Climate change affects many areas of human lives, including agriculture. Interestingly, agriculture contributes to climate change, necessitating climate smart approaches to ensure a win-win situation; wherein agricultural production is sustainable and meets current and future needs. Climate smart agriculture is a collection of agricultural practices that increase productivity, adaptation, and mitigation of climate change contribution to agriculture. While many global regions depend on agriculture directly and indirectly, the sub-Saharan Africa region is directly dependent on agriculture. Existing “climate smart” activities in this region must be better defined and strengthened to achieve its objectives – increasing agricultural productivity, adapting agricultural systems, and mitigating emissions from agricultural activities. Among these climate smart activities are the significance of soil microorganisms, particularly arbuscular mycorrhizal fungi in sustainable agricultural systems, where they provide limited plant nutrients, control pests and diseases, aid drought adaptation, improve soil structure, reduce nutrient loss during leaching, leading to sustainable soil management.