Annual patterns in climate parameters were studied to evaluate how these influence the quality of reference evapotranspiration (ETo) estimates obtained from the Hargreaves-Samani (HS) equation, since the method only uses the measured temperature directly. The work evaluates how these patterns can be used to improve the HS ETo estimates. Ten-year moving averages from a set of California Irrigation Management Information System (CIMIS) stations were used to evaluate the relationships between solar radiation (Rs), temperature (T) and ETo. The results indicate that T treads behind solar radiation and its value peaks some 25 days later. Thus, the main irrigation season in the Mediterranean climate (1 May–30 September) can be divided into three phases: increasing Rs and T; decreasing Rs with increasing T; and decreasing Rs and T. Non-univocal annual cycles were observed between Rs and T, ETo and Rs, and ETo and T. These annual patterns result in important seasonal changes in the ratio between the HS and Penman-Monteith (FAO PM) ETo estimates. The changes are particularly important during the irrigation season, where the FAO PM initially calculates greater ETo values than the HS methodology, and from the end of May to early September, where the HS equation overestimates the ETo values (by 17 mm, or 3%). These patterns obtained from 2000–2009 data were used to calibrate and improve HS ETo estimates at new sites for the 2010–2011 period. Calibration based on the proposed seasonal region-wide FAO PM/HS ETo ratios improved both the bias (decreased from 0.40 to 0.36 mm d-1) and r2 (increased from 0.67 to 0.87) of the ETo estimates for the irrigation season. The proposed methodology can be easily applied to other regions, even when the existing weather stations are sparse.Editor Z.W. Kundzewicz