of AdBO into the experimental development workflows for crystallization development and kinetic experiments offers a promising avenue for advancing the field of autonomous data collection exploiting digital technologies and the development of sustainable chemical processes.

Sustainability of Growth Performance, Water Quality, and Productivity of Nile Tilapia-Spinach Affected by Feeding and Fasting Regimes in Nutrient Film Technique-Based Aquaponics

Aquaponic systems offer an innovative approach to sustainable agriculture, where the interplay between fish and plant cultivation can be optimized. The choice of feeding and fasting schedules plays a crucial role in system efficiency and overall productivity. This study aims to investigate the impacts of various feeding and fasting schedules on water quality, and the growth performance of Nile tilapia, Oreochromis niloticus fingerlings, and spinach productivity in an aquaponic system based on the nutrient film technique (NFT). O. niloticus fingerlings with an initial weight of 13.47 ± 0.14 g were randomly stocked at a density of 6 kg/m3, and spinach plants (Spinacia oleracea) were included. The study employed a completely randomized block design with five replications. Various water quality parameters were monitored, and the effects of different feeding/fasting schedules on fish and spinach were assessed. The data revealed significant differences (p < 0.05) in water quality parameters, all of which remained within acceptable ranges for aquaponic systems. The one-day feeding/one-day fasting treatment resulted in reduced final body weight, weight gain percentage, and specific growth rate, compared to other treatment groups (p < 0.05). Higher levels of glucose and plasma cortisol were observed in this treatment. Economic efficiency was highest in the daily feeding treatment (40.05%), with no statistical difference (p > 0.05) observed in the group subjected to three-day feeding/one-day fasting (39.03%). Spinach yield varied significantly between treatments (p < 0.05), with the daily feeding treatment recording the highest yield (2.78 kg/m2) and the one-day feeding/one-day fasting cycle having the lowest yield (1.57 kg/m2). The findings suggest that the three-day feeding/one-day fasting regime in an NFT-based aquaponic system results in efficient nutrient utilization, higher productivity, and profitability for Nile tilapia. Additionally, this approach supports marketable biomass production for spinach. Different feeding and fasting schedules have distinct effects on water quality, fish growth, and spinach productivity in aquaponic systems. The three-day feeding/one-day fasting schedule emerges as an effective strategy for optimizing resource utilization and increasing overall productivity.