Familial Heritability Research Articles

Clinical characteristics and genetic analysis of a case of a patient with familial hereditary breast cancer: a case report

BackgroundBreast cancer has emerged as the foremost cause of female mortality worldwide, with triple negative breast cancer accounting for approximately 10–15% of all breast cancer cases. The triple negative breast cancer family has obvious familial heritability, but no potential pathogenic variation was found in BRCA1/2.Case presentationThe patient was a 56-year-old woman of Han ethnicity. The clinical characteristics of this patient with breast cancer were summarized, peripheral blood of one normal female and two patients with breast cancer in this family was collected, DNA was extracted, and the potential pathogenic variation was analyzed by whole exome sequencing. The normal female and two patients with breast cancer in this family shared a maternal grandmother. The proband’s right breast mass was punctured, and the biopsy showed invasive carcinoma of the right breast, grade II–III, with necrosis. No mutation was found in BRCA1/2 gene test; immunohistochemical of surgical specimens showed triple negative breast cancer. Three mutation types and 17 gene mutation sites were detected through bioinformatics prediction analysis on the basis of co-segregation of genotype and phenotype within the family and whole exome sequencing results. Combined with the Cancer Genome Atlas database comprehensive analysis, the MT1E c.G107A (p.C36Y) mutation may be a potential pathogenic site.ConclusionsThrough whole exome sequencing, we identified a total of 17 potential pathogenic mutation loci, none of which have been reported thus far. Therefore, our work expanded the gene mutation spectrum of familial hereditary triple negative breast cancer, which can provide more basis for family genetic counseling.

Trunk distortion weakens the tree productivity revealed by half-sib progeny determination of Pinus yunnanensis

Twisted trunks are not uncommon in trees, but their effects on tree growth are still unclear. Among coniferous tree species, the phenomenon of trunk distortion is more prominent in Pinus yunnanensis. To expand the germplasm of genetic resources, we selected families with excellent phenotypic traits to provide material for advanced generation breeding. The progeny test containing 93 superior families (3240 trees) was used as the research material. Phenotypic measurements and estimated genetic parameters (family heritability, realistic gain and genetic gain) were performed at 9, 15, and 18 years of age, respectively. The genetic evaluation yielded the following results (1) The intra-family variance component of plant height (PH) was greater than that of the inter-family, while the inter-family variance components of other traits (diameter at breast height (DBH), crown diameter (CD), height under branches (HUB), degree of stem-straightness (DS)) were greater than that of the intra-family, indicating that there was abundant variation among families and potential for selection. (2) At half rotation period (18 years old), there was a significant correlation among the traits. The proportion of trees with twisted trunks (level 1–3 straightness) reached 48%. The DS significantly affected growth traits, among which PH and DBH were the most affected. The volume loss rate caused by twisted trunk was 18.06-56.75%, implying that trunk distortion could not be completely eliminated after an artificial selection. (3) The influence of tree shape, crown width, and trunk on volume increased, and the early-late correlation between PH, DBH and volume was extremely significant. The range of phenotypic coefficient of variation, genetic variation coefficient and family heritability of growth traits (PH, DBH, and volume) were 44.29-127.13%, 22.88-60.87%, and 0.79–0.83, respectively. (4) A total of 21 superior families were selected by the method of membership function combined with independent selection. Compared with the mid-term selection (18 years old), the accuracy of early selection (9 years old) reached 77.5%. The selected families’ genetic gain and realistic gain range were 5.79-19.82% and 7.12-24.27%, respectively. This study can provide some useful reference for the breeding of coniferous species.

Estimation of genetic parameter for growth of one year old Swietenia macrophylla King. progeny trial in Trenggalek, East Java

After being introduced to Indonesia, Swietenia macrophylla King. has since been widely planted for community and plantation forests in several locations. This study was carried out to ascertain the growth variation, heritability, and genetic correlation of the 1-year-old S. macrophylla progeny trial in Trenggalek, East Java. This progeny trial was designed of incomplete block design (IBD), and the plant materials are 50 families from Banjar-Ciamis, Samigaluh-Kulonprogo, Dlingo-Bantul, Bondowoso-East Java, and Lombok-West Nusa Tenggara. Three individuals were planted in line tree plot for each family, repeated 6 times with a spacing of 4m x 2m. According to the findings, the Bondowoso land race had the best growth with a height and stem diameter of 0.81 m and 1.12 cm, respectively. Families’ varying heights were divided into 14 groups, and the stem diameter was divided into 13 groups. The stem diameter has individual and family heritabilities of 0.23 (moderate) and 0.53 (moderate), respectively, whereas the height’s individual and family heritabilities are 0.39 (high) and 0.65 (high), respectively. Height and stem diameter showed a positive and strong of genetic correlation (0.90).

Growth diversity, heritability, and genetic correlation of 2-year-old of manglid (Manglietia glauca Bl.) progeny test in Candiroto, Temanggung, Central Java

Manglid, an Indonesian flora, is highly sought after due to its high public interest in planting it. It is necessary to develop superior seed sources to increase the plant’s productivity. This study aimed to determine variations in plant growth, heritability, and genetic correlation of Manglid plants in a 2-year-old progeny test in Candiroto. A Randomized Completely Block Design with two components population and family used in this study. Families are nested within the population. There are 3 populations and 100 families; 15 of the 100 families were from Tasikmalaya, 10 were from Sumedang, and 75 were from Sukabumi. Plant height and stem diameter were measured. The analysis revealed a significant relationship between population, family, and family within the population and plant height and stem diameter development. Sumedang populations had the best height and diameter at 4.19 meters and 6.15 centimeters, with 27 differences in height growth and 24 variances in diameter growth at the family level. The estimated individual heritability for height was 0.21, while for stem diameter it was 0.17. The family heritability for height and stem diameter was 0.52 and 0.49, respectively. A 0.83 genetic correlation was found between height and diameter.

Genetic parameters and correlations in growth and wood density traits of Balfourodendron riedelianum based on provenance and progeny testing

Abstract Balfourodendron riedelianum is an important timber species of South America used in civil construction and carpentry. Knowing the genetic variation, heritability and correlation between traits is an essential prerequisite for guiding selection of the best genotypes in tree improvement. In this study, growth (diameter and height) and wood density (mean, pith, middle and bark position) traits were investigated in 30-year-old trees planted in a B. riedelianum provenance and progeny test established in two sites, Luiz Antônio (LA) and Pederneiras (PE), in São Paulo State (Brazil). ANOVA results showed significant differences between sites for all traits, among provenances and families for wood density traits in the LA site and among families for growth traits in PE. Provenance x site and family x site interactions were significant for almost traits, and genetic correlation between sites was low for all traits (0.17–0.20). Genetic variation (CV g) was higher (4.0–5.4 %) and mean family heritability (h m 2) was lower for growth (0.12–0.20) compared to wood density (CV g: 2.3–3.8%, h m 2: 0.31–0.59) traits. Genetic correlation was significantly positive and ranged from moderate to high between growth traits (0.47–0.68) and between wood density traits (0.42–0.83) and non-significant between growth and wood density (-0.22–0.30) traits. An analysis of different radial positions showed that heritability tended to increase from pith to the bark position. Our results show a lower environmental effect on wood density traits, allowing the possibility of selecting superior provenances and families with high wood quality in breeding programs in both sites.

Profiling of the genetic features of patients with breast, ovarian, colorectal and extracolonic cancers: Association to CHEK2 and PALB2 germline mutations

Background and aimsCancer predisposition goes beyond BRCA and DNA Mismatch Repair (MMR) genes since multi-gene panel testing has become the routine diagnostic tool for hereditary cancer suspicion (HCS) cases. CHEK2 and PALB2 are some of the foremost-mutated non-BRCA/MMR actionable genes in families with a significant familial aggregation. Therefore, the purpose of this work is to unravel which tumours other than breast, ovary or colorectal display the patients. Materials and methodsWe have analysed 528 probands that meet the inclusion criteria for Hereditary Breast and Ovarian Cancer and Lynch Syndrome established by our Hereditary Cancer Regional Program with a customized 35 genes-panel by using Ion Torrent™ Technology. ResultsWe have identified pathogenic variants (PVs) in 61 families (1.55%), of which more than half (31 probands) harboured PVs in CHEK2 and PALB2 genes. Ours results reveal that not only were PVs CHEK2 and PALB2 carriers more likely to have family history of cancer not limited to breast, ovarian or colorectal cancers, but also they are prone to other extracolonic cancers, noteworthy endometrial and gastric cancers. ConclusionsMultigene panel testing improves the chance of finding PVs in actionable genes in families with HCS. In addition, the coexistence of variants should be recorded to implement a polygenic risk algorithm that might explain the missing heritability in the aforementioned families.

Genetic stability observed in third-generation progeny trial of Acacia mangium: the importance of genotype by environment interaction assessment in advance generation breeding strategy

The breeding program for Acacia mangium has entered advanced-generation breeding cycles through adopting a recurrent selection system and a sub-lining breeding population. Genetic variation changes along the successive generations could affect its genetic stability on wide ranges of sites. The aim of this study is to observe genetic stability in third-generation progeny trials of A. mangium established at three different sites in Indonesia. Analysis was conducted, including single-site and multi-sites analyses for height, diameter, and stem forking that were grouped into two sets of analysis based on the genetic background of the trial: SET01 for the single sub-line and SET02 for the composite sub-lines. Index selection for multiple-traits was then used to identify the family changing ranks for multiple-traits and genetic gain prediction. The results showed that the recurrent selection system adopted in the breeding strategy for single-site analysis could maintain sufficient genetic variance of A. mangium in the third-generation progeny trial. Family heritability was moderate to high for almost all traits. However, a strong genetic-environment interaction (G × E) exists in multi-sites analysis for the single sub-line population (SET01), indicating a less sufficient genetic variation and a low Type B genetic correlation in anticipating a wider range of environment. On the contrary, compositing selected family from several sub-lines (SET02) could diminish the strength of G × E and increase Type B correlation. Selection and genetic gain prediction could be more effective in multi-sites analysis for SET02, but it was less effective for SET01. The results imply that adopting a recurrent selection system in advanced-generation breeding of A. mangium should consider structuring the breeding population. It could be practiced by compositing selected superior families from several sub-lines into one breeding population to maintain high genetic stability, while increasing genetic diversity and productivity.

Genetic Parameter Estimates for the Growth and Morphological Traits of Castanopsis hystrix Families and the Genotype × Environment Interaction Effects

Castanopsis hystrix, a timber resource from Southeast Asia, is characterized by rapid growth and high yield, but plantation quality and efficiency improvements are required. Twenty-year-old C. hystrix experimental forests in Yulin, Liuzhou, and Pingxiang in Guangxi Province, China, comprising 21 open-pollinated half-sib families, were used in this study. Genetic variations in the growth (tree height, diameter at breast height (DBH), and volume (V)) and morphological (height to live crown base (HCB), crown width (CW), and branch angle) traits were assessed, and the genetic parameters were estimated to clarify the genotype × environment interaction effects. The average values for the tree height, DBH, V, HCB, CW, and branch angle were 16.33 m, 17.25 cm, 0.21 m3, 6.68 m, 2.15 m, and 45.45°, respectively. The most important sources of variance for the tree height, DBH, V, and HCB were the block and family, whereas the location, family, and family × location had significant impacts on the tree height, DBH, V, and HCB (p < 0.01). The family heritability for each trait was 0.35, 0.38, 0.62, and 0.19, respectively. Excellent families with strong adaptability and genetic stability were identified using BLUP–GGE biplots for single and multiple traits. The results provide a theoretical basis for the efficient cultivation of C. hystrix in South China.

Investigation of familial tendency of endometriosis

Objective: To investigate the familial heritability of endometriosis and to compare the clinical characteristics of patients with or without a family history of endometriosis. Methods: From January 2020 to June 2022, 850 patients with endometriosis confirmed by laparotomy or laparoscopy in Peking University Third Hospital were included in this study. Clinical data were collected, family history was followed up, and the differences of clinical indicators between patients with and without family history of endometriosis were compared. Results: A total of 850 patients were enrolled, with an average age of (33.8±7.0) years old, 315 (37.1%, 315/850) patients in stage Ⅲ and 496 (58.4%, 496/850) patients in stage Ⅳ. There were 100 patients with family history of endometriosis, accounting for 11.8% (100/850). Most of the 113 relatives involved were mothers, daughters and sisters (76.1%, 86/113), 81.5% (22/27) of the second and third degree relatives were maternal relatives. The median ages of patients with and without family history of endometriosis were 30 and 33 years old respectively at the time of diagnosis. The unmarried rate of patients with family history was higher [42.0% (42/100) vs 26.3% (197/750)]. The percentage of dysmenorrhea patients with family history was higher [89.0% (89/100) vs 55.5% (416/750)]. The medians of dysmenorrhea score in patients with and without family history were 6 and 2, and the median durations of dysmenorrhea were 10 and 1 years. There were significant differences in age, marital status, percentage of dysmenorrhea, dysmenorrhea score and duration (all P<0.001). The median levels of serum cancer antigen (CA) 125 in patients with family history and patients without family history at the time of diagnosis were 57.5 and 46.9 kU/L respectively, with a statistically significant difference (P<0.05). However, there were no significant differences between the two groups in nationality, bady mass index, menarche age, menstrual cycle, menstrual period, menstrual volume, serum CA19-9 level, cyst location and size, stage, history of adverse pregnancy and childbirth, infertility, adenomyosis and deep infiltrating endometriosis (all P>0.05). By comparing the specific conditions of dysmenorrhea patients with and without family history of endometriosis, there were no significant differences between the two groups in terms of the age of onset of dysmenorrhea, duration of dysmenorrhea, primary and secondary dysmenorrhea, and progressive aggravation of dysmenorrhea (all P>0.05). The difference in the degree of dysmenorrhea in dysmenorrhea patients with family history of endometriosis was significant (P<0.001). Conclusions: The incidence of endometriosis has a familial tendency, and most of the involved relatives are the first degree relatives. Compared with patients without family history of endometriosis, endometriosis patients with family history are diagnosed at an earlier age, with higher percentage of dysmenorrhea, had more severe dysmenorrhea and higher serum CA125 level.

Early growth and genetic performance of Gelam (Melaleuca cajuputi subsp cumingiana) conservation plot: an endemic peatland species in South Sumatera

Gelam (Melaleuca cajuputi subsp cumingiana), is one of the endemic species that is under threat. A conservation plot was developed in the Banyuasin regency. It was designed as Gelam’s genetic conservation area and seed producing area in the near future. The plot was developed in Randomised Completely Block Design and consisted of 60 families, collected from Banyuasin and Bangka regency. It was stretched for 5 tree plots, 6 blocks, and 3x3 m of spacing. A preliminary study has been taken to record and evaluate Gelam’s growth over its genetic variation. It was shown that the survival of the species might vary (23% to 90%) with the population collected from Banyuasin performing a slightly better average. Further, the growth variation did not significantly differ between the two origins while the families affect performed significantly. The family heritability of the growth was moderate for height (h2f = 0.60) and low for diameter (h2f = 0.25) while its genetic correlation was strong (0.76). Through adequate technical support and suitable development strategy, this plot can be designed to provide the improved seed to boost degraded peatland rehabilitation in the region.

Special Report: Bipolar Disorder II—Frequently Neglected, Misdiagnosed

Special Report: Bipolar Disorder II—Frequently Neglected, Misdiagnosed

Comparison of genetic impact on growth and wood traits between seedlings and clones from the same plus trees of Pinus koraiensis

To evaluate the relationships among clones and open pollinated families from the same plus trees and to select elite breeding materials, growth, and wood characteristics of 33-year-old Pinus koraiensis clones and families were measured and analyzed. The results show that growth and wood characters varied significantly. The variation due to clonal effects was higher than that of family effects. The ratio of genetic to phenotypic coefficient of variation of clones in growth and wood traits was above 90%, and the repeatability of these characteristics was more than 0.8, whereas the ratio of genetic to phenotypic coefficient of variation of families was above 90%. The broad-sense heritability of all characteristics exceeded 0.4, and the narrow-sense family heritability of growth traits was less than 0.3. Growth characteristics were positively correlated with each other, but most wood properties were weakly correlated in both clones and families. Fiber length and width were positively correlated between clones and families. Using the membership function method, eleven clones and four families were selected as superior material for improved diameter growth and wood production, and two families from clonal and open-pollinated trees showed consistently better performance. Generally, selection of the best clones is an effective alternative to deployment of families as the repeatability estimates from clonal trees were higher than narrow-sense heritability estimates from open pollinated families. The results provide valuable insight for improving P. koraiensis breeding programs and subsequent genetic improvement.

Genetic parameters for resin production of Pinus merkusii progeny test collected from three landraces in Banyumas Barat Forest District, Indonesia

Abstract. Nugrahanto G, Na’iem M, Indrioko S, Faridah F, Widiyatno, Abdillah E. 2022. Genetic parameters for resin production of Pinus merkusii progeny test collected from three landraces in Banyumas Barat Forest District, Indonesia. Biodiversitas 23: 2010-2016. Pinus merkusii Jungh. et de Vriese is a native pine species in Indonesia that is used in the production of essential and economically valued products, such as wood and resin. The resin productivity can be increased significantly via breeding programs. The objective of this study is to analyze the genetic parameters of resin productivity based on the progeny performance in three landrace seeds sources, namely, Sumedang seedling seed orchards (SSOs), Jember SSO, and East Java seed source. The drilling method was used for tapping trees, and then resin production was measured individually. Additional data on height, diameter, and branch-free height were also collected. Based on family variance component analysis data of resin production, it was noted that Sumedang SSO, Jember SSO, and East Java seed sources have relatively high genetic variations of 4.48%, 15.77%, and 3.80%, respectively. These values were then followed by a moderate family heritability value for all of them (0.451-0.551). A high value of individual heritability estimates was obtained for Jember SSO (0.658), and moderate values were found for Sumedang SSO (0.182) and East Java seed sources (0.158), respectively. The estimated genetic gains were calculated for resin production using selection intensity levels at 10%, 25%, and 50%. The result indicated that the Jember SSO landrace obtained the highest genetic gains at 17.55%, 12.73%, and 7.99%, for the above-mentioned intensity levels, respectively. In contrast, the lowest one was found in the Sumedang SSO landrace.

EVALUASI PERTUMBUHAN TANAMAN UJI KETURUNAN TEMBESU (Fagraea fragrans ROXB) UMUR 3 TAHUN DI KHDTK KEMAMPO KABUPATEN BANYUASIN

Tembesu (Fagraea fragrans Roxb) is a local superior plant species in South Sumatra. The lots of use has resulted in a decrease in the potential of these plants in natural forests. The length for recycling of tembesu plants is problem in the cultivation of it. One of the ways to overcome this problem is by plant breeding. This study aimed to determine plant growth and genetic variation of 3 years old tembesu (Fagraea Fragrans ROXB) in KHDTK Kemampo, Kabupaten Banyuasin, South Sumatra Province. This study uses Incomplete Block Design with rows and columns, 55 families, 20 replications. The results showed that Provenan had no significant effect on all observed variables, while plant family had a very significant effect on plant height and stem diameter and significantly affected for tree volume. The highest average plant is found in family 20 is 4.79 m, the largest average diameter is found in family 35 is 7.02 cm, the largest average volume is found in family 35 is 0.0177 m3. For genetic parameters, the value of individual heritability was at a high level of 0.37 for plant height, and was at a moderate level for trunk diameter and tree volume, while the value of family heritability was at a high level of 0.65 for plant height variables and was at low levels for trunk diameter and tree volume. the genetic correlation between height and stem diameter has a high value, which is 0.67. Estimated genetic gain at the 5% selection level shows a fairly high value, namely 7.84% for plant height, 4.51% for stem diameter, and 36.62 for tree volume. Key words: Tembesu plant (Fagraea fragrans ROXB) 3 years old, progeny test, growth, genetic variation, evaluation

Estimating heritability using family-pooled phenotypic and genotypic data: a simulation study applied to aquaculture

Estimating heritability based on individual phenotypic and genotypic measurements can be expensive and labour-intensive in commercial aquaculture breeding. Here, the feasibility of estimating heritability using within-family means of phenotypes and allelic frequencies was investigated. Different numbers of full-sib families and family sizes across ten generations with phenotypic and genotypic information on 10 K SNPs were analysed in ten replicates. Three scenarios, representing differing numbers of pools per family (one, two and five) were considered. The results showed that using one pool per family did not reliably estimate the heritability of family means. Using simulation parameters appropriate for aquaculture, at least 200 families of 60 progeny per family divided equally in two pools per family was required to estimate the heritability of family means effectively. Although application of five pools generated more within- and between- family relationships, it reduced the number of individuals per pool and increased within-family residual variation, hence, decreased the heritability of family means. Moreover, increasing the size of pools resulted in increasing the heritability of family means towards one. In addition, heritability of family mean estimates were higher than family heritabilities obtained from Falconer’s formula due to lower intraclass correlation estimate compared to the coefficient of relationship.

Variation and Genetic Control of the Heartwood, Sapwood, Bark, Wood Color Parameter, and Physical and Mechanical Properties of Dipteryx panamensis in Costa Rica

The Dipteryx genus has a natural distribution throughout several tropical countries in Latin America. This taxon has several tree species, all recognized for their high-density wood. The objective of this research was to study the variation and genetic control of several wood properties, including bark, sapwood, heartwood, green density (GD), specific gravity (SG), moisture content in green condition (MC-G), and mechanical properties, in a Dipteryx panamensis provenance/progeny test at 8 years old. The results showed that bark varied little among families and provenances, but heartwood (diameter and percentage) showed high genetic variation. SG and MC-G showed significant variation between provenances and families, while GD showed little variation. Among the mechanical properties evaluated, the greatest genetic variation was observed in the MOR in bending and shear stress. Families from the Coope San Juan provenance registered the highest values in all wood properties investigated, and families from Puerto Viejo obtained the lowest. Family heritability and the coefficient of genetic variation exhibited high values in heartwood/sapwood and the MOR in bending (h2 &gt; 0.9 and CV &gt; 20%) and lower values in SG, MC-G, compression stress, and shear stress. D. panamensis wood properties have a high potential to be improved through breeding programs.

PERTUMBUHAN DAN PARAMETER GENETIK TANAMAN UJI KETURUNAN MINDI (Melia azedarach Linn.) DI HUTAN PENELITIAN PARUNGPANJANG, BOGOR

Mindi (Melia azedarach Linn., family Meliaceae) is a multipurpose forest tree species such as for furniture, vinier and plywood, otherwise the leaves for pesticide and medicine material. Mindi mostly cultivated in a community forest, especially in West Java. This study was aimed to assess the growth performance and genetic parameter of the progeny test of mindi at Parungpanjang Forest Research Station, Bogor, West Java. The progeny test was established by using a randomized complete block design, consisting of 6 blocks and 73 families and each family consisting of 4 trees row-plot. The survival at 7 years old was 57.48%, height was 7.15 m and diameter is 8.59 cm, in average. The height and diameter growths among families showed a significantly different. The best family growth in height and diameter were Sumedang-31 and Bogor-18 families, respectively.The individual and family heritabilities for both stem diameter and tree heght characters were stil relatively low, with the higher family heritability value than individual heritability. The genetic correlation between total height and stem diameter of 0.57 indicates a strong correlation between the traits.

Mahogany (Swietenia macrophylla King.) as urban tree: tree growth and wood quality variation in a progeny test

Mahogany (Swietenia macrophylla) is a tree species widely planted not only for timber production but also as a shade tree in urban areas both on the side of the highway (green belt) and other green open areas. The objective of this study was to analyze the genetic variation of growth and wood quality of a mahogany progeny test at the Parung Panjang, Bogor, which will be converted into a seedling seed orchard for high quality seed production. The progeny test was established using a randomized complete block design involving 96 families originating from seven populations (land races) in Java Island, i.e., Cianjur, Sumedang, Tasikmalaya, Magelang, Gundih, Madiun, and Jember. The results showed that the family had a significant effect on all the growth and wood quality parameters. Individual and family heritability for all growth and wood quality traits were categorized into the high, i.e., 0.33 - 0.96 and 0.35 - 0.56, respectively. The selection simulation showed that the selection percentage of 44.68% (45 best families) gave the optimum genetic gain based on growth and wood quality traits.

Growth diversity, heritability, and genetic correlation of 4-years-old of Alstonia angustiloba progeny test in Wonogiri, Central Java

Alstonia angustiloba is a local tree species that have potential for community forest plantation; therefore, it is important to provide improved seeds. This study aimed to determine the diversity of growth, estimate the value of heritability, and the genetic correlation of the 4-years-old A. angustiloba progeny test. Randomized Completely Block Design with two factors (population and family) were used in this study. In this study, families are nested in the population. The population factors consisted of 4 levels, and family factors consisted of 43 families. The analysis of variance showed that height and stem diameter growth were significantly different between populations and families at four years old. The best height and stem diameter growth at the population level was obtained from the Pendopo population, 4.45 m and 7.71 cm, respectively. At the family level, the best height growth was obtained from 9 families (4.46-5.06 m), and the best stem diameter growth was obtained from 11 families (7.48-8.72 cm). The estimated individual heritability value for height was 0.41, and stem diameter was 0.23. Estimated family heritability values were 0.66 for height and 0.50 for stem diameter. The genetic correlation between height and stem diameter was 0.97.

Genetic Analysis of Growth Characteristics of Acer catalpifolium Half-sib Family at Seedling Stage

In order to provide reference for the protection and development of Acer catalpifolium, the growth performance of Acer catalpifolium at seedling stage was studied, and the families with good growth traits at the seedling stage were screened. Fifteen half-sib families of Acer catalpifolium were used as the research object, the growth of seedling height and ground diameter traits were analyzed and compared. The results showed that there were significant differences in seedling height and ground diameter of half-sib families of Acer catalpifolium. The family heritability of seedling height and ground diameter was greater than 0.9. There was a significant positive correlation between seedling height and ground diameter. The genetic coefficients of seedling height and ground diameter reached 30.59% and 29.06%, respectively, with great potential for genetic improvement. Two excellent half-sib families were screened.