Irrigation plays a vital role in many agricultural crop production regions. Drainage water recycling (DWR) is a popular irrigation water management system that collects excess water drained from cropland fields and stores it in on-site reservoirs for reuse. The efficacy of these systems varies by location, climate, irrigation frequency, and crop demands. Simulating this system would be beneficial for assessing the impact of water and land management practices on agriculture and natural resources. This study presents the development of computational algorithms for DWR simulation with the Agricultural Policy Environmental eXtender (APEX) model, along with the results for 39 testing sites where both reservoir and drainage systems are adopted. Simulating a DWR system with the revised reservoir module, the APEX model simulates irrigation water reuse ranging between 29% and 93%; sediment reduction of around 66%; nitrogen loss reduction of 23% and 73% for the mineral and organic forms, respectively; and phosphorus loss reduction of 22% and 79% for the soluble and sediment-transported forms, respectively. In conclusion, the results provided by the APEX model for sediment loss reduction align with field data, but discrepancies for nitrogen and phosphorus losses emerged from this test.