Abstract This article examines the effectiveness of Mode Deactivation Family Therapy, (MDT) in an outpatient setting as compared to Treatment as Usual, (TAU). MDT is an evidenced based psychotherapy and has been shown to be effective treating adolescents with a variety of problems involving emotional disorder, physical and sexual aggression, as well as behaviors associated with anxiety and trauma. In this study, MDT was shown to be superior to TAU in an outpatient setting with improving family relationships and reducing family disharmony of the previous described adolescents. Keywords: Mode Deactivation Therapy, (MDT), Treatment as Usual, (TAU), MDT Family Therapy. Introduction Mode Deactivation therapy (MDT) has been shown to be an effective treatment for a variety of adolescent disorders, Apsche, Bass & Siv (2006). Disorders that MDT has been shown to be effective with include emotional, Apsche & Ward-Bailey (2004) behavioral, Apsche, Bass, Murphy, (2006), physical aggression, Apsche, Bass & Houston, (2007), sexual aggression, Apsche, Bass, Jennings, Murphy, Hunter & Siv (2005), and many harmful symptoms of anxiety and traumatic stress, Apsche & Bass (2006). MDT Family Therapy has been effective in reducing family disharmony in case studies, (Apsche & Ward (2004) and has been shown to be efficacious as compared to TAU, in treating families with a variety of problem behaviors, Apsche & Bass, (2006) and in reducing and maintaining treatment effects thru two (2) years of tracking recidivism rates (Apsche, Bass & Houston, 2007). Apsche, Bass & Siv, (2006) completed a Family MDT clinical study of 14 adolescents with problems with sexual and physical aggression and oppositional behaviors, such as, not following parent's direction, oppositional and verbal aggression. The results suggest that MDT performed Treatment As Usual (TAU); at the eighteenth month of observation, the MDT group has zero, (0) sexual recidivism, while the TAU group had 10 reported incidents or problems with sexual behavior. The MDT group reported (3) three incidents of physical aggression while the TAU group reported (12) twelve incidents. The results were promising for MDT as a Family Therapy, but the small size of the group rendered the effects of the study as having some limitation, and in need of further study with a larger group; however, results are suggestive of a promising methodology. Apsche, Bass & Houston (2007), completed a study of Family MDT with an additional (8) eight families in the community, as compared to a separate TAU group. The Apsche, et. al., 2007, study examined physically aggressive youths with personality and conduct problems. The study had a total of families of (15) fifteen, (8) eight in the MDT group and (7) seven in the TAU group. MDT out-performed TAU at the twenty week interval of treatment. The most compelling point of data was that the MDT group had (0) zero referrals for out of home placements, while the TAU group has referrals fore of home placements. The results are promising, yet the small number of participants limits the claims of the effects of Family MDT. A major problem of treatment research is that large adequate sample sizes are not always available. Referred clients and families are sent for treatment. The sent client or families, by nature, usually enter treatment with a level of resistance. The resistance is based on the issue that someone else determined that there are problems within the family. The sources of these referrals are typically a court or department of Children and Youth. The clinician researcher has to find a strategy to motivate the family to work hard to address their issues and problems. MDT, both in individual and family work, offers the therapist and client(s) the ability to structure, measure and track progress in treatment in the Family Manual, Apsche & Apsche (2007). …