Stroke survivors' and their family caregivers' (stroke dyads) coping during the inpatient period can affect their short- and long-term health and well-being. This study aimed to investigate whether survivors' and caregivers' psychosocial factors (i.e., depression, anxiety, family functioning, and mutuality) were associated with their own and their counterparts' perceptions of family coping among inpatient stroke dyads. A cross-sectional design was adopted for this study which included 162 stroke dyads. Family coping, depression, anxiety, family functioning, and mutuality were measured using the Family Crisis-Oriented Personal Evaluation Scale, Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, General Functioning subscale of Family Assessment Device, and Mutuality Scale, respectively. The actor-partner interdependence model estimated by path analysis was performed for the dyadic data. The results revealed that survivors' own (depression: β = -0.337, p < .001) and their counterparts' (caregivers' anxiety: β = -0.220, p = .021) psychological symptoms were negatively associated with survivors' perceptions of family coping, whereas none of them were associated with caregivers' perceptions of family coping. Moreover, higher family functioning reported by the survivors (β = -0.375, p < .001) and family caregivers (β = -0.195, p = .029) were associated with better family coping perceived by both counterparts, respectively. This study highlights that stroke dyads' psychosocial factors play a vital role in their perceptions of family coping. Future studies can be conducted to develop coping-focused interventions from the dyadic or family-oriented approach regarding psychosocial states as potential targets for inpatient stroke dyads. (PsycInfo Database Record (c) 2024 APA, all rights reserved).