We experimentally demonstrate Fano resonance in a metamaterial composed of an asymmetric ferroelectric wire pair. By assembling two parallel ceramic wires of different lengths, sharp Fano-type transmission spectra emerge as a result of interference between the quadrupole and dipole modes. A rapid increase in group delay is observed as a result of a steep variation in transmission phase. The location of the Fano resonance peak depends on the wire separation and degree of asymmetry. Furthermore, Fano resonance can be thermally modulated from 9.8 GHz to 10.5 GHz as the ambient temperature varies from 10 °C to 50 °C, as a consequence of the temperature dependence of the permittivity of the ceramic material.